Abstract: Provided are a greenhouse automatic vine dropping robot and a vine dropping method. The vine dropping robot includes a mobile chassis, a lifting mechanism, a control cabinet, a front mechanical arm, a rear mechanical arm, an electric gripper, a light curtain sensor, and an optoelectronic switch. The control cabinet and the lifting mechanism are installed on the mobile chassis, and the two mechanical arms are fixed to a surface of a top platform of the lifting mechanism. The electric gripper is installed at a tail end of each of the two mechanical arms, the optoelectronic switch is arranged at a top end of a main shaft of the front mechanical arm, and the light curtain sensor is installed on the gripper at the tail end of the mechanical arm. The robot is suitable for greenhouse crops in the form of hooked-based vine dropping.

Abstract: A three-dimensional hot air circulation type air fryer is provided, including a fryer body and a hot air assembly arranged above the fryer body. A baking tray includes a baking tray body and a short edge formed by extending upwards from an edge of the baking tray body; the short edge and the side wall of the fryer body form a first air channel, the baking tray body and the bottom wall of the fryer body form a second air channel in communication with the first air channel; the baking tray body has a through air return port; the ratio of the width of the first air channel to the radius of the fryer body is 0.05-0.2, and the ratio of the distance between the top of the short edge and the bottom wall of the fryer body to the height of the fryer body is 0.2-0.45.

Abstract: Methods for the treatment of condition associated with bromodomain and extraterminal domain (BET) protein activity are disclosed. The methods include administering a therapeutically effective amount of a piperazine BET protein inhibitor or a piperidine BET protein inhibitor to a subject in need thereof. Piperazine BET protein inhibitors, piperidine BET protein inhibitors, and pharmaceutical compositions comprising the BET proteins inhibitors are also described.

Abstract: The present invention provides benzamide compounds, compositions containing the benzamides, and use of the benzamides for inhibiting androgen receptor (AR) and/or aldo-keto reductase family 1 member C3 (AKR1C3). Also described herein methods for the treatment of hormone-mediated diseases and conditions, including hormone-related cancers such as castration resistant prostate cancer.

Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.

Abstract: Disclosed is an oil-water separator for offshore wind farms. The separator is arranged between an oil drain pipe and an accident oil tank, and has a cylindrical structure, and includes an oil storage compartment, a water storage compartment and a partition plate between them. The disclosure can ensure that the accident oil tank is empty under normal operating conditions so that a platform weight is reduced; and an insulation and an electric heating treatments are only performed at the oil-water separator to save insulation project quantity and energy consumption for heating; and a two-stage oil-water separation is achieved in the oil-water separator to avoid mixing oil droplets into water discharged from a water outlet.

Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.

Abstract: Disclosed is an oil-water separator for offshore wind farms. The separator is arranged between an oil drain pipe and an accident oil tank, and has a cylindrical structure, and includes an oil storage compartment, a water storage compartment and a partition plate between them. The disclosure can ensure that the accident oil tank is empty under normal operating conditions so that a platform weight is reduced; and an insulation and an electric heating treatments are only performed at the oil-water separator to save insulation project quantity and energy consumption for heating; and a two-stage oil-water separation is achieved in the oil-water separator to avoid mixing oil droplets into water discharged from a water outlet.

Abstract: A biological sample vitrification carrier and a method for freezing a biological sample are provided. Specifically, the carrier comprises a main body and a sealing cap that form a sealed frozen sample placing region. Frozen liquid circulating in a liquid circulating channel in the main body contacts with an outer surface of the frozen sample placing region and cools a biological sample in the frozen sample placing region. The biological sample vitrification carrier and the method in the present invention have the advantages of safety, nontoxicity and high vitrification and rewarming operation efficiency and have wide application prospects in the field of biological sample freezing.

Abstract: The present invention provides new compositions and methods for treating prostate cancer, e.g., drug-resistant prostate cancer, such as anti-androgen drug (e.g., enzalutamide) resistant and/or castration resistant prostate cancer (CRPC). These new compositions include, but are not limited to, pharmaceutical compositions that include an AR-V7 inhibitor, such as niclosamide. Alternatively, these new compositions can include, but are not limited to, pharmaceutical compositions that include an AKR1C3 inhibitor, such as indomethacin. These new methods include, but are not limited to, methods of administering an AR-V7 inhibitor, such as niclosamide, and/or an AKR1C3 inhibitor, such as indomethacin, to treat patients having prostate cancer. The present invention also provides methods of inhibiting androgen receptor variant expression, e.g. AR-V7, and methods of killing cells expressing AR-V7.

Abstract: The present invention provides a biological sample vitrification carrier and a method for freezing a biological sample rapidly, simply, conveniently, closely and sterilely. Specifically, the carrier comprises a main body and a sealing cap. A near end of the main body and an inner bottom surface of the sealing cap are mutually sealed to form a sealed frozen sample placing region. The frozen sample placing region is provided with a frozen sample placing platform, the main body is provided with a frozen liquid circulating channel, and the sealing cap is provided with a guide hole corresponding to the frozen liquid circulating channel, so that, when the biological sample is frozen, frozen liquid circulating in the channel contacts with an outer surface of the frozen sample placing region and cools the biological sample in the frozen sample placing region.