Abstract: The present disclosure belongs to the technical fields of computational medicine and clinical oncology, and specifically relates to a molecular subtyping method for gastric cancer (GC) based on metabolic genes, a construction method for a prognostic prediction model and applications. In the present disclosure, metabolic process alterations are overall assessed, and new metabolic transcription patterns based on 456 metabolic gene-related signatures are identified. Three different metabolic patterns are validated by unsupervised consensus clustering analysis and independent datasets, and molecular and clinical pathological features of these three metabolite clusters have different metabolic gene expressions, pathway enrichments, gene variations, and survival outcomes.

Abstract: Disclosed herein are methods, compositions, and reactor systems for producing difructose anhydride. The method comprises contacting a solution comprising fructose and gamma valerolactone with an acidic catalyst at an effective temperature for an effective contact time to produce difructose anhydride.

Abstract: The present disclosure relates to a system and process for separating sand and gravel in sediments of a sewage pipe network and recycling organic matters. The system includes a conveying grid plate, a mud outlet is provided below the conveying grid plate, and a masonry conveying area is provided at one side of the conveying grid plate; a fiber crushing tank, disposed below the mud outlet, and a crushing device is disposed below the mud outlet; a masonry scouring and recycling tank, provided with an interception grille located at one side of the masonry conveying area, a flushing device is disposed above the interception grille, a masonry outlet is provided in the masonry scouring and recycling tank, the masonry scouring and recycling tank is communicated with a muddy water return pipe, and the muddy water return pipe is communicated with the mud outlet.

Abstract: The disclosure belongs to the field of sewage treatment technology, in particular to a low-carbon nitrogen and phosphorus removal system and process for sewage treatment. The system of the disclosure includes a primary sedimentation fermentation tank, a mainstream modified A2O unit and a bypass anammox unit. The disclosure sets a denitrification phosphorus removal functional zone in the anoxic tank of the A2O system, and sets a deoxygenation zone in the aerobic tank. Combined with the primary sedimentation fermentation tank, the efficient utilization of the carbon source of the A2O process is strengthened. The system has good effluent quality and does not require the addition of a carbon source, and the aeration energy consumption is low, which achieves efficient and low-carbon nitrogen and phosphorus removal.

Abstract: The disclosure belongs to the field of sewage treatment technology, in particular to a low-carbon nitrogen and phosphorus removal system and process for sewage treatment. The system of the disclosure includes a primary sedimentation fermentation tank, a mainstream modified A2O unit and a bypass anammox unit. The disclosure sets a denitrification phosphorus removal functional zone in the anoxic tank of the A2O system, and sets a deoxygenation zone in the aerobic tank. Combined with the primary sedimentation fermentation tank, the efficient utilization of the carbon source of the A2O process is strengthened. The system has good effluent quality and does not require the addition of a carbon source, and the aeration energy consumption is low, which achieves efficient and low-carbon nitrogen and phosphorus removal.

Abstract: The present disclosure relates to a system and process for separating sand and gravel in sediments of a sewage pipe network and recycling organic matters. The system includes a conveying grid plate, a mud outlet is provided below the conveying grid plate, and a masonry conveying area is provided at one side of the conveying grid plate; a fiber crushing tank, disposed below the mud outlet, and a crushing device is disposed below the mud outlet; a masonry scouring and recycling tank, provided with an interception grille located at one side of the masonry conveying area, a flushing device is disposed above the interception grille, a masonry outlet is provided in the masonry scouring and recycling tank, the masonry scouring and recycling tank is communicated with a muddy water return pipe, and the muddy water return pipe is communicated with the mud outlet.

Abstract: A two-piece coupling walking beam is foldable and separable for sucker rod pumping system shipment, storage, installation, or servicing. It provides a two-piece coupling walking beam using connection plates—a pin plate, a fastening plate, and/or strengthening plate(s) for sucker rod pumping systems. A foldable walking beam with a two-piece coupling beam has a connection joint by which the portion with a horsehead located in the front end of the beam for sucker rod pumping systems wherein the walking beam can be folded either transversely (horizontally or sideways) or longitudinally (vertically) to the other portion of the beam without a horsehead to provide working space for system maintenance, installation/reinstallation, or servicing.

Abstract: A chassis housing one or more Information Handling Systems (IHSs) includes a bay for coupling hardware components to the chassis, such as rear-facing bay that extends from the chassis midplane to an externally accessible opening. A first hardware component is fastened to a removeable carrier and the carrier is inserted in the bay, with the first hardware component coupling to the midplane. The carrier includes arms that extend to the externally accessible opening. Each arm includes a retractable handle that is used, when in an extended position, to extract the carrier from the bay. A second, removeable hardware component is inserted in the bay, with the second hardware components nested between the arms of the carrier. The carrier handles rotate to a concealed position when the second hardware component is nested in the carrier and the handles rotate to the extended position when the second hardware component is removed.

Abstract: A chassis housing one or more Information Handling Systems (IHSs) includes a bay for coupling hardware components to the chassis, such as rear-facing bay that extends from the chassis midplane to an externally accessible opening. A first hardware component is fastened to a removeable carrier and the carrier is inserted in the bay, with the first hardware component coupling to the midplane. The carrier includes arms that extend to the externally accessible opening. Each arm includes a retractable handle that is used, when in an extended position, to extract the carrier from the bay. A second, removeable hardware component is inserted in the bay, with the second hardware components nested between the arms of the carrier. The carrier handles rotate to a concealed position when the second hardware component is nested in the carrier and the handles rotate to the extended position when the second hardware component is removed.

Abstract: Disclosed is a lymph targeting nuclear magnetic contrast agent using a brown algae polysaccharide as a carrier, and a preparation method and a use thereof. A macromolecular contrast agent with good water solubility was prepared by using the brown algae polysaccharide as the carrier, using mannose or mannose derivatives as a mannose receptor (MBP) recognition group, and using a paramagnetic metal ion chelate as a nuclear magnetic resonance imaging group. The binding capacity of lymphoid tissue was improved. The mannose or mannose derivative group introduced into the synthesized contrast agent molecule achieves the goal of binding to the enriched mannose receptors in the lymphoid tissues. At the same time, after the contrast agent is injected subcutaneously, both lymph vessels and lymph nodes were clearly visualized under MRI scanning.

Abstract: A method of establishing a coronary artery disease (CAD) prediction model for CAD screening includes establishing a data set in a computer equipment; entering the data set and corresponding future CAD condition of asymptomatic individuals into a machine learning component; selecting a plurality of robust variables from the clinical data and the cardiovascular markers of the cardiovascular markers panel by using feature selection methods; establishing the CAD prediction model by using machine learning methods; uploading new clinical data and new results of the cardiovascular markers to the cloud-based platform when any asymptomatic individuals undergo the health examination, and performing calculation and analysis by the CAD prediction model; and notifying the asymptomatic individuals of having a high risk of encountering a CAD event or not in a certain period of follow-up time.

Abstract: A two-piece coupling walking beam is foldable and separable for sucker rod pumping system shipment, storage, installation, or servicing. It provides a two-piece coupling walking beam using connection plates—a pin plate, a fastening plate, and/or strengthening plate(s) for sucker rod pumping systems. A foldable walking beam with a two-piece coupling beam has a connection joint by which the portion with a horsehead located in the front end of the beam for sucker rod pumping systems wherein the walking beam can be folded either transversely (horizontally or sideways) or longitudinally (vertically) to the other portion of the beam without a horsehead to provide working space for system maintenance, installation/reinstallation, or servicing.

Abstract: A method for preparing a porous organic framework-supported atomic noble metal catalyst for catalytic oxidation of VOCs at room temperature, including: (1) adding 2,6-diaminopyridine and 1,3,5-benzenetricarboxylic acid chloride to a triethylamine-containing dichloromethane solution and stirring the reaction mixture; reacting the reaction mixture in an oil bath under heating to produce a porous pyridine-amide framework; (2) impregnating the porous pyridine-amide framework completely in a noble metal salt solution followed by ultrasonication and standing; reducing the porous organic framework-supported noble metal ions with sodium borohydride solution; washing and drying to produce a semi-finished porous pyridine-amide framework-supported atomic noble metal catalyst; (3) calcining the semi-finished catalyst in a muffle furnace to obtain a finished catalyst. The catalyst provided herein has high atomic dispersion and atomic active sites, significantly improving the catalytic efficiency.

Abstract: A mechanism of a semiconductor structure with composite barrier layer under redistribution layer is provided. A semiconductor structure includes a substrate comprising a top metal layer on the substrate; a passivation layer over the top metal layer having an opening therein exposing the top metal layer; a composite barrier layer over the passivation layer and the opening, the composite barrier layer includes a center layer, a bottom layer, and an upper layer, wherein the bottom layer and the upper layer sandwich the center layer; and a redistribution layer (RDL) over the composite barrier layer and electrically connecting the underlying top metal layer.

Abstract: A mechanical arm and an operation method thereof, a mechanical arm device and a manufacturing equipment of a display panel are disclosed. The mechanical arm includes an arm main body, a bearing section and a first driver. The bearing section is arranged at a first end of the arm main body, and is movably connected with the first end of the arm main body, the bearing section includes a first bearing surface; and the first driver is arranged at the first end of the arm main body, and is connected with the bearing section to drive the bearing section at least to rotate parallel to the first bearing surface.

Abstract: A coronary artery disease (CAD) screening method includes 1) collecting clinical information of asymptomatic individuals and testing a plurality of samples of the individuals by using a cardiovascular markers panel including a plurality of cardiovascular markers; 2) entering the clinical information and the test results and the corresponding CAD states of the individuals into a machine learning platform; 3) selecting a plurality of roust variables from the clinical information and the cardiovascular markers of the cardiovascular markers panel by using feature selection methods; 4) using a machine learning algorithm embedded in the machine learning platform to establish a CAD prediction model; and 5) entering clinical information and sample data obtained by using the cardiovascular markers panel for an individual being screened into the CAD prediction model for calculation and analysis, thereby determining whether the individual being screened has CAD or not.

Abstract: A mechanical arm and an operation method thereof, a mechanical arm device and a manufacturing equipment of a display panel are disclosed. The mechanical arm includes an arm main body, a bearing section and a first driver. The bearing section is arranged at a first end of the arm main body, and is movably connected with the first end of the arm main body, the bearing section includes a first bearing surface; and the first driver is arranged at the first end of the arm main body, and is connected with the bearing section to drive the bearing section at least to rotate parallel to the first bearing surface.

Abstract: Disclosed is a lymph targeting nuclear magnetic contrast agent using a brown algae polysaccharide as a carrier, and a preparation method and a use thereof. A macromolecular contrast agent with good water solubility was prepared by using the brown algae polysaccharide as the carrier, using mannose or mannose derivatives as a mannose receptor (MBP) recognition group, and using a paramagnetic metal ion chelate as a nuclear magnetic resonance imaging group. The binding capacity of lymphoid tissue was improved. The mannose or mannose derivative group introduced into the synthesized contrast agent molecule achieves the goal of binding to the enriched mannose receptors in the lymphoid tissues.

Abstract: A mechanism of a semiconductor structure with composite barrier layer under redistribution layer is provided. A semiconductor structure includes a substrate comprising a top metal layer on the substrate; a passivation layer over the top metal layer having an opening therein exposing the top metal layer; a composite barrier layer over the passivation layer and the opening, the composite barrier layer includes a center layer, a bottom layer, and an upper layer, wherein the bottom layer and the upper layer sandwich the center layer; and a redistribution layer (RDL) over the composite barrier layer and electrically connecting the underlying top metal layer.