Abstract: A device, including a body including a first post and a second post positioned on opposite sides of a recessed area is disclosed. An assembly including the device is disclosed. A method of using the device is also disclosed.

Abstract: A collet includes a cap, a conduit grasper, a collet bore, and a collet slot. The grasper is composed of a flexible material such that the grasper is compressible in response to an applied force. A conduit such as a column is installed in a fluidic component by passing the conduit through the collet and into a fluidic coupling device. The collet is then coupled to the fluidic coupling device so as to compress the grasper against the column, thereby securing the column in the fluidic coupling device. The conduit may then be inserted into the fluidic component, and fluidic coupling device may be coupled to the fluidic component to complete the conduit installation. The collet or at least the cap may then be removed by moving the collet or at least the cap around the column via the collet slot. The grasper may be removed via a grasper slot.

Abstract: A ferrule includes a body surrounding a bore that provides a fluid path along a central axis between a first end and a second end of the ferrule. The body includes a conical section configured for forming a sealing interface with a fitting in which the ferrule may be inserted and a sealing interface with a tube that may be inserted in the ferrule bore. The conical section includes collapse zones configured to collapse in a direction along the central axis in response to axial compression of the ferrule against the fitting. The collapse zones mitigate crushing of the ferrule against the tube. The collapse zones may be provided by a sealing region at the nose of the ferrule and annular grooves on the ferrule.

Abstract: A ferrule includes a body surrounding a bore that provides a fluid path along a central axis between a first end and a second end of the ferrule. The body includes a conical section configured for forming a sealing interface with a fitting in which the ferrule may be inserted and a sealing interface with a tube that may be inserted in the ferrule bore. The conical section includes collapse zones configured to collapse in a direction along the central axis in response to axial compression of the ferrule against the fitting. The collapse zones mitigate crushing of the ferrule against the tube. The collapse zones may be provided by a sealing region at the nose of the ferrule and annular grooves on the ferrule.

Abstract: Methods and apparatus for preventing the failure of slender syringe needles used for on column injection in gas chromatographs are disclosed. A needle holder designed to support the needle precludes bucking deflection beyond the maximum allowable value. In a preferred embodiment, the needle used is a tapered needle that has a proximal diameter and a distal diameter that is smaller that the proximal diameter. In these embodiments, the diameter of the bore through the needle holder is slightly larger than the proximal diameter to permit the full insertion of the entire needle structure. The needle holder bore diameter is sufficiently small, however, to preclude catastrophic failure due to buckling.

Abstract: A system and method are shown for performing cool, on-column sample injection into a chromatographic device having a capillary column which injection is achieved through the use of a syringe having a needle. The column diameter is minimized by the provision of an inlet assembly connected to the inlet end of the column, a sealing member disposed in the inlet assembly, for forming a fluid tight seal in the inlet end when the sample is injected onto the column to prevent the sample from escaping and for reducing the effective length of the needle at the point of insertion of the needle into the column and a guide member for reducing the effective length and for supporting the needle during insertion into the column. A temperature controller for controlling the temperature of the column in the region where the sample is injected is also disclosed. The sealing member is shown to include an elastomeric member and further the system includes a mechanism for continuously cooling the elastomeric member.

Abstract: Apparatus and methods are disclosed for performing a chromatographic separation of a given compound wherein the compound and a carrier gas are passed through an injection port and onto a column and wherein a portion of the column is contained in an oven. The apparatus and method are shown to include a first heater for heating the injection port in response to a first control signal, a first temperature sensor for sensing the temperature of the injection port and for generating a first temperature signal representative of the temperature of the injection port, a second heater for heating the oven in response to a second control signal, a second temperature sensor for sensing the temperature of the oven and for generating a second temperature signal representative of the temperature of the oven and a cooling member for simultaneously cooling the injection port and the column. The cooling member can include various conduit arrangements for directing a flow of cryogen fluid.