Patents by Inventor Wayne Xu

Wayne Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200261578
    Abstract: The present invention comprises human monoclonal antibodies that bind to GITR (also known as glucocorticoid-induced tumor necrosis factor receptor) Binding of the invented antibody to GITR inhibits binding of its ligand, GITR-L, and can be used to treat cancer.
    Type: Application
    Filed: November 4, 2019
    Publication date: August 20, 2020
    Inventors: Wayne A. Marasco, Chen Xu, De-Kuan Chang
  • Publication number: 20200165357
    Abstract: The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
    Type: Application
    Filed: October 21, 2019
    Publication date: May 28, 2020
    Inventors: Wayne A. Marasco, Agnes Lo, Chen Xu, Quan Zhu
  • Patent number: 10545308
    Abstract: A flat drop cable has notches or other structures for enhancing the stripability of the jacket from the a core of the flat drop cable. The notches can have an angled configuration with surfaces that converge as the notch extends into the jacket. Inner edges of the notches can be positioned along a tear path that intersects the core of the flat drop cable. For example, the notches can be offset from a minor axis of the flat drop cable a sufficient distance such that the notches are positioned outside a central boundary region that extends tangent to sides of the core and parallel to the minor axis of the flat drop cable.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: January 28, 2020
    Assignees: CommScope Technologies LLC, CommScope Technologies Australia Pty Ltd., CommScope Telecommunications (Shanghai) Co., Ltd.
    Inventors: Aly Fahd, Wayne M. Kachmar, Steven James Dick, Paul David Hubbard, Wei Fu, Dong Xu
  • Patent number: 10472084
    Abstract: A system for driving an environmental control system (ECS) of a vehicle with ground-based electrical power may include a turbine engine on board the vehicle, coupled to the ECS to pneumatically drive the ECS, and an electric machine, on board the aircraft, mechanically coupled to the turbine engine, to drive the turbine engine. A control system such that the electric machine provides motoring assistance to the turbine engine, and that the motoring assistance is limited to match the available current from the ground-based electrical power.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: November 12, 2019
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Ming Xu, Cristian Anghel, Eric Blumer, Wayne Pearson
  • Patent number: 10463732
    Abstract: The present invention comprises human monoclonal antibodies that bind to GITR (also known as glucocorticoid-induced tumor necrosis factor receptor). Binding of the invented antibody to GITR inhibits binding of its ligand, GITR-L, and can be used to treat cancer.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: November 5, 2019
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Wayne A. Marasco, Chen Xu, De-Kuan Chang
  • Patent number: 10450383
    Abstract: The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: October 22, 2019
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Wayne A. Marasco, Agnes Lo, Chen Xu, Quan Zhu
  • Publication number: 20190187398
    Abstract: A flat drop cable has notches or other structures for enhancing the stripability of the jacket from the a core of the flat drop cable. The notches can have an angled configuration with surfaces that converge as the notch extends into the jacket. Inner edges of the notches can be positioned along a tear path that intersects the core of the flat drop cable. For example, the notches can be offset from a minor axis of the flat drop cable a sufficient distance such that the notches are positioned outside a central boundary region that extends tangent to sides of the core and parallel to the minor axis of the flat drop cable.
    Type: Application
    Filed: December 10, 2018
    Publication date: June 20, 2019
    Applicants: COMMSCOPE TECHNOLOGIES LLC, COMMSCOPE TELECOMMUNICATIONS (SHANGHAI) CO. LTD., COMMSCOPE CONNECTIVITY AUSTRALIA PTY LTD., ADC COMMUNICATIONS (AUSTRALIA) PTY LIMITED
    Inventors: Aly FAHD, Wayne M. KACHMAR, Steven James DICK, Paul David HUBBARD, Wei FU, Dong XU
  • Patent number: 6630543
    Abstract: A method of making a biodegradable polymer composition including the steps of providing a first component being either one of a thermoplastic poly(hydroxy ester ether) or a synthetic, hydroxy-functional polymer and providing a second component being a natural polymer. The method includes the steps of mixing the first component and second component together to form a mixture, compounding the mixture, and pelletizing the compounded mixture to form pellets of a biodegradable polymer composition.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: October 7, 2003
    Assignees: Biotechnology Research and Development Corporation, The United States of America as represented by the Secretary of Agriculture
    Inventors: William M. Doane, Wayne Xu, Michael N. Mang, Jerry E. White, Julious L. Willett
  • Patent number: 6054510
    Abstract: Compositions of the invention include a hydroxy-functional polyester and a natural polymer. Articles can be made from such a composition so as to have sufficiently strong tensile strengths as to form disposable utensils or to have sufficient stretchability so as to form thin wrap films. However, the compositions are more environmentally friendly than commodity plastics such as polyethylene or polystyrene. Granular starches derived from a grain, a root, a legume, or mixtures thereof, are particularly preferred as the natural polymers for inclusion in the compositions.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: April 25, 2000
    Assignees: The United States of America as represented by the Secretary of the Agriculture, Biotechnology Research and Development Corporation
    Inventors: Julious L. Willett, William M. Doane, Wayne Xu, Michael N. Mang, Jerry E. White
  • Patent number: 6042902
    Abstract: Multilayer films that include a thermotropic liquid crystalline polymer film layer and a poly(ethylene terephthalate) or polycarbonate film layer are bound together using a hot melt adhesive, which may be either (1) a blend of poly(.alpha.-olefins) that includes isotactic polypropylene, a polymer of a second lower poly(.alpha.-olefin), and a small amount of a higher poly(.alpha.-olefin); or (2) a polyamide-based hot melt adhesive.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: March 28, 2000
    Assignee: Hoechst Celanese Corporation
    Inventors: James E. Kuder, Dominick Cangiano, Vincent J. Provino, Wayne Xu
  • Patent number: 6025417
    Abstract: Compositions of the invention include particular hydroxy-functional polyesters and a natural polymer. Among articles that can be made from such compositions are those with sufficiently strong tensile strengths as to form disposable utensils. However, the compositions are more environmentally friendly than commodity plastics such as polyethylene or polystyrene. Starches are particularly preferred as the natural polymers for inclusion in the compositions.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: February 15, 2000
    Assignees: Biotechnology Research & Development Corp., The United States of America as represented by the Secretary of the Agriculture
    Inventors: Julious L. Willett, William M. Doane, Wayne Xu, Michael N. Mang, Jerry E. White
  • Patent number: 6015524
    Abstract: Multilayer films that include a thermotropic liquid crystalline polymer film layer and a polyethylene film layer are bound together using one of the following hot melt adhesives: ethylene-glycidyl methacrylate copolymer, ethylene-methyl acrylate-glycidyl methacrylate terpolymer, ethylene vinyl acetate copolymer, a polyolefin blend, ethylene-acrylic acid copolymer, and mixtures thereof.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: January 18, 2000
    Assignee: Hoechst Celanese Corporation
    Inventors: James E. Kuder, Dominick Cangiano, Vincent J. Provino, Wayne Xu
  • Patent number: 6013373
    Abstract: Multilayer films that include a thermotropic liquid crystalline polymer film layer and a polypropyene film layer are bound together using hot melt adhesives which may be either (1) a blend of poly(.alpha.-olefins), comprised of isotactic polypropylene, a polymer of a second lower poly(.alpha.-olefin), and a small amount of a higher poly(.alpha.-olefin), or (2) a blend of poly(propylene-graft-maleic anhydride) and a dimer acid based polyamide. These hot melt adhesives also act as compatiblizers for blends of polypropylene and thermotropic liquid crystalline polymers.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: January 11, 2000
    Assignee: Hoechst Celanese Corporation
    Inventors: James E. Kuder, Dominick Cangiano, Vincent J. Provino, Wayne Xu
  • Patent number: 5854345
    Abstract: Expanded articles have a compressible and resilient body including two biodegradable components. One component preferably is starch or a modified starch. Another component is a water insoluble, synthetic polymer, preferably a hydroxy-functional polyester. The article may be thermoformed, and has exterior surfaces with substantial resistance to moisture.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: December 29, 1998
    Assignees: The United States of America as represented by the Secretary of Agriculture, Biotechnology Research & Development Corporation
    Inventors: Wayne Xu, William M. Doane
  • Patent number: 5852078
    Abstract: Compositions of the invention include a hydroxy-functional polyester and a natural polymer. Articles can be made from such a composition so as to have sufficiently strong tensile strengths as to form disposable utensils or to have sufficient stretchability so as to form thin wrap films. However, the compositions are more environmentally friendly than commodity plastics such as polyethylene or polystyrene. Granular starches derived from a grain, a root, a legume, or mixtures thereof, are particularly preferred as the natural polymers for inclusion in the compositions.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: December 22, 1998
    Assignees: The United States of America as represented by the Secretary of Agriculture, Biotechnology Research and Development Corporation
    Inventors: Julious L. Willett, William M. Doane, Wayne Xu, Michael N. Mang, Jerry E. White
  • Patent number: 5821286
    Abstract: Biodegradable films include two biodegradable components. One component preferably is starch while the other component is a water insoluble, synthetic polymer, preferably a hydroxy-functional polyester.
    Type: Grant
    Filed: May 24, 1996
    Date of Patent: October 13, 1998
    Assignees: The United States of America as represented by the Secretary of the Agriculture, Biotechnology Research & Development Corporation
    Inventors: Wayne Xu, William M. Doane, John W. Lawton, Jr.
  • Patent number: 5665786
    Abstract: Expanded articles have a compressible and resilient body including two biodegradable components. One component preferably is starch or a modified starch. Another component is a water insoluble, synthetic polymer, preferably a hydroxy-functional polyester. The article may be thermoformed, and has exterior surfaces with substantial resistance to moisture.
    Type: Grant
    Filed: May 24, 1996
    Date of Patent: September 9, 1997
    Assignee: Bradley University
    Inventors: Wayne Xu, William M. Doane