Abstract: Systems and methods of transferring data from memory to manage graphical output latency are provided. A device having a display receives an acoustic signal that carries a query. The device determines that a wireless controller is in a first state. The device establishes, based on receipt of the acoustic signal and the determination that the wireless controller device is in the first state, a first interaction mode for a graphical user interface rendered by the computing device for display via the display device. The device sets a prefetch parameter to a first value and prefetches the corresponding amount of electronic content items. The device establishes a second interaction mode and overrides the first value of the prefetch parameter to a second value, and prefetches a second amount of electronic content items corresponding to the second value.

Abstract: Aspects of the present disclosure relate to a molded electronic package and a method for manufacturing the same. The molded electronic package includes a first substrate, a second substrate, an electronic component arranged on the first substrate, a spring member arranged between the second substrate and the electronic component, the spring member including a first contact portion being fixated relative to the second substrate, and a second contact portion physically contacting the electronic component, and a body of solidified molding compound configured to encapsulate the electronic component and the spring member and to mutually fixate the first substrate, the second substrate, the electronic component and the spring member. The second substrate and the spring member are electrically and/or thermally conductive.

Abstract: Disclosed is a method for assessing the transduction efficiency and/or specificity of vectors at single cell level.

Abstract: A surface mount semiconductor device and method of manufacture. A semiconductor die is mounted on a first support surface; a leadframe is attached to the semiconductor die, the leadframe comprising: an electrical lead having a first lead region connected to the semiconductor die; and a second lead region distal the first lead region, wherein the second lead region is connected to a second support surface; encapsulating the semiconductor die, first support surface and the first lead region; the second lead region is severed from the second support surface to expose a lead end; and the second lead region is electro-plated with a metallic material, such that the lead end is coated with said metallic material.

Abstract: Methods of editing target nucleic acids are provided using a guide RNA and a Cas9 protein to excise exons in a target gene and where the edited gene is expressed to produce a truncated polypeptide.

Abstract: Systems and methods of transferring data from memory to manage graphical output latency are provided. A device having a display receives an acoustic signal that carries a query. The device determines that a wireless controller is in a first state. The device establishes, based on receipt of the acoustic signal and the determination that the wireless controller device is in the first state, a first interaction mode for a graphical user interface rendered by the computing device for display via the display device. The device sets a prefetch parameter to a first value and prefetches the corresponding amount of electronic content items. The device establishes a second interaction mode and overrides the first value of the prefetch parameter to a second value, and prefetches a second amount of electronic content items corresponding to the second value.

Abstract: The present application discloses methods useful for the multiplex measurement of enzymatic activities. Also disclosed are polynucleotide constructs, constructs libraries and compartments related suitable for use in the methods.

Abstract: Methods of editing target nucleic acids are provided using a guide RNA and a Cas9 protein to excise exons in a target gene and where the edited gene is expressed to produce a truncated polypeptide.

Abstract: The present invention refers to a fusion protein or a protein complex comprising a DNA binding protein (DnaBP), a nucleobase modifying protein (NMP), and a Base Excision Repair associated protein (BERAP. Also, described herein are a method of replacing a cytosine with a guanine on a DNA strand in a cell and a method of treating a subject having or suspected of having a disease or disorder.

Abstract: Systems and methods data structures queries to manage loading time of multimedia content are provided. A system receives an input audio signal from a computing device and identifies a request. The system identifies a quantized day value and a quantized time value. The system retrieves, via a lookup in a multi-dimensional matrix data structure with the quantized day value and quantized time value, signals for the quantized day value and the quantized time value. The system generates a query with the signals, and applies the query to a multimedia content data structure to identify a plurality of multimedia content items that match the plurality of signals. The system provides an indication of the plurality of multimedia content items that match the signals for the quantized day value and the quantized time value retrieved from the multi-dimensional matrix data structure.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.

Abstract: Systems and methods data structures queries to manage loading time of multimedia content are provided. A system receives an input audio signal from a computing device and identifies a request. The system identifies a quantized day value and a quantized time value. The system retrieves, via a lookup in a multi-dimensional matrix data structure with the quantized day value and quantized time value, signals for the quantized day value and the quantized time value. The system generates a query with the signals, and applies the query to a multimedia content data structure to identify a plurality of multimedia content items that match the plurality of signals. The system provides an indication of the plurality of multimedia content items that match the signals for the quantized day value and the quantized time value retrieved from the multi-dimensional matrix data structure.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.

Abstract: Systems and methods of transferring data from memory to manage graphical output latency are provided. A device having a display receives an acoustic signal that carries a query. The device determines that a wireless controller is in a first state. The device establishes, based on receipt of the acoustic signal and the determination that the wireless controller device is in the first state, a first interaction mode for a graphical user interface rendered by the computing device for display via the display device. The device sets a prefetch parameter to a first value and prefetches the corresponding amount of electronic content items. The device establishes a second interaction mode and overrides the first value of the prefetch parameter to a second value, and prefetches a second amount of electronic content items corresponding to the second value.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.

Abstract: Systems and methods of transferring data from memory to manage graphical output latency are provided. A device having a display receives an acoustic signal that carries a query. The device determines that a wireless controller is in a first state. The device establishes, based on receipt of the acoustic signal and the determination that the wireless controller device is in the first state, a first interaction mode for a graphical user interface rendered by the computing device for display via the display device. The device sets a prefetch parameter to a first value and prefetches the corresponding amount of electronic content items. The device establishes a second interaction mode and overrides the first value of the prefetch parameter to a second value, and prefetches a second amount of electronic content items corresponding to the second value.

Abstract: The present disclosure is generally related to a data processing system to coordinate parallel processing of audio queries across multiple devices. A data processing system can receive an audio input signal detected the display device and parse the audio input signal to identify an entity. The data processing system can transmit a query command to the display device to cause a multimedia content application to perform a search for the entity. The data processing system can access at least one of an address database and a multimedia content provider to identify a reference address for the entity. The data processing system can provide the reference address for the entity to cause the display device to present a content selection interface. The content selection interface can include an element for the reference address, prior to completion of the search for the entity performed by the multimedia content application.

Abstract: In one example, a method includes method comprising: receiving audio data generated by a microphone of a current computing device; identifying, based on the audio data, one or more computing devices that each emitted a respective audio signal in response to speech reception being activated at the current computing device; and selecting either the current computing device or a particular computing device from the identified one or more computing devices to satisfy a spoken utterance determined based on the audio data.