Abstract: Disclosed is a method to fabricate a multifunctional collimator structure In one embodiment, an optical collimator, includes: a dielectric layer; a substrate; and a plurality of via holes, wherein the dielectric layer is formed over the substrate, wherein the plurality of via holes are configured as an array along a lateral direction of a first surface of the dielectric layer, wherein each of the plurality of via holes extends through the dielectric layer and the substrate from the first surface of the dielectric layer to a second surface of the substrate in a vertical direction, wherein the substrate has a bulk impurity doping concentration equal to or greater than 1×1019 per cubic centimeter (cm?3) and a first thickness, and wherein the bulk impurity doping concentration and the first thickness of the substrate are configured so as to allow the optical collimator to filter light in a range of wavelengths.

Abstract: An embodiment method includes: forming a semiconductor liner layer on exposed surfaces of a fin structure that extends above a dielectric isolation structure disposed over a substrate; forming a first capping layer to laterally surround a bottom portion of the semiconductor liner layer; forming a second capping layer over an upper portion of the semiconductor liner layer; and annealing the fin structure having the semiconductor liner layer, the first capping layer, and the second capping layer thereon, the annealing driving a dopant from the semiconductor liner layer into the fin structure, wherein a dopant concentration profile in a bottom portion of the fin structure is different from a dopant concentration profile in an upper portion of the fin structure.

Abstract: Disclosed is a method to fabricate a multifunctional collimator structure In one embodiment, an optical collimator, includes: a dielectric layer; a substrate; and a plurality of via holes, wherein the dielectric layer is formed over the substrate, wherein the plurality of via holes are configured as an array along a lateral direction of a first surface of the dielectric layer, wherein each of the plurality of via holes extends through the dielectric layer and the substrate from the first surface of the dielectric layer to a second surface of the substrate in a vertical direction, wherein the substrate has a bulk impurity doping concentration equal to or greater than 1×1019 per cubic centimeter (cm?3) and a first thickness, and wherein the bulk impurity doping concentration and the first thickness of the substrate are configured so as to allow the optical collimator to filter light in a range of wavelengths.

Abstract: An embodiment method includes: forming a semiconductor liner layer on exposed surfaces of a fin structure that extends above a dielectric isolation structure disposed over a substrate; forming a first capping layer to laterally surround a bottom portion of the semiconductor liner layer; forming a second capping layer over an upper portion of the semiconductor liner layer; and annealing the fin structure having the semiconductor liner layer, the first capping layer, and the second capping layer thereon, the annealing driving a dopant from the semiconductor liner layer into the fin structure, wherein a dopant concentration profile in a bottom portion of the fin structure is different from a dopant concentration profile in an upper portion of the fin structure.

Abstract: A semiconductor device includes a semiconductor substrate having a first lattice constant, a fin-shape base protruding from the semiconductor substrate and extending lengthwise in a first direction, nanostructures suspended above the fin-shape base, a metal gate structure wrapping around each of the nanostructures, an epitaxial feature abutting the nanostructures, and inner spacers interposing the epitaxial feature and the metal gate structure. In a cross section perpendicular to the first direction the fin-shape base includes a first layer and a second layer over the first layer. The first layer has a second lattice constant different from the first lattice constant, and the second layer has a third lattice constant different from the second lattice constant. A portion of the metal gate structure is sandwiched between the second layer and a bottommost one of the nanostructures.

Abstract: The present invention relates to multi-ribozymes and their use to target RNA in a tissue-specific, target RNA-specific, or pathogen-specific manner for the treatment of cancers, proliferative disease, and bacterial, parasitic and viral infections. More specifically, the present invention relates to the use of virions and viral vectors to package and deliver DNA encoding the multi-ribozymes to a host. The present invention relates to the use of liposomes and lipid-DNA complexes to deliver DNA encoding ribozymes to a host. Most specifically, the invention relates to the use of target specific virions to package and deliver DNA comprising a target specific promoter and encoding a ribozyme(s) directed to the target organism nucleic acids. The present invention further relates to a novel vectors encoding a multi-ribozyme structure with enhanced 5? and/or 3? autocatalytically cleaving ribozymes.

Abstract: The invention provides methods and materials related to treating HPV infections (e.g., HPV infections of cutaneous and mucosal epithelial cells) and HPV-associated conditions (e.g., cervical dysplasia, HPV-associated cervical carcinomas, oral mucosal papilloma cancers, laryngeal papilloma cancers).

Abstract: The invention provides isolated nucleic acids. For example, the invention provides isolated nucleic acids having at least one strand with both sense and antisense sequences that are complementary to each other. The invention also provides isolated nucleic acids having at least one strand that is a template for both sense and antisense sequences that are complementary to each other. In addition, the invention provides cells, viruses, and transgenic animals (e.g., transgenic non-human animals) containing one or more of the isolated nucleic acids provided herein as well as methods for using one or more of the isolated nucleic acids provided herein to reduce the level of an RNA (e.g., an mRNA) within a cell.

Abstract: An electrical connector includes a main board (5) with a first card edge connector (1) mounted thereon, a sub-board (6) with a second card edge connector (2) mounted thereon, and a pair of complementary board to board connectors (3, 4) mounted on the main board (5) and the sub-board (6) respectively. The first and second card edge connectors (1, 2) are aligned with each other in a vertical direction and the second card edge connector (2) is on top of the first card edge connector (1).

Abstract: The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or pathogen infected cells in order to treat and/or eradicate the infection. In particular, the present invention relates to toxic agents which target bacteria at different stages of the bacterial life cycle, which are delivered alone or in combination to bacteria or bacteria-infected cells. The invention relates to toxic agents which are lethal to diseased cells and methods for targeting such toxic agents to a diseased cell in order to treat and/or eradicate the disease. The present invention relates to promoter elements which are pathogen-specific or tissue-specific and the use of such promoter elements to achieve pathogen-specific or tissue-specific expression of the toxic agent(s) and/or ribozyme(s) of the present invention.

Abstract: An electrical connector includes a main board (5) with a first card edge connector (1) mounted thereon, a sub-board (6) with a second card edge connector (2) mounted thereon, and a pair of complementary board to board connectors (3, 4) mounted on the main board (5) and the sub-board (6) respectively. The first and second card edge connectors (1, 2) are aligned with each other in a vertical direction and the second card edge connector (2) is on top of the first card edge connector (1).

Abstract: The invention provides isolated nucleic acids. For example, the invention provides isolated nucleic acids having at least one strand with both sense and antisense sequences that are complementary to each other. The invention also provides isolated nucleic acids having at least one strand that is a template for both sense and antisense sequences that are complementary to each other. In addition, the invention provides cells, viruses, and transgenic animals (e.g., transgenic non-human animals) containing one or more of the isolated nucleic acids provided herein as well as methods for using one or more of the isolated nucleic acids provided herein to reduce the level of an RNA (e.g., an mRNA) within a cell.

Abstract: An electrical connector comprises an insulative housing, front and rear channels in the insulative housing and a hollow space defined between the front and corresponding rear channel, a plurality of front and rear contacts received respectively in said front and rear channels, said hollow space defines at least one block for separating the front and the rear contacts from each other, and avoid the front and rear contacts contacting each other for assuring the stable transmission of the signal.

Abstract: The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or pathogen infected cells in order to treat and/or eradicate the infection. In particular, the present invention relates to toxic agents which target bacteria at different stages of the bacterial life cycle, which are delivered alone or in combination to bacteria or bacteria-infected cells. The invention relates to toxic agents which are lethal to diseased cells and methods for targeting such toxic agents to a diseased cell in order to treat and/or eradicate the disease. The present invention relates to promoter elements which are pathogen-specific or tissue-specific and the use of such promoter elements to achieve pathogen-specific or tissue-specific expression of the toxic agent(s) and/or ribozyme(s) of the present invention.

Abstract: An electrical connector adapted for mounting on a Printed Circuit Board (PCB), comprises an insulative housing, a plurality of terminals loaded in the insulative housing and a board lock device assembled in the insulative housing. The insulative housing comprises a base portion having a PCB mounting face and a mating portion extending from the base portion. The base portion defines a boardlock-receiving cavity and is formed with a block adjacent to the cavity. The board lock device comprises a retaining plate retained in the cavity and substantially parallel to the PCB mounting face of the base portion and a lock plate perpendicularly extending from the retaining plate beyond the PCB mounting face of the base portion for locking with the PCB. The retaining plate is supported by the block for preventing the board lock device from moving along a direction perpendicular to the PCB mounting face of the base portion.

Abstract: The invention provides methods and materials related to treating HPV infections (e.g., HPV infections of cutaneous and mucosal epithelial cells) and HPV-associated conditions (e.g., cervical dysplasia, HPV-associated cervical carcinomas, oral mucosal papilloma cancers, laryngeal papilloma cancers).

Abstract: An electrical connector adapted for mounting on a Printed Circuit Board (PCB), comprises an insulative housing, a plurality of terminals loaded in the insulative housing and a board lock device assembled in the insulative housing. The insulative housing comprises a base portion having a PCB mounting face and a mating portion extending from the base portion. The base portion defines a boardlock-receiving cavity and is formed with a block adjacent to the cavity. The board lock device comprises a retaining plate retained in the cavity and substantially parallel to the PCB mounting face of the base portion and a lock plate perpendicularly extending from the retaining plate beyond the PCB mounting face of the base portion for locking with the PCB. The retaining plate is supported by the block for preventing the board lock device from moving along a direction perpendicular to the PCB mounting face of the base portion.

Abstract: An electrical connector (1) includes a dielectric housing (10), a number of terminals (20) received in the dielectric housing and a pair of shielding plates attached to outer faces of the side walls. The dielectric housing includes a mating face, a pair of side walls extending from the mating face and a mating space in the mating face between the side walls. Each side wall includes a pair of protrusions and a recess in the outer face thereof. Each terminal includes a contact portion exposed to the mating space. Each shielding plate is formed with a retention blade engaging with the pair of protrusions and a spring tang received in the recess for preventing the shielding plate from moving away from the mating face.