Patents by Inventor Wei-Chuan Sun

Wei-Chuan Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide-based multimeric targeted contrast agents
    Patent number: 6991775
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: January 31, 2006
    Assignee: Epix Medical, Inc.
    Inventors: Steffi K. Koerner, Andrew Kolodziej, Thomas J. McMurry, Shrikumar Nair, Alexander L. Nivorozhkin, Wei-Chuan Sun, Xifang Wang
  • Peptide-based multimeric targeted contrast agents
    Publication number: 20030216320
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: July 30, 2002
    Publication date: November 20, 2003
    Inventors: Steffi K. Koerner, Andrew Kolodziej, Thomas J. McMurry, Shrikumar Nair, Alexander L. Nivorozhkin, Wei-Chuan Sun, Xifang Wang
  • Fluorinated xanthene derivatives
    Patent number: 6162931
    Abstract: The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess greater photostability and have lower sensitivity to pH changes in the physiological range of 6-8 than do non-fluorinated dyes, exhibit less quenching when conjugated to a substance, and possess additional advantages. The dyes of the invention are useful as detectable tracers and for preparing conjugates of organic and inorganic substances.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: December 19, 2000
    Assignee: Molecular Probes, Inc.
    Inventors: Kyle R. Gee, Martin Poot, Dieter H. Klaubert, Wei-Chuan Sun, Richard P. Haugland, Fei Mao
  • Derivatives of 6,8-difluoro-7-hydroxycoumarin
    Patent number: 5830912
    Abstract: The present invention comprises 6,8-difluoro-7-hydroxycoumarins and derivatives of 6,8-difluoro-7-hydroxycoumarins, including reactive dyes, dye-conjugates and enzyme substrates. These fluorine-substituted fluorescent dyes typically possess greater photostability and lower pH sensitivity in the physiological pH range than their nonfluorinated analogs, exhibit less fluorescence quenching when conjugated to a substance, possess absorption and emission spectra that closely match those of their nonfluorinated analogs, and also exhibit higher quantum yields than their nonfluorinated analogs.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: November 3, 1998
    Assignee: Molecular Probes, Inc.
    Inventors: Kyle R. Gee, Richard P. Haugland, Wei-Chuan Sun