Patents by Inventor Wei LOU
Wei LOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240084051Abstract: Disclosed are support-activators and catalyst compositions comprising the support-activators for polymerizing olefins in which the support-activator includes clay heteroadduct, prepare from a colloidal phyllosilicate such as a colloidal smectite clay, which is chemically-modified with a heterocoagulation agent. By limiting the amount of heterocoagulation reagent relative to the colloidal smectite clay as described herein, the smectite heteroadduct support-activator is a porous and amorphous solid which can be readily isolated from the resulting slurry by a conventional filtration process, and which can activate metallocenes and related catalysts toward olefin polymerization. Related compositions and processes are disclosed.Type: ApplicationFiled: October 11, 2023Publication date: March 14, 2024Applicant: Formosa Plastics Corporation, U.S.A.Inventors: Michael D. Jensen, Kevin Chung, Daoyong Wang, Wei-Chun Shih, Guangxue Xu, Chih-Jian Chen, Charles R. Johnson, II, Mary Lou Cowen
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Publication number: 20230022235Abstract: The present invention provides benzamide compounds, compositions containing the benzamides, and use of the benzamides for inhibiting androgen receptor (AR) and/or aldo-keto reductase family 1 member C3 (AKR1C3). Also described herein methods for the treatment of hormone-mediated diseases and conditions, including hormone-related cancers such as castration resistant prostate cancer.Type: ApplicationFiled: May 16, 2022Publication date: January 26, 2023Applicants: The Regents of the University of California, Ohio State Innovation Foundation, The United States Government as represented by the Department of Veterans AffairsInventors: Allen C. Gao, Pui-Kai Li, Enming Xing, Xiaolin Cheng, Xiaotian Kong, Wei Lou
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Patent number: 11215617Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.Type: GrantFiled: October 16, 2019Date of Patent: January 4, 2022Assignees: The Regents of the University of California, U.S. Government Represented by the Department of Veterans AffairsInventors: Allen C. Gao, Chengfei Liu, Wei Lou, Chong-xian Pan
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Patent number: 11058971Abstract: Disclosed is an oil-water separator for offshore wind farms. The separator is arranged between an oil drain pipe and an accident oil tank, and has a cylindrical structure, and includes an oil storage compartment, a water storage compartment and a partition plate between them. The disclosure can ensure that the accident oil tank is empty under normal operating conditions so that a platform weight is reduced; and an insulation and an electric heating treatments are only performed at the oil-water separator to save insulation project quantity and energy consumption for heating; and a two-stage oil-water separation is achieved in the oil-water separator to avoid mixing oil droplets into water discharged from a water outlet.Type: GrantFiled: August 31, 2018Date of Patent: July 13, 2021Assignee: PowerChina Huadong Engineering Corporation LimitedInventors: Huafeng Yu, Haifeng Qi, Chunlin Huang, Shengxiao Zhao, Qunyi Tang, Zhenzhou Sun, Dongliang Zhang, Jianping Yuan, Xianlin Jia, Wei Lou, Baofeng Zhang
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Publication number: 20200041516Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.Type: ApplicationFiled: October 16, 2019Publication date: February 6, 2020Applicants: The Regents of the University of California, U.S. Government represented by the Department of Veterans AffairsInventors: Allen C. Gao, Chengfei Liu, Wei Lou, Chong-xian Pan
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Publication number: 20190366238Abstract: Disclosed is an oil-water separator for offshore wind farms. The separator is arranged between an oil drain pipe and an accident oil tank, and has a cylindrical structure, and includes an oil storage compartment, a water storage compartment and a partition plate between them. The disclosure can ensure that the accident oil tank is empty under normal operating conditions so that a platform weight is reduced; and an insulation and an electric heating treatments are only performed at the oil-water separator to save insulation project quantity and energy consumption for heating; and a two-stage oil-water separation is achieved in the oil-water separator to avoid mixing oil droplets into water discharged from a water outlet.Type: ApplicationFiled: August 31, 2018Publication date: December 5, 2019Inventors: Huafeng YU, Haifeng QI, Chunlin HUANG, Shengxiao ZHAO, Qunyi TANG, Zhenzhou SUN, Dongliang ZHANG, Jianping YUAN, Xianlin JIA, Wei LOU, Baofeng ZHANG
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Publication number: 20190177435Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.Type: ApplicationFiled: November 8, 2018Publication date: June 13, 2019Inventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Patent number: 10306882Abstract: A biological sample vitrification carrier and a method for freezing a biological sample are provided. Specifically, the carrier comprises a main body and a sealing cap that form a sealed frozen sample placing region. Frozen liquid circulating in a liquid circulating channel in the main body contacts with an outer surface of the frozen sample placing region and cools a biological sample in the frozen sample placing region. The biological sample vitrification carrier and the method in the present invention have the advantages of safety, nontoxicity and high vitrification and rewarming operation efficiency and have wide application prospects in the field of biological sample freezing.Type: GrantFiled: April 9, 2014Date of Patent: June 4, 2019Inventors: Wei Lou, Yanping Kuang
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Publication number: 20190085062Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, lung, breast, mouse, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervix, ovary, and/or prostate cancer.Type: ApplicationFiled: May 25, 2018Publication date: March 21, 2019Inventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Patent number: 10150818Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.Type: GrantFiled: July 13, 2015Date of Patent: December 11, 2018Assignee: Academia SinicaInventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Patent number: 9982041Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, lung, breast, mouse, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervix, ovary, and/or prostate cancer.Type: GrantFiled: January 16, 2015Date of Patent: May 29, 2018Assignee: ACADEMIA SINICAInventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Patent number: 9975965Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.Type: GrantFiled: January 30, 2016Date of Patent: May 22, 2018Assignee: ACADEMIA SINICAInventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Publication number: 20170315127Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.Type: ApplicationFiled: April 20, 2016Publication date: November 2, 2017Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: ALLEN C. GAO, CHENGFEI LIU, WEI LOU, Chong-xian Pan
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Publication number: 20160289340Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.Type: ApplicationFiled: January 30, 2016Publication date: October 6, 2016Inventors: Chi-Huey WONG, Tsui-Ling HSU, Yi-Wei LOU, Chih-Wei LIN, Shih-Chi YEH, Chung-Yi WU, Han-Chung WU, Han-Chung WU
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Publication number: 20160102151Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.Type: ApplicationFiled: July 13, 2015Publication date: April 14, 2016Inventors: Chi-Huey WONG, Tsui-Ling HSU, Yi-Wei LOU, Chih-Wei LIN, Shih-Chi YEH, Chung-Yi WU, Han-Chung WU
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Publication number: 20160057992Abstract: The present invention provides a biological sample vitrification carrier and a method for freezing a biological sample rapidly, simply, conveniently, closely and sterilely. Specifically, the carrier comprises a main body and a sealing cap. A near end of the main body and an inner bottom surface of the sealing cap are mutually sealed to form a sealed frozen sample placing region. The frozen sample placing region is provided with a frozen sample placing platform, the main body is provided with a frozen liquid circulating channel, and the sealing cap is provided with a guide hole corresponding to the frozen liquid circulating channel, so that, when the biological sample is frozen, frozen liquid circulating in the channel contacts with an outer surface of the frozen sample placing region and cools the biological sample in the frozen sample placing region.Type: ApplicationFiled: April 9, 2014Publication date: March 3, 2016Inventors: Wei LOU, Yanping KUANG
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Publication number: 20160063947Abstract: A system and method for interacting multi-screen in a car are presented. A memory of a main device is configured to form a main frame buffer corresponding to the main device and to form at least one secondary frame buffer corresponding to the at least one secondary device. The memory is further configured to form a frequently executed icon frame buffer corresponding to a frequently executed icon to store a user interface image when the controller is performing function of the frequently executed icon. A user interface is used to select a touch screen icon and frequently executed icon for the touch screen to be directed to a corresponding frame buffer and immediately display and control images in the corresponding touch screen to improve the interaction between touch screens.Type: ApplicationFiled: September 2, 2014Publication date: March 3, 2016Inventors: Wen-Jing Lin, Hsin-Chih Hung, Chih-Hung Chiang, Jen-Wei Lou, Wen-Chun Kang, Ping Liang
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Publication number: 20150344551Abstract: Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, lung, breast, mouse, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervix, ovary, and/or prostate cancer.Type: ApplicationFiled: January 16, 2015Publication date: December 3, 2015Inventors: Chi-Huey Wong, Tsui-Ling Hsu, Yi-Wei Lou, Chih-Wei Lin, Shih-Chi Yeh, Chung-Yi Wu, Han-Chung Wu
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Patent number: 5635706Abstract: A direct conversion broad band x-ray/gamma-ray photocathode having at least one layer functioning as an efficient x-ray or gamma-ray absorber and another layer functioning as an efficient transmission secondary electron emitter for providing both high detection efficiency and high spatial resolution, for use in either a radiation detection environment or an image intensification environment.Type: GrantFiled: March 27, 1996Date of Patent: June 3, 1997Assignee: CSL Opto-Electronics CorporationInventors: Yongzheng She, Fonglan Ji, Wei-Lou Cao, Meizhen Zhang, Yanhua Shih, Roger H. Schneider
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Patent number: D1013453Type: GrantFiled: September 13, 2022Date of Patent: February 6, 2024Inventors: Zechun Zhu, Wei Lou, Long Chen, Hongwei Guo