Abstract: Systems and methods for malware containment on connection is provided. In exemplary embodiments, a malware containment method is described that performs a number of operations. The method involves redirecting network data received over a communication network to a virtual machine. The virtual machine is configured to simulate functionality of a digital device. Furthermore, the method involves analyzing of the redirected network data that including analyzing a response of the virtual machine to processing of the network data within the virtual machine to identify a malware attack. Thereafter, the method involves continuing to redirect the network data for processing by the virtual machine until expiration of a predetermined period of time without detection of malware, or continuing to redirect the network data for processing by the virtual machine beyond the predetermined period of time when malware is detected.

Abstract: Methods of determining methylation of DNA are provided.

Abstract: An asymmetric curved-surface prismatic image display optical system includes a first prism and second and third prisms respectively arranged in front of and behind the first prism. The first prism includes a light-exiting planar surface that is at an eye-adjacent side and is opposite to a light-entering planar surface of the second prism with an air gap therebetween and may serve as a reference for inspection of a free-form curved surface. The second prism has a light-exiting planar surface at the eye-adjacent side and parallel to a side planar surface of the third prism to allow an external-world image to be seen more clearly. Light from an image displaying panel first enters the first prism and is subjected to total internal reflection by the light-exiting planar surface toward the reflective curved surface to be reflected and re-directed to transmit through the second prism for image formation on a retina.

Abstract: An asymmetric curved-surface prismatic image display optical system includes a first prism and second and third prisms respectively arranged in front of and behind the first prism. The first prism includes a light-exiting planar surface that is at an eye-adjacent side and is opposite to a light-entering planar surface of the second prism with an air gap therebetween and may serve as a reference for inspection of a free-form curved surface. The second prism has a light-exiting planar surface at the eye-adjacent side and parallel to a side planar surface of the third prism to allow an external-world image to be seen more clearly. Light from an image displaying panel first enters the first prism and is subjected to total internal reflection by the light-exiting planar surface toward the reflective curved surface to be reflected and re-directed to transmit through the second prism for image formation on a retina.

Abstract: Methods, apparatuses and systems directed to an aggregate bandwidth utilization control scheme including fair share bandwidth allocation and dynamic allocation of bandwidth in response to detected traffic utilization. In one implementation, the present invention includes a weighted, fair share aggregate bandwidth allocation mechanism that dynamically responds to observed bandwidth utilization to provide unutilized or excess bandwidth to flows and partitions that require it. In another implementation, the present invention features a weighted fair share allocation scheme for hierarchical partition configurations. In other implementations, the present invention provides a per-flow target rate assignment mechanism that prevents spiraling decline of data flow rates.

Abstract: Exemplary systems and methods for detecting a communication channel of a bot. In exemplary embodiments, presence of a communication channel between a first network device and a second network device is detected. Data from the communication channel is scanned and used to determine if a suspected bot communication exists. If a bot communication is detected, then a recovery process may be initiated.

Abstract: Systems and methods for malware containment on connection is provided. In exemplary embodiments, digital devices are quarantined for a predetermined period of time upon connection to the communication network. When a digital device is quarantined, all network data transmitted by the digital device is temporarily directed to a controller which then analyzes the network data to identify unauthorized activity and/or malware within the newly connected digital device. An exemplary method to contain malware comprises detecting a digital device upon connection with a communication network, temporarily redirecting network data from the digital device, and analyzing the network data to identify malware within the digital device.

Abstract: The present invention provides method for amplifying a specific RNA molecule in a sample, the method comprising: (a) adding a poly(ribonucleotide) sequence to RNA molecules in the sample; (b) reverse transcribing the poly-adenylated RNA molecules using a reverse primer comprising a sequence that anneals to said poly(ribonucleotide) sequence; and (c) amplifying and detecting the cDNA molecule(s) using the same reverse primer and using a forward primer specific for the RNA molecule to be detected; wherein at least one of the forward and reverse primers comprises a hairpin primer. The invention also provides kits useful for practicing this method.

Abstract: Methods and reagents are provided for the rapid extraction of nucleic acids from a fixed paraffin embedded sample (e.g., a FFPET sample). In some embodiments, the methods comprise incubating one or more sections of said tissue sample in a lysis solution comprising a buffer sufficient to maintain the pH of said solution at a pH ranging from about pH 4 to about pH 9; a chaotropic agent; a chelating agent; and a detergent; where the incubating is at a temperature ranging from about 50 C to about 100 C; and recovering the nucleic acid from said lysis solution.

Abstract: Systems and methods for malware containment on connection is provided. In exemplary embodiments, digital devices are quarantined for a predetermined period of time upon connection to the communication network. When a digital device is quarantined, all network data transmitted by the digital device is temporarily directed to a controller which then analyzes the network data to identify unauthorized activity and/or malware within the newly connected digital device. An exemplary method to contain malware comprises detecting a digital device upon connection with a communication network, temporarily redirecting network data from the digital device, and analyzing the network data to identify malware within the digital device.

Abstract: Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise detecting a set of markers consisting of CRH, IGF2, KRT20, and ANXA10.

Abstract: Systems and methods for malware attack prevention are provided. Network data is copied from a communication network. It is then determined if a possible malware attack is within the copied network data. The network data is intercepted based on the determination. The network data is then analyzed to identify a malware attack.

Abstract: Exemplary systems and methods for malware attack detection and identification are provided. A malware detection and identification system can comprise a controller. The controller can comprise an analysis environment configured to transmit network data to a virtual machine, flag input values associated with the network data from untrusted sources, monitor the flagged input values within the virtual machine, identify an outcome of one or more instructions that manipulate the flagged input values, and determine if the outcome of the one or more instructions comprise an unauthorized activity.

Abstract: Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of detecting low grade bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise detecting androgen receptor (AR) and/or uroplakin 1B (UPK1B).

Abstract: Systems and methods for malware containment on connection are provided. Digital devices are quarantined for a predetermined period of time upon connection to the communication network. When a digital device is quarantined, all network data transmitted by the digital device is temporarily directed to a controller which then analyzes the network data to identify unauthorized activity and/or malware within the newly connected digital device. An exemplary method to contain malware comprises detecting a digital device upon connection with a communication network, temporarily redirecting network data from the digital device for a predetermined period of time, and analyzing the network data to identify malware within the digital device.

Abstract: Exemplary systems and methods for detecting a communication channel of a bot. In exemplary embodiments, presence of a communication channel between a first network device and a second network device is detected. Data from the communication channel is scanned and used to determine if a suspected bot communication exists. If a bot communication is detected, then a recovery process may be initiated.

Abstract: Systems and methods for malware containment and security analysis on connection are provided. Digital devices are quarantined for a predetermined period of time upon connection to the communication network. When a digital device is quarantined, all network data transmitted by the digital device is directed to a controller which then analyzes the network data to identify unauthorized activity and/or malware within the newly connected digital device. An exemplary method to contain malware includes detecting a digital device upon connection with a communication network, quarantining network data from the digital device for a predetermined period of time, transmitting a command to the digital device to activate a security program to identify security risks, and analyzing the network data to identify malware within the digital device.

Abstract: A dynamic signature creation and enforcement system can comprise a tap configured to copy network data from a communication network, and a controller coupled to the tap. The controller is configured to receive the copy of the network data from the tap, analyze the copy of the network data with a heuristic to determine if the network data is suspicious, flag the network data as suspicious based on the heuristic determination, simulate transmission of the network data to a destination device to identify unauthorized activity, generate an unauthorized activity signature based on the identification, and transmit the unauthorized activity signature to a digital device configured to enforce the unauthorized activity signature.

Abstract: A dynamic signature creation and enforcement system can comprise a tap configured to copy network data from a communication network, and a controller coupled to the tap. The controller is configured to receive the copy of the network data from the tap, analyze the copy of the network data with a heuristic to determine if the network data is suspicious, flag the network data as suspicious based on the heuristic determination, simulate transmission of the network data to a destination device to identify unauthorized activity, generate an unauthorized activity signature based on the identification, and transmit the unauthorized activity signature to a digital device configured to enforce the unauthorized activity signature.

Abstract: Methods and systems for detecting encrypted bot command and control communication channels are provided. In the exemplary method, the presence of a communication channel between a first network device and a second network device is monitored. Active and inactive periods of the network device are detected and a reverse channel is determined based on the detection. The first network device may then be flagged as potentially infected or suspected based on the reverse channel determination.