Abstract: At least some embodiments of the present disclosure are directed to systems and methods for creating a shunt in a patient. In some embodiments, a shunting catheter includes: a catheter shaft having a distal end and a proximal end, the catheter shaft including a shaft lumen; a shunting component including one or more electrodes; and a puncture assembly disposed in the shaft lumen at a first state and extended from the catheter shaft at a second state.

Abstract: At least some embodiments of the present disclosure are directed to systems and methods for creating a shunt in a patient. In some embodiments, a shunting catheter includes a catheter shaft including a shaft lumen and a side opening, and a tissue-removal assembly disposed in the shaft lumen in a first state and including a shunting shaft being extendable from the side opening of the catheter shaft. In some examples, the shunting shaft has a curved shape when extending from the side opening to a second state. In some examples, the tissue-removal assembly includes a cutting component disposed at a distal end of the shunting shaft.

Abstract: At least some embodiments of the present disclosure are directed to systems and methods for creating a shunt in a patient. In some embodiments, a shunting catheter includes: a catheter shaft having a distal end and a proximal end, the catheter shaft including a shaft lumen; a shunting component including one or more electrodes; and a puncture assembly disposed in the shaft lumen at a first state and extended from the catheter shaft at a second state.

Abstract: Some embodiments of the present disclosure are directed to systems, apparatus, and methods for creating a shunt in a patient. In some embodiments, a shunting catheter includes an expandable ablation mechanism having a plurality of expandable struts and a plurality of positioning elements coupled to the plurality of expandable struts. The positioning elements are configured to be disposed radially outwardly from the expandable struts. The ablation mechanism is configured to receive energy from an energy source and deliver ablation energy to a target location of a patient.

Abstract: Apparatuses, systems, and methods for prosthetic valves having sensor systems are disclosed. Examples of prosthetic valves include replacement heart valves for replacing the function of a native heart valve, such as a mitral or tricuspid valve. In various embodiments, replacement heart valves are provided with sensors or markers for assisting with proper placement and/or securement in the body. A replacement heart valve may include anchors for securing the replacement heart valve to native leaflets, wherein sensors and/or markers provide feedback to the physician for confirming proper placement of the anchors during the implantation procedure. Sensors may also be used to assess the function of the prosthetic valve after deployment. Sensors may also be used to monitor blood pressure, temperature, oxygen, insulin, cholesterol, and/or glucose to assess overall patient health.

Abstract: A fixation mechanism of an implantable medical device is formed by a plurality of tines fixedly mounted around a perimeter of a distal end of the device. Each tine may be said to include a first segment fixedly attached to the device, a second segment extending from the first segment, and a third segment, to which the second segment extends. When the device is loaded in a lumen of a delivery tool and a rounded free distal end of each tine engages a sidewall that defines the lumen, to hold the tines in a spring-loaded condition, the first segment of each tine, which has a spring-biased pre-formed curvature, becomes relatively straightened, and the third segment of each tine, which is terminated by the free distal end, extends away from the axis of the device at an acute angle in a range from about 45 degrees to about 75 degrees.

Abstract: Systems, devices and methods of valvular prosthetics having one or more bioresorbable components are described. The bioresorbable components can resorb overtime, allowing the ingrowth of tissue in and around the valvular prosthetic.

Abstract: Apparatuses, systems, and methods for prosthetic valves. The prosthetic valves disclosed herein may be utilized for improved deployment, sealing, and anchoring to an implantation site. An implantation site may comprise a native heart valve or another implantation site in examples. Examples of prosthetic valves may include a proximal tensioning body positioned at a proximal portion of the prosthetic valve and a distal tensioning body positioned at a distal portion of the prosthetic valve. A sealing skirt may have a proximal end portion coupled to the proximal tensioning body and a distal end portion coupled to the distal tensioning body. The sealing skirt may be tensioned by the proximal tensioning body and the distal tensioning body and deflectable to conform to a shape of the native valve.

Abstract: A fixation mechanism of an implantable medical device is formed by a plurality of tines fixedly mounted around a perimeter of a distal end of the device. Each tine may be said to include a first segment fixedly attached to the device, a second segment extending from the first segment, and a third segment, to which the second segment extends. When the device is loaded in a lumen of a delivery tool and a rounded free distal end of each tine engages a sidewall that defines the lumen, to hold the tines in a spring-loaded condition, the first segment of each tine, which has a spring-biased pre-formed curvature, becomes relatively straightened, and the third segment of each tine, which is terminated by the free distal end, extends away from the axis of the device at an acute angle in a range from about 45 degrees to about 75 degrees.

Abstract: Some embodiments of the present disclosure are directed to systems, apparatus, and methods for creating a shunt in a patient. In some embodiments, a shunting catheter includes an expandable ablation mechanism having a plurality of expandable struts and a plurality of positioning elements coupled to the plurality of expandable struts. The positioning elements are configured to be disposed radially outwardly from the expandable struts. The ablation mechanism is configured to receive energy from an energy source and deliver ablation energy to a target location of a patient.

Abstract: Apparatuses, systems, and methods for prosthetic valves. Examples of prosthetic valves may be configured to anchor to an interior surface of a heart valve. Such prosthetic valves, in examples, may include a single frame that supports a plurality of prosthetic valve leaflets. In examples, multiple frames may be utilized to anchor to a heart valve and one or more of the frames may support a plurality of prosthetic valve leaflets.

Abstract: A prosthetic valve includes an expandable valve frame and leaflets supported therein. A plurality of elongate anchor arms extends from an outlet end portion of the valve frame. Each elongate anchor arm includes anchoring protrusions, such as barbs, for engaging surrounding tissue. During delivery to the treatment site, the anchoring protrusions face inwardly. When released from the delivery catheter, the anchoring arms evert such that the anchoring protrusions reverse orientation and face outwardly. In this position, the protrusions can engage surrounding tissue and thereby secure the prosthetic valve within a native heart valve.

Abstract: Traditional CABG procedures are performed by accessing the chest cavity and stopping the heart. However, off-pump CABG is becoming more wide-spread in use. Transcatheter CABG procedures are particularly advantageous and thus may become prevalent. A transcatheter CABG procedure can advantageously reduce complications, procedure time, and recovery time as well as providing benefits of being an off-pump, beating heart procedure. Accordingly, disclosed herein are several mechanisms and methods for accessing, implant anchoring, and visualization during a transcatheter CABG procedure.

Abstract: The present invention relates to the field of lamp technologies, and discloses a snap-in lamp structure. The snap-in lamp structure includes an inner lamp holder female socket connected to a conducting wire, and a lamp bulb. An outer lamp holder female socket including a first housing and a second housing is nested outside the inner lamp holder female socket. The first housing and the second housing each are equipped with a channel. The first housing and the second housing are matched to form an opening through which the lamp bulb is inserted. The snap-in lamp structure features the following advantages: 1. The lamp holder housing can protect the lamp holder structure and prolong the service life of the lamp. 2. The lamp holder housing is easy to produce and form. 3. The production yield can be increased and the production cost reduced. 4. The production efficiency is effectively improved.

Abstract: A device and method are described for transmitting tissue conductance communication (TCC) signals. A device may be is configured to establish a transmission window by transmitting a TCC test signal at multiple time points over a transmission test period to a receiving device and detect at least one response to the transmitted TCC test signals performed by the receiving device. The IMD is configured to establish the transmission window based on the at least one detected response so that the transmission window is correlated to a time of relative increased transimpedance between a transmitting electrode vector and receiving electrode vector during the transmission test period.

Abstract: A fixation mechanism of an implantable medical device is formed by a plurality of tines fixedly mounted around a perimeter of a distal end of the device. Each tine may be said to include a first segment fixedly attached to the device, a second segment extending from the first segment, and a third segment, to which the second segment extends. When the device is loaded in a lumen of a delivery tool and a rounded free distal end of each tine engages a sidewall that defines the lumen, to hold the tines in a spring-loaded condition, the first segment of each tine, which has a spring-biased pre-formed curvature, becomes relatively straightened, and the third segment of each tine, which is terminated by the free distal end, extends away from the axis of the device at an acute angle in a range from about 45 degrees to about 75 degrees.

Abstract: A fixation mechanism of an implantable medical device is formed by a plurality of tines fixedly mounted around a perimeter of a distal end of the device. Each tine may be said to include a first segment fixedly attached to the device, a second segment extending from the first segment, and a third segment, to which the second segment extends. When the device is loaded in a lumen of a delivery tool and a rounded free distal end of each tine engages a sidewall that defines the lumen, to hold the tines in a spring-loaded condition, the first segment of each tine, which has a spring-biased pre-formed curvature, becomes relatively straightened, and the third segment of each tine, which is terminated by the free distal end, extends away from the axis of the device at an acute angle in a range from about 45 degrees to about 75 degrees.

Abstract: A device and method are described for transmitting tissue conductance communication (TCC) signals. A device may be is configured to establish a transmission window by transmitting a TCC test signal at multiple time points over a transmission test period to a receiving device and detect at least one response to the transmitted TCC test signals performed by the receiving device. The IMD is configured to establish the transmission window based on the at least one detected response so that the transmission window is correlated to a time of relative increased transimpedance between a transmitting electrode vector and receiving electrode vector during the transmission test period.

Abstract: A fixation mechanism of an implantable medical device is formed by a plurality of tines fixedly mounted around a perimeter of a distal end of the device. Each tine may be said to include a first segment fixedly attached to the device, a second segment extending from the first segment, and a third segment, to which the second segment extends. When the device is loaded in a lumen of a delivery tool and a rounded free distal end of each tine engages a sidewall that defines the lumen, to hold the tines in a spring-loaded condition, the first segment of each tine, which has a spring-biased pre-formed curvature, becomes relatively straightened, and the third segment of each tine, which is terminated by the free distal end, extends away from the axis of the device at an acute angle in a range from about 45 degrees to about 75 degrees.

Abstract: In some examples, this disclosure describes a method for identifying a position within a patient for a first implantable medical device (IMD) to be implanted to facilitate tissue conductive communication (TCC) between the first IMD and a second IMD implanted within the patient. In some examples, the method includes storing model data that associates patient parameter data and second IMD position data with first IMD positions based on TCC communication performance, receiving patient parameter data indicating one or more anatomical or physiological parameters of the patient, receiving second IMD position data, performing analysis by at least one of comparing the model data to the patient parameter data and the second IMD position data, performing real-time computer simulations, or a combination of comparing and performing simulations, and outputting to a user an indication of the position for the first IMD to be implanted within the patient based on the analysis.