Patents by Inventor Wei Xia Ang

Wei Xia Ang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gamma delta T cells and a method of augmenting the tumoricidal activity of the same
    Patent number: 11629333
    Abstract: The present invention relates to a method of generating ?? T cells having at least one down-regulated co-inhibitory receptor, the method comprising the steps of: (a) culturing a population of cells comprising ?? T cells with a phosphoantigen to expand the ?? T cells; and (b) culturing the expanded ?? T cells with artificial antigen-presenting cells expressing a Fc receptor, and an anti-CD3 antibody. The present invention also relates to ?? T cells generated according to a method of the present invention, as well as methods of treatment and medical uses thereof.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: April 18, 2023
    Assignee: Agency for Science, Technology and Research
    Inventors: Shu Wang, Wei Xia Ang, Jieming Zeng
  • GAMMA DELTA T CELLS AND A METHOD OF AUGMENTING THE TUMORICIDAL ACTIVITY OF THE SAME
    Publication number: 20200032207
    Abstract: The present invention relates to a method of generating ?? T cells having at least one down-regulated co-inhibitory receptor, the method comprising the steps of: (a) culturing a population of cells comprising ?? T cells with a phosphoantigen to expand the ?? T cells; and (b) culturing the expanded ?? T cells with artificial antigen-presenting cells expressing a Fc receptor, and an anti-CD3 antibody. The present invention also relates to ?? T cells generated according to a method of the present invention, as well as methods of treatment and medical uses thereof.
    Type: Application
    Filed: February 8, 2018
    Publication date: January 30, 2020
    Inventors: Shu Wang, Wei Xia Ang, Jieming Zeng