Patents by Inventor Wei-Xing Guo

Wei-Xing Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF SCREENING FOR RISK OF PROLIFERATIVE DISEASE AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASE
    Publication number: 20120052504
    Abstract: A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
    Type: Application
    Filed: August 22, 2011
    Publication date: March 1, 2012
    Inventors: Rose-Mary N. Boustany, Wei-Xing Guo, Andrea Amalfitano
  • Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
    Patent number: 8003327
    Abstract: A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: August 23, 2011
    Assignee: Duke University
    Inventors: Rose-Mary N. Boustany, Wei-Xing Guo, Andrea Amalfitano
  • METHODS OF SCREENING FOR RISK OF PROLIFERATIVE DISEASE AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASE
    Publication number: 20090253137
    Abstract: A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
    Type: Application
    Filed: January 22, 2009
    Publication date: October 8, 2009
    Inventors: Rose-Mary N. Boustany, Wei-Xing Guo, Andrea Amalfitano
  • Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
    Publication number: 20070054302
    Abstract: A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
    Type: Application
    Filed: September 21, 2006
    Publication date: March 8, 2007
    Inventors: Rose-Mary Boustany, Wei-Xing Guo, Andrea Amalfitano
  • Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
    Patent number: 7129043
    Abstract: A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
    Type: Grant
    Filed: October 21, 1999
    Date of Patent: October 31, 2006
    Assignee: Duke University
    Inventors: Rose-Mary N. Boustany, Wei-Xing Guo, Andrea Amalfitano