Abstract: Disclosed are an antibody that can bind to human MASP-2, a preparation method therefor and an application thereof. The anti-human MASP-2 antibody of the present invention can specifically bind to human MASP-2, has good biological activity of inhibiting the cleavage of C4 and the generation of C3b, and can be applied in the treatment of MASP-2 related diseases, such as IgA nephropathy.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: A method and device for obtaining microscopic occurrence characteristics of oil stored in a shale, where the microscopic occurrence characteristics include the adsorbed oil film thicknesses in the shale and the oil distribution in the shale. The method includes four steps. The first step is an experiment step in which a N-Hexane vapor adsorption experiment is performed on a sample made from a shale. The second step is a first obtaining step for calculating and obtaining the adsorbed oil film thicknesses in the shale. The third step is a first calculating step and the fourth step is a second obtaining step. They aim to obtain the oil distribution in the shale.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: An oil-water separation apparatus has a housing that contains at least one longitudinal plate member arranged in a longitudinal direction of the housing (10) and inclined relative to a horizontal direction. The longitudinal plate member forms at least one fluid channel in an inner chamber of the housing. A first guiding hole is provided on the longitudinal plate member or between the longitudinal plate member and an inner wall of the housing, and is in communication with the fluid channel. A second guiding hole is provided on the longitudinal plate member or between the longitudinal plate member and the inner wall of the housing, and is in communication with the fluid channel and is placed lower than the first guiding hole is positioned. A collection pipe is arranged at a longitudinal downstream end of the housing, and is in communication with the inner chamber of the housing.

Abstract: A method and device for obtaining microscopic occurrence characteristics of oil stored in a shale, where the microscopic occurrence characteristics include the adsorbed oil film thicknesses in the shale and the oil distribution in the shale. The method includes four steps. The first step is an experiment step in which a N-Hexane vapor adsorption experiment is performed on a sample made from a shale. The second step is a first obtaining step for calculating and obtaining the adsorbed oil film thicknesses in the shale. The third step is a first calculating step and the fourth step is a second obtaining step. They aim to obtain the oil distribution in the shale.

Abstract: An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.

Abstract: An anti-human IL-17A monoclonal antibody, the preparation method, and the use thereof are provided. The anti-human IL-17A monoclonal antibody can specifically bind to human IL-17A and has a good effect for inhibiting the secretion of inflammatory cytokines, such as IL-6 and the like by means of various cell lines induced by IL-17A, and can be used for preparing drugs for treating diseases involving immune-medicated inflammatory responses.

Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Disclosed herewith a separation device for performing phase separation on a three-phase liquid. The device includes: a housing; at least one pair of longitudinal baffle plates; a flow channel formed between every pair of longitudinal baffle plates; and collection chambers formed between adjacent pairs of longitudinal baffle plates. Each collection chamber is provided with a transverse baffle plate to separate the collection chamber into a first phase and a second phase collection cells. Each flow channel is provided with multiple lateral baffle plates to separate the flow channel into multiple sub-channels. In the areas of each longitudinal baffle plate where the first phase and second phase collection cells are located respectively, said longitudinal baffle plate is provided with a first and a second phase guiding holes in communication with the first phase and the second collection cells respectively.

Abstract: An anti-human IL-17A monoclonal antibody, the preparation method, and the use thereof are provided. The anti-human IL-17A monoclonal antibody can specifically bind to human IL-17A and has a good effect for inhibiting the secretion of inflammatory cytokines, such as IL-6 and the like by means of various cell lines induced by IL-17A, and can be used for preparing drugs for treating diseases involving immune-medicated inflammatory responses.

Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Disclosed herewith a separation device for performing phase separation on a three-phase liquid. The device includes: a housing; at least one pair of longitudinal baffle plates; a flow channel formed between every pair of longitudinal baffle plates; and collection chambers formed between adjacent pairs of longitudinal baffle plates. Each collection chamber is provided with a transverse baffle plate to separate the collection chamber into a first phase and a second phase collection cells. Each flow channel is provided with multiple lateral baffle plates to separate the flow channel into multiple sub-channels. In the areas of each longitudinal baffle plate where the first phase and second phase collection cells are located respectively, said longitudinal baffle plate is provided with a first and a second phase guiding holes in communication with the first phase and the second collection cells respectively.

Abstract: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Abstract: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

Abstract: The present invention relates to Fc variants with optimized Fc ligand binding properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized Fc ligand binding properties, and methods for using same.

Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.