Patents by Inventor WEI-TING KAO

WEI-TING KAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240228587
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Application
    Filed: September 26, 2023
    Publication date: July 11, 2024
    Inventors: Chang-Yi Wang, Wen-Jiun Peng, Wei-Ting Kao
  • Publication number: 20240191000
    Abstract: A high concentration antibody formulation comprising an antibody at a concentration of about 120-200 mg/ml, a histidine buffer at a concentration of about 5-15 mM, an amino acid at a concentration of about 1-1.5% (w/v), a tonicity modifier such as sodium chloride at a concentration of about 50-100 mM; and a non-ionic surfactant such as polysorbate 80 at a concentration of about 0.005-0.02% (w/v). In some instances, the high concentration antibody formulation may have a pH of about 5.5 to 6.5.
    Type: Application
    Filed: April 1, 2022
    Publication date: June 13, 2024
    Applicant: ONENESS BIOTECH CO., LTD.
    Inventors: Nien-Yi CHEN, Wei-Ting KAO
  • Publication number: 20240182545
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Application
    Filed: September 26, 2023
    Publication date: June 6, 2024
    Inventors: Chang-Yi Wang, Wen-Jiun Peng, Wei-Ting Kao
  • Publication number: 20240132572
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Application
    Filed: September 25, 2023
    Publication date: April 25, 2024
    Inventors: Chang-Yi Wang, Wen-Jiun Peng, Wei-Ting Kao
  • Patent number: 11820807
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: November 21, 2023
    Inventors: Chang-Yi Wang, Wen-Jiun Peng, Wei-Ting Kao
  • Publication number: 20160362474
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Application
    Filed: June 9, 2016
    Publication date: December 15, 2016
    Inventors: Chang-Yi WANG, Wen-Jiun PENG, Wei-Ting KAO
  • Publication number: 20160362473
    Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.
    Type: Application
    Filed: January 20, 2016
    Publication date: December 15, 2016
    Inventors: CHANG-YI WANG, WEN-JIUN PENG, WEI-TING KAO