Abstract: Provided is a vaccine composition for preventing respiratory syncytial virus (RSV) infection, which is in the form of a liposome formulation including a RSV antigen, monophosphoryl lipid A (MLA), and/or a cobalt-porphyrin-phospholipid (CoPoP) conjugate. The vaccine composition exhibits excellent vaccine efficacy from a RSV antigen with enhanced immunogenicity and a combination of immune adjuvants for enhancing immune activity and antigen presentation.

Abstract: Provided are a vaccine composition for Varicella Zoster virus (VZV) including a glycoprotein E (gE) antigen of VZV and monophosphoryl lipid A (MLA), and a method of using the same. The vaccine composition according to an aspect of the invention may significantly improve a production yield by including the gE antigen having an optimized signal peptide sequence, may enhance immunogenicity by including MLA, and may further enhance the immunogenicity enhanced by MLA by further adding saponin such as QS-21, and may be prepared in a form of CoPoP liposomes so that vaccine antigens may be presented on the surface of the liposomes for better absorption by antigen-presenting cells, and vaccine efficacy may be maximized by inclusion of the vaccine antigens and immune adjuvants in a formulation. Therefore, the vaccine composition may be useful as an alternative to current vaccines in the art for prevention or treatment of VZV infection.

Abstract: The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules comprising epitopes from microorganisms with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.

Abstract: A hub device and a power supply method thereof are provided. The hub device includes a power input port, first and second power output ports, a power management circuit and a controller. When first and second electronic devices are respectively connected to the first and second power output ports, the controller determines an input electric power from at least one default supply power of the power adapter based on first operating power information of the first electronic device and second operating power information of the second electronic device, so as to control the power adapter to provide the input electric power to the power input port. The power management circuit receives the input electric power to generate first and second operating power, so as to output the first operating power to the first power output port and output the second operating power to the second power output port.

Abstract: A hub device and a power supply method thereof are provided. The hub device includes a power input port, first and second power output ports, a power management circuit and a controller. When first and second electronic devices are respectively connected to the first and second power output ports, the controller determines an input electric power from at least one default supply power of the power adapter based on first operating power information of the first electronic device and second operating power information of the second electronic device, so as to control the power adapter to provide the input electric power to the power input port. The power management circuit receives the input electric power to generate first and second operating power, so as to output the first operating power to the first power output port and output the second operating power to the second power output port.

Abstract: The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules comprising epitopes from microorganisms with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.

Abstract: The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.

Abstract: The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.

Abstract: A power control device for an electronic device includes a power switching unit for switching to output a dc power source to a load of the electronic device according to a power switching signal, a switching detection unit for responding a power switching status to generate a switching detection signal, a status latch module for generating the power switching signal according to the switching detection signal, a first status signal and a second status signal, and a logic unit for generating the first status signal and the second status signal for the status latch module according to the power switching signal, such that the status latch module latches the first status signal and the second status signal.

Abstract: A power control device for an electronic device includes a power switching unit for switching to output a dc power source to a load of the electronic device according to a power switching signal, a switching detection unit for responding a power switching status to generate a switching detection signal, a status latch module for generating the power switching signal according to the switching detection signal, a first status signal and a second status signal, and a logic unit for generating the first status signal and the second status signal for the status latch module according to the power switching signal, such that the status latch module latches the first status signal and the second status signal.