Patents by Inventor Wei-Hong Tseng

Wei-Hong Tseng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing bortezomib, intermediates, and crystalline forms thereof
    Patent number: 10934315
    Abstract: The present disclosure provides a process for preparing Bortezomib, intermediates, and crystalline forms thereof.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: March 2, 2021
    Assignee: PHARMACORE BIOTECH CO., LTD.
    Inventors: Wei-Hong Tseng, Vallapa Soong, Hsing Yu Chang, Shen Han Yang
  • PROCESS FOR PREPARING BORTEZOMIB, INTERMEDIATES, AND CRYSTALLINE FORMS THEREOF
    Publication number: 20200140464
    Abstract: The present disclosure provides a process for preparing Bortezomib, intermediates, and crystalline forms thereof.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 7, 2020
    Inventors: Wei-Hong Tseng, Vallapa Soong, Hsing Yu Chang, Shen Han Yang
  • Process for preparing cyclophosphamide, intermediates, and monohydrate thereof
    Patent number: 10479811
    Abstract: The present disclosure provides a process for preparing cyclophosphamide, intermediate, and the monohydrate thereof.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: November 19, 2019
    Assignee: PHARMACORE BIOTECH CO., LTD.
    Inventors: Wei-Hong Tseng, Vallapa Soong, Ko Hua Yu, Hsing Yu Chang, Chia-Yu Lin
  • Process for the preparation of carbapenem using cabapenem intermediates and recovery of cabapenem
    Patent number: 8729260
    Abstract: The present invention relates to an efficient process of synthesizing some known Ertapenem compounds and to provide new intermediate compounds of Meropenem and Doripenem. The process and the intermediate can substantially increase the effective yield and reduce the impurity generation. The present invention further provides a novel and effective process for recovering and purifying ertapenem compounds by utilizing a low cost, materials with chemical stability as a carrier for isolating ertapenem compounds from extracts.
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: May 20, 2014
    Assignee: Savior Lifetec Corporation
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Chia-Mao Chang, Chia-Wei Yeh, Yuan-Liang Kuo
  • Process for the preparation of antibiotic compounds
    Patent number: 8691803
    Abstract: The present invention relates to a process for the preparation of carbapenem antibiotic compounds, which are useful for intravenous and intramuscular administration.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: April 8, 2014
    Assignee: Savior Lifetec Corporation
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Shiuan-Ting Chuang
  • PROCESS FOR THE PREPARATION OF ANTIBIOTIC COMPOUNDS
    Publication number: 20120190664
    Abstract: The present invention relates to a process for the preparation of carbapenem antibiotic compounds, which are useful for intravenous and intramuscular administration.
    Type: Application
    Filed: June 24, 2011
    Publication date: July 26, 2012
    Applicant: SAVIOR LIFETEC CORPORATION
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Shiuan-Ting Chuang
  • PROCESS FOR THE PREPARATION OF ANTIBIOTIC COMPOUNDS
    Publication number: 20120190842
    Abstract: The present invention relates to a process for the preparation of carbapenem antibiotic compounds, which is useful for intravenous and intramuscular administration.
    Type: Application
    Filed: January 24, 2011
    Publication date: July 26, 2012
    Applicant: SAVIOR LIFETEC CORPORATION
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Shiuan-Ting Chuang
  • PROCESS FOR THE PREPARATION OF CARBAPENEM USING CABAPENEM INTERMEDIATES AND RECOVERY OF CABAPENEM
    Publication number: 20110288290
    Abstract: The present invention relates to preparing carbapenem intermediates that are useful to produce Ertapenem, Meropenem and Doripenem; and provides an effective process for recovering ertapenem compounds.
    Type: Application
    Filed: May 4, 2011
    Publication date: November 24, 2011
    Applicant: SAVIOR LIFETEC CORPORATION
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Chia-Mao Chang, Chia-Wei Yeh, Yuan-Liang Kuo
  • Preparation of Carbapenem Intermediate and Their Use
    Publication number: 20110288289
    Abstract: The present invention relates to preparing carbapenem intermediates that are useful to produce Ertapenem, Meropenem and Doripenem.
    Type: Application
    Filed: May 19, 2010
    Publication date: November 24, 2011
    Applicant: SAVIOR LIFETEC CORPORATION
    Inventors: Wei-Hong Tseng, Wen-Hsin Chang, Yuan-Liang Kuo, Chia-Mao Chang
  • Method for manufacturing stereoselective preparation of 4-BMA using a chiral auxiliary and chiral auxiliary
    Publication number: 20110144326
    Abstract: The present invention relates to a process for preparing (3R,4S)-3-[[[R]-1?-t-butyldimethylsilyloxy]ethyl]-4-[(R)-1?-carboxyethyl]-2-azetidinone (beta-methylazetidin-2-one; 4-BMA), a key intermediate for the synthesis of carbapenem and penem antibiotics. Specifically, the present invention relates to a process comprising first, the preparation of a chiral auxiliary from cheap L-Phenylalaninol, and then the preparation of 4-BMA in high yield and high selectivity, under industrially mild condition.
    Type: Application
    Filed: December 10, 2009
    Publication date: June 16, 2011
    Inventors: Wei-Hong Tseng, Shiuan-Ting Chuang, Zun-Yuan Hung, Ching-I Wu
  • CRYSTALLINE CARBAPENEM COMPOUND AND PRODUCED METHOD THEREOF
    Publication number: 20090216010
    Abstract: The present invention relates to a crystalline carbapenem compound and produced method thereof. The crystalline carbapenem compound of the present invention is crystalline (4R,5S,6S)-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid and it is characterized by an X-ray powder diffraction pattern of FIG. 2. The crystalline carbapenem compound of the present invention is a new crystalline form and is useful as an antibiotic agent. Furthermore, the crystalline carbapenem compound of the present invention is much more stable than carbapenem compound in a non-crystalline form. Hence, the crystalline carbapenem compound of the present invention is suitable for storage.
    Type: Application
    Filed: February 22, 2008
    Publication date: August 27, 2009
    Inventors: Wei-Hong Tseng, Yu-Lun Su, Chiung-Yi Yu
  • Asymmetric synthesis of a key intermediate for making benazepril and analogues thereof
    Patent number: 6548665
    Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: April 15, 2003
    Assignee: Scinopharm, Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, George Schloemer
  • Kinetic resolution of a intermediate useful in the production of benazepril and analogues thereof
    Publication number: 20030055245
    Abstract: The present invention provides an efficient synthetic process for making benazepril and analogues thereof by having an intermediate compound undergo epimerization and kinetic resolution.
    Type: Application
    Filed: May 21, 2002
    Publication date: March 20, 2003
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, Kau-Ming Cheng, George Schloemer, Chien-Wen Chen, Chih-Wen Cheng
  • ASYMMETRIC SYNTHESIS OF A KEY INTERMEDIATE FOR MAKING BENAZEPRIL AND ANALOGUES THEREOF
    Publication number: 20020183515
    Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.
    Type: Application
    Filed: July 19, 2001
    Publication date: December 5, 2002
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, George Schloemer