Abstract: A silicone monomer synthesis device with a built-in separation assembly is disclosed, and includes a device main body, a separation assembly, a return assembly, and a gas outlet pipe. The device main body is internally provided with the separation assembly, particles separated by the separation assembly can return to a reaction zone main cylinder through the return assembly, and a purified gas is discharged from a reactor cylinder through the gas outlet pipe.

Abstract: Provided are a genetically modified cell line producing a recombinant glycoprotein having a mannose-terminated N-glycan and a method for producing the recombinant glycoprotein or a method for generating the cell, clone or cell line. The cell line comprises an insertion of less than 600 bp in the coding region of a chromosomal sequence encoding MGAT1.

Abstract: Methods and systems are provided for troubleshooting anomalies in a high-voltage bus system for an electrified vehicle are provided herein. The high-voltage bus system being electrically connected to a plurality of electrical components such that each electrical component in the plurality of electrical components has a similar voltage when the high-voltage bus system is electrified. The method includes detecting individual voltages for each electrical component in the plurality of electrical components using a voltage sensor of each of the electrical components in the plurality of electrical components; determining a baseline voltage for each of the electrical components in the plurality of electrical components, the baseline voltage corresponding to at least a subset of the individual voltages; and comparing any one of the individual voltages to the baseline voltage to determine if that individual voltage is anomalous.

Abstract: Provided are a genetically modified cell line producing a recombinant glycoprotein having a mannose-terminated N-glycan and a method for producing the recombinant glycoprotein or a method for generating the cell, clone or cell line. The cell line comprises an insertion of less than 600 bp in the coding region of a chromosomal sequence encoding MGAT1.

Abstract: Disclosed are a method and device for preventing carbon deposition in a fluidized bed reactor for the organosilicon monomer synthesis. The device includes a tank, at least one U-shaped heat exchange tube, and at least one upper flow-guide block. The U-shaped heat exchange tube includes an elbow portion, and is arranged vertically with the elbow portion at a lower end. The upper flow-guide block is arranged on an upper surface of the elbow portion. A width of the upper flow-guide block decreases from an end connected to the elbow portion to an end away from the elbow portion.

Abstract: A method, controller, and internal combustion engine including the controller and operable in accordance with the method by: determining a temperature of a working liquid in an engine block circuit (31, 35) of the internal combustion engine (10), the working liquid comprising a cooling liquid or a lubrication liquid; operating the internal combustion engine (10); engaging a thermal load responsive to the temperature of the liquid being below a first temperature threshold, wherein engaging the thermal load comprises at least one of increasing a pumping load of the internal combustion engine (10), or changing an air/fuel ratio, thereby adding heat to the engine block circuit (31, 35); controlling the thermal load as a function of the temperature of the liquid; and disengaging at least a portion of the thermal load responsive to the temperature of the liquid being above the low temperature limit.

Abstract: Antibodies specific for secretogranin III (Scg3) are disclosed. Methods of using the antibodies, antigen-binding fragments thereof, or pharmaceutical compositions comprising the same in the treatment of diseases such as diabetic retinopathy, neovascular age-related macular degeneration, retinopathy of prematurity, and cancer, are also disclosed.

Abstract: Antibodies specific for secretogranin III (Scg3) are disclosed. Methods of using the antibodies, antigen-binding fragments thereof, or pharmaceutical compositions comprising the same in the treatment of diseases such as diabetic retinopathy, neovascular age-related macular degeneration, retinopathy of prematurity, and cancer, are also disclosed.

Abstract: A system can include an engine, an aftertreatment system with a particulate filter, and a controller. The controller is configured to compare a time value since a last delta pressure soot load estimate process to a predetermined time threshold. Responsive to the time value being greater than or equal to the predetermined time threshold, the controller decreases a flow threshold value to a lower flow threshold value. If the flow amount is greater than or equal to the lower flow threshold value, then the controller activates a delta pressure soot load estimation process. A combined soot load estimate is then calculated using a delta pressure soot load estimation of the delta pressure soot load estimate process responsive to the lower flow threshold value.

Abstract: A method, controller, and internal combustion engine including the controller and operable in accordance with the method by: determining a temperature of a working liquid in an engine block circuit (31, 35) of the internal combustion engine (10), the working liquid comprising a cooling liquid or a lubrication liquid; operating the internal combustion engine (10); engaging a thermal load responsive to the temperature of the liquid being below a first temperature threshold, wherein engaging the thermal load comprises at least one of increasing a pumping load of the internal combustion engine (10), or changing an air/fuel ratio, thereby adding heat to the engine block circuit (31, 35); controlling the thermal load as a function of the temperature of the liquid; and disengaging at least a portion of the thermal load responsive to the temperature of the liquid being above the low temperature limit.

Abstract: Antibodies specific for secretogranin III (Scg3) are disclosed. Methods of using the antibodies, antigen-bin ding fragments thereof, or pharmaceutical compositions comprising the same in the treatment of diseases such as diabetic retinopathy, neovascular age-related macular degeneration, retinopathy of prematurity, and cancer, are also disclosed.

Abstract: A system can include an engine, an aftertreatment system with a particulate filter, and a controller. The controller is configured to compare a time value since a last delta pressure soot load estimate process to a predetermined time threshold. Responsive to the time value being greater than or equal to the predetermined time threshold, the controller decreases a flow threshold value to a lower flow threshold value. If the flow amount is greater than or equal to the lower flow threshold value, then the controller activates a delta pressure soot load estimation process. A combined soot load estimate is then calculated using a delta pressure soot load estimation of the delta pressure soot load estimate process responsive to the lower flow threshold value.

Abstract: A system can include an engine, an aftertreatment system with a particulate filter, and a controller. The controller is configured to compare a time value since a last delta pressure soot load estimate process to a predetermined time threshold. Responsive to the time value being greater than or equal to the predetermined time threshold, the controller decreases a flow threshold value to a lower flow threshold value. If the flow amount is greater than or equal to the lower flow threshold value, then the controller activates a delta pressure soot load estimation process. A combined soot load estimate is then calculated using a delta pressure soot load estimation of the delta pressure soot load estimate process responsive to the lower flow threshold value.

Abstract: A system can include an engine, an aftertreatment system with a particulate filter, and a controller. The controller is configured to compare a time value since a last delta pressure soot load estimate process to a predetermined time threshold. Responsive to the time value being greater than or equal to the predetermined time threshold, the controller decreases a flow threshold value to a lower flow threshold value. If the flow amount is greater than or equal to the lower flow threshold value, then the controller activates a delta pressure soot load estimation process. A combined soot load estimate is then calculated using a delta pressure soot load estimation of the delta pressure soot load estimate process responsive to the lower flow threshold value.

Abstract: According to one representative embodiment, an apparatus for controlling reductant dosing in an SCR catalyst system having a reductant injection system configured to inject reductant into an exhaust gas stream includes a controller, an actual reductant dosing rate module, and a reductant doser compensation module. The controller is configured to determine a reductant dosing rate command representing a desired reductant dosing rate. The actual reductant dosing rate module is configured to determine a predicted actual reductant dosing rate based at least partially on the reductant dosing rate command. The reductant doser compensation module is configured to determine a modified reductant dosing rate command based at least partially on the predicted actual reductant dosing rate. The reductant injection system injects reductant into the exhaust gas stream at a rate corresponding to the modified reductant dosing rate command.

Abstract: According to one representative embodiment, an apparatus for reducing NOx emissions in an engine exhaust gas stream of an engine system having a selective catalytic reduction (SCR) system with an SCR catalyst positioned downstream of a reductant injector includes a NOx reduction target module and a reductant module. The NOx reduction target module is configured to determine a NOx reduction requirement, which includes an amount of NOx in the exhaust gas stream to be reduced on the SCR catalyst. The reductant module is configured to determine the amount of reductant added to the exhaust gas stream to achieve the NOx reduction requirement. The amount of reductant added to the exhaust gas stream is a function of at least one ammonia storage characteristic of the SCR catalyst, at least one reductant-to-ammonia conversion characteristic, and a conversion capability of an AMOX catalyst in exhaust receiving communication with the SCR catalyst.

Abstract: Various embodiments of an apparatus, system, and method are disclosed for reducing NOx emissions using ammonia storage on an SCR catalyst. For example, according to one representative embodiment, an apparatus for reducing NOx emissions in an engine exhaust includes a NOx reduction target module that is configured to determine a NOx reduction requirement. The apparatus also includes an ammonia storage module that is configured to determine an ammonia storage modifier. An ammonia target module of the apparatus is configured to determine an ammonia addition requirement. The ammonia target module is communicable in data receiving communication with the ammonia storage module to receive the ammonia storage modifier, which is added to the ammonia addition requirement. The apparatus also includes a reductant target module that is configured to determine a reductant injection requirement that includes an amount of reductant added to the exhaust gas stream to achieve the ammonia addition requirement.

Abstract: Various embodiments of an apparatus, system, and method are disclosed for reducing NOx emissions on an SCR catalyst. For example, according to one representative embodiment, an apparatus for reducing NOx emissions in an engine exhaust includes a NOx reduction target module that is configured to determine a NOx reduction requirement that includes an amount of NOx in the exhaust gas stream to be reduced on a selective catalytic reduction (SCR) catalyst. The apparatus also includes an ammonia target module that is configured to determine an ammonia addition requirement that includes an amount of ammonia added to the exhaust gas stream to achieve the NOx reduction requirement. The apparatus also includes a reductant target module that is configured to determine a reductant injection requirement that includes an amount of reductant added to the exhaust gas stream to achieve the ammonia addition requirement.

Abstract: According to one representative embodiment, an apparatus for controlling reductant dosing in an SCR catalyst system having a reductant injection system configured to inject reductant into an exhaust gas stream includes a controller, an actual reductant dosing rate module, and a reductant doser compensation module. The controller is configured to determine a reductant dosing rate command representing a desired reductant dosing rate. The actual reductant dosing rate module is configured to determine a predicted actual reductant dosing rate based at least partially on the reductant dosing rate command. The reductant doser compensation module is configured to determine a modified reductant dosing rate command based at least partially on the predicted actual reductant dosing rate. The reductant injection system injects reductant into the exhaust gas stream at a rate corresponding to the modified reductant dosing rate command.

Abstract: According to one representative embodiment, an apparatus for reducing NOx emissions in an engine exhaust gas stream of an engine system having a selective catalytic reduction (SCR) system with an SCR catalyst positioned downstream of a reductant injector includes a NOx reduction target module and a reductant module. The NOx reduction target module is configured to determine a NOx reduction requirement, which includes an amount of NOx in the exhaust gas stream to be reduced on the SCR catalyst. The reductant module is configured to determine the amount of reductant added to the exhaust gas stream to achieve the NOx reduction requirement. The amount of reductant added to the exhaust gas stream is a function of at least one ammonia storage characteristic of the SCR catalyst, at least one reductant-to-ammonia conversion characteristic, and a conversion capability of an AMOX catalyst in exhaust receiving communication with the SCR catalyst.