Abstract: The present disclosure provides a method for reducing uric acid by using Lactobacillus paracasei LT12 or Lactobacillus plantarum CBT LP3. The technical schemes provided herein produces the efficacies in reducing uric acid and protecting kidneys, wherein Lactobacillus paracasei LT12 and Lactobacillus plantarum CBT LP3 can effectively degrade inosine and guanosine and reduce production of uric acid, serum creatinine, and blood urea nitrogen; reducing renal pro-inflammatory factor levels; decreasing oxidative damage caused by uric acid production; and promoting uric acid excretion. Mice experiments prove that mice with high uric acid levels, after continuous consumption of the composition of the present invention, have significantly lowered blood uric acid levels. In addition, compared to control group, renal damage is significantly reduced, indicating an improved efficacy in renal protection.

Abstract: The present invention provides an edible composition for alleviating visual fatigue. The composition comprises in parts by weight 1 to 10 parts of curcuma powder, 1 to 12 parts of whole coffee fruit extract, 1 to 20 parts of phospholipid composite, 1 to 15 parts of DHA, 0.5 to 5 parts of phosphatidylserine, and 0.1 to 5 parts of vitamin C. After one week of trial consumption by the subject, the duration of photopic vision is improved with a significant difference in comparison with that before the trial; after 2 weeks of trial consumption, the overall score of visual fatigue symptoms decreases with a significant difference in comparison with that before the trial; after 8 weeks of trial consumption by the subject, the vision field thereof is remarkably enlarged, indicating the formulation may prevent the occurrence of glaucoma. The coffee extract combined with the remaining ingredients has a synergistic effect.

Abstract: The present invention provides an edible composition for promoting hair growth and delaying hair graying. The composition comprises in parts by weight: 2 to 30 parts of nucleoprotein peptides, 1 to 25 parts of whole coffee fruit extract, 5 to 60 parts of yeast composite powder and 10 to 55 parts of collagen. The edible composition for promoting hair growth and delaying hair graying provided by the present invention can promote hair growth, with a significant change in fine hair after 1 week of consumption and a 2 to 3 times increase in fine hair after 8 weeks of consumption, a significant reduction in the percentage of grey hair after 2 weeks of consumption, and a 10% to 40% reduction in the percentage of grey hair after 8 weeks of consumption. It also has an effect in skin improvement.

Abstract: The invention provides a method of extracting whole coffee fruit, an extract obtained from the method, and method of ameliorating age-related neurodegenerative diseases using said extract. The whole coffee fruit extract may be extracted by water, methanol, ethanol, or acetone and may comprise chlorogenic acid (CA) and procyanidine. The expression levels of p-CREB, BDNF, p-eIF2?, BACE-1, A?, NLRP3, caspase-1, IL-1? and COX-2 which may relate to age-related neurodegenerative diseases can be modulated.