Patents by Inventor Wei-Ching Liang

Wei-Ching Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Binding polypeptides with diversified and consensus VH/VL hypervariable sequences
    Patent number: 8679490
    Abstract: The invention provides variant hypervariable regions comprising selected amino acid sequence diversity. Libraries comprising a plurality of these polypeptides are also provided. In addition, methods of and compositions for generating and using these polypeptides and libraries are provided.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: March 25, 2014
    Assignee: Genentech, Inc.
    Inventors: Mark S. Dennis, Wei-Ching Liang, Yan Wu
  • Inhibition of tumor metastasis by anti neuropilin 2 antibodies
    Patent number: 8648173
    Abstract: The application provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: February 11, 2014
    Assignee: Genentech, Inc.
    Inventors: Yan Wu, Wei-Ching Liang, Ryan Jefferson Watts, Anil Durgadas Bagri
  • ANTI-LGR5 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20130336885
    Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: March 29, 2013
    Publication date: December 19, 2013
    Applicant: GENENTECH INC.
    Inventors: Jo-Anne Hongo, Weiguang Mao, Paul Polakis, Andrew Polson, Rajesh Vij, Yan Wu, Wei-Ching Liang
  • ANTI-VEGF ANTIBODIES
    Publication number: 20130315918
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: June 27, 2013
    Publication date: November 28, 2013
    Applicant: Genentech, Inc.
    Inventors: GERMAINE FUH, HANS-PETER GERBER, WEI-CHING LIANG, FREDERIC FELLOUSE, SACHDEV S. SIDHU, CHRISTIAN WIESMANN
  • ANTI-VEGF ANTIBODIES
    Publication number: 20130266581
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: June 25, 2013
    Publication date: October 10, 2013
    Inventors: Germaine FUH, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Antibodies and immunoconjugates and uses therefor
    Patent number: 8524865
    Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: September 3, 2013
    Assignee: Genentech, Inc.
    Inventors: Allen J. Ebens, Jr., Alane M. Gray, Wei-Ching Liang, Yan Wu, Shang-Fan Yu
  • Anti-VEGF antibodies
    Patent number: 8512699
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: August 20, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Anti-VEGF antibodies
    Patent number: 8492527
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: July 23, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR
    Publication number: 20130171170
    Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: June 12, 2012
    Publication date: July 4, 2013
    Applicant: GENENTECH, INC.
    Inventors: ALLEN J. EBENS, JR., ALANE M. GRAY, WEI-CHING LIANG, YAN WU, SHANG-FAN YU
  • ANTI-TAT226 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20130156693
    Abstract: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: June 20, 2013
    Inventors: Wei-Ching Liang, Chie Sakanaka, Yan Wu
  • NOVEL ANTI- ALPHA5BETA1 ANTIBODIES AND USES THEREOF
    Publication number: 20130095096
    Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
    Type: Application
    Filed: December 22, 2011
    Publication date: April 18, 2013
    Applicant: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • Anti-CD22 antibodies and immunoconjugates and methods of use
    Patent number: 8394607
    Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: March 12, 2013
    Assignee: Genentech, Inc.
    Inventors: Allen J. Ebens, Jr., Alane M. Gray, Wei-Ching Liang, Yan Wu, Shang-Fan Yu
  • Anti-CD22 Antibodies And Immunoconjugates and Methods of Use
    Publication number: 20120329094
    Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: July 26, 2012
    Publication date: December 27, 2012
    Applicant: Genentech, Inc.
    Inventors: Allen J. Ebens, JR., Alane M. Gray, Wei-Ching Liang, Yan Wu, Shang-Fan Yu
  • ANTI-VEGF ANTIBODIES
    Publication number: 20120322982
    Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 20, 2012
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
  • Antibodies and immunoconjugates and uses therefor
    Patent number: 8226945
    Abstract: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: July 24, 2012
    Assignee: Genentech, Inc.
    Inventors: Allen J. Ebens, Jr., Alane M. Gray, Wei-Ching Liang, Yan Wu, Shang-Fan Yu
  • NOVEL ANTIBODIES
    Publication number: 20120156129
    Abstract: The present invention relates to the use of VEGF antagonists and a novel anti-?5?1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-?5?1 antibodies and methods of making and using them.
    Type: Application
    Filed: May 20, 2011
    Publication date: June 21, 2012
    Applicant: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • NOVEL ANTIBODIES
    Publication number: 20120148572
    Abstract: The present invention relates to the use of VEGF antagonists and a novel anti-?5?1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-?5?1 antibodies and methods of making and using them.
    Type: Application
    Filed: May 20, 2011
    Publication date: June 14, 2012
    Applicant: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
  • Anti-TAT226 antibodies and immunoconjugates
    Patent number: 8183347
    Abstract: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: May 22, 2012
    Assignee: Genentech, Inc.
    Inventors: Wei-Ching Liang, Chie Sakanaka, Yan Wu
  • ANTI-TAT226 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20120100159
    Abstract: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: March 16, 2007
    Publication date: April 26, 2012
    Inventors: Wei-Ching Liang, Chie Sakanaka, Yan Wu
  • Anti- ?5 ?1 antibodies and uses thereof
    Patent number: 8124740
    Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: February 28, 2012
    Assignee: Genentech, Inc.
    Inventors: Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye