Abstract: A crystalline form of a high-stability nor-ursodeoxycholic berberine salt and a preparation method therefor are provided. The crystalline form has the following structural formula. In X-ray powder diffraction of the crystalline form, a 2? diffraction angle has characteristic peaks at 3.54+/?0.2 degrees, 7.13+/?0.2 degrees, 13.14+/?0.2 degrees, 15.95+/?0.2 degrees, 16.40+/?0.2 degrees, 18.64+/?0.2 degrees, 24.90+/?0.2 degrees, 25.76+/?0.2 degrees and 26.30+/?0.2 degrees.

Abstract: An artificial combined rhizosphere nitrogen fixation system includes a recombinant nitrogen-fixing engineering bacterium, which is transformed with genes for encoding a nitrogen fixation activator Neb and an ammonium transporter amtR, and a recombinant plant, which is transformed with a gene for encoding an ammonium-affiliated protein Ham. The coupling of the functions of the above two is achieved through a seed-coated inoculation at a rhizosphere of a crop.

Abstract: Disclosed are a method, an apparatus, and an electronic device for determining a heart valve based on multiple planes. The method includes steps of: determining a plurality of target planes in a heart based on an anatomical image; determining at least one first initial pushing point located on an inner contour line of a heart valve leaflet in each target plane; determining at least one first pushing reach point corresponding to the at least one first initial pushing point; determining at least one first pushing range of each target plane based on the at least one first pushing reach point; determining a second pushing range of the heart valve based on the at least one first pushing range; and determining an artificial heart valve that matches the heart valve based on the second pushing range.

Abstract: A display panel, a method for manufacturing same, and a display device. The display panel comprises a first substrate and a second substrate, the first substrate comprises a first base substrate, a black matrix and a spacer, the second substrate comprises a second base substrate and a conductive layer, and the spacer comprises a display area spacer and a peripheral area spacer. The peripheral area comprises a first region and a second region, the number of conductive layers in the first region is less than the number of conductive layers in the second region, and the peripheral area spacer comprises a plurality of first peripheral area spacers provided in the first region. An insulating island is provided between the first peripheral area spacer and the black matrix, and a pattern of the insulating island comprises island patterns arranged at intervals to be isolated from each other.

Abstract: Disclosed are an irradiation terminal based on a combination of rotating beam lines and an application thereof, the irradiation terminal comprises a combination of rotating beam lines, a rotating gantry, and an operation room. The combination of rotating beam lines includes a rotator beam line, a horizontal beam line, and an inclined beam line at a certain angle to the ground, and can achieve irradiation at different angles; the combination of rotating beam lines is arranged on the rotating gantry, and beam allocation for a plurality of operation rooms at different azimuth angles can be implemented through rotating a single combination of beam lines by 0-360 degrees by the rotating gantry; a plurality of rotating beam lines can be combined to achieve multi-angle beam irradiation in a single operation room.

Abstract: A tire tread detection device includes a main body. The main body is provided with a cavity, and a first opening and a second opening that are spaced along a first direction and are in communication with the cavity. The cavity is provided therein with a first camera module and a laser module, the first camera module is configured to capture a tire tread area of a tire to be measured through the first opening to obtain a tire tread image, and a laser line of the laser module passes through the second opening to reach the tire tread area of the tire to be measured to obtain depth data of the tire tread; a control assembly processes the obtained tire tread depth and image information of the tire tread and compares them with the original data to determine the wearing degree of the tire tread.

Abstract: A method for selecting an application and associated operational guidance to utilize on a mobile device is disclosed. In one embodiment, such a method identifies a selected environment of interest. Within the selected environment, the method identifies one or more applications that are commonly utilized by users within the selected environment and documents the one or more applications. The method detects physical entry of a particular user into the selected environment and, in response to detecting the entry, automatically notifies the particular user of the one or more applications that are commonly utilized within the selected environment. In certain embodiments, the method enables the user to quickly launch the one or more applications and/or provides operational guidance to the user with regard to using the one or more applications. A corresponding system and computer program product are also disclosed.

Abstract: A vehicle ADAS calibration device, including: a support platform; a lifting mechanism, foldable on the support platform, the lifting mechanism being hinged to the support platform; and an foldable arm mechanism, foldable on the lifting mechanism. The foldable arm mechanism is mounted on the lifting mechanism. By folding the foldable arm mechanism onto the lifting mechanism, the width of the vehicle ADAS calibration device can be reduced; and by folding the lifting mechanism onto the support platform, the height of the vehicle ADAS calibration device can be reduced, thereby facilitating storage and transportation.

Abstract: Disclosed is an intelligent monitoring method for soil moisture status based on remote sensing technology, including the following steps: dividing a monitoring region into a plurality of sub-regions by a processing end, acquiring image data of various sub-regions on the basis of remote sensing satellites, acquiring multi-source data related to soil moisture status of the monitoring region on the basis of sensor devices, and pre-processing the image data and the multi-source data; comprehensively analyzing the image data and the multi-source data, and assessing soil moisture status of the various sub-regions; and comprehensively analyzing overall soil moisture status of the monitoring region according to the soil moisture status of the various sub-regions. The soil moisture status of the monitoring region is assessed after the multi-source data is comprehensively analyzed by the monitoring method, bringing about a more comprehensive and accurate analysis.

Abstract: A method and system for controlling a device includes training a low-level policy to form a trained low-level policy and a low-level value function to form a trained goal conditioned value function, wherein training is performed using a static data set using goal conditioned episodes, training a high-level goal planner having high level goals having high-level sub-goals corresponding to a plurality of future time steps using the low-level value function to maximize a cumulative reward over the sub-goals for the plurality of future time steps so that the sub-goals are reachable by the low-level policy, obtaining an observation of a device, and generating an executable action using the low-level policy and the high-level goal planner and operating the device with the executable action.

Abstract: A compound represented by formula (I) is effective in inhibiting the growth of Clostridium difficile. Compared with nitazoxanide and other antibiotics, the compound also has significantly less influence on intestinal probiotics and lower toxic side effects while significantly inhibiting the activity of Clostridium difficile, and the disease is not easy to relapse after the drug is stopped.

Abstract: A compound as a receptor-interacting protein (RIP) inhibitor, a preparation method therefor, and a use thereof, which relate to the field of chemical medicines, are provided. The compound is a compound as represented by formula (I), or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a prodrug thereof. The compound has good inhibitory activity on humanized RIP1 kinase, and can be used for preparing drugs for resisting inflammation, resisting tumors and the like.

Abstract: An integrated equipment and treatment method for synchronous ecological treatment of domestic sewage and sludge, the equipment includes a one-piece box-shaped main body divided into several tank compartments which includes an anaerobic tank, a sludge reduction and denitrification tank, an aerobic tank, a sedimentation tank, and a disinfection tank, an inlet pipe for sewage and sludge entrance and an outlet pipe for exit of effluent after treatment. The sludge reduction and denitrification tank is equipped with variable microporous aeration pipes, worm fillers and multi-functional water quality online detectors. The aerobic tank is equipped with aeration pipeline components and DO online detectors. The sewage and sludge are guided to passing through the different tank compartments in order for simultaneous sewage treatment and sludge reduction. The removal rate of total nitrogen is as high as 85%, and the simultaneous reduction effect of sludge can reach more than 60%.

Abstract: Systems, methods, and computer-readable media are disclosed for estimating impressions for a digital out of home (DOOH) advertising spaces (e.g., digital billboards and screens). A DOOH advertising system may determine the location of relevant DOOH advertising spaces and the location of certain consumers with known attributes and a known location. Based on this information the DOOH advertising system may estimate a number of impressions for a given DOOH advertising space and a given consumer segment associated with attributes of consumers within a certain distance from the DOOH advertising space. Using this information, the DOOH advertising spaces having the highest estimated impressions for a given consumer segment may be identified.

Abstract: The present invention provides a device, kit and method for extracting and testing nucleic acids. The devices comprises: a first container (101), a second container (102), and an air storage device (103), wherein the first container (101) is used for accommodating or containing a reagent for extracting nucleic acids; a first valve (107) is provided between the first container (101) and the second container (102); the second container (102) and the gas storage device (103) are in fluid communication; the second container (102) has a sample inlet (104) and a sample outlet (105), and the sample inlet (104) is provided with a fourth valve (109); the sample outlet device, a waste liquid pool, a collecting pool and the like.

Abstract: The present invention relates to a reagent container and an operation method therefor, and a reagent treatment system.

Abstract: Systems and methods for pessimistic offline reinforcement learning are described herein. In one example, a method for performing offline reinforcement learning determines when sampled states are out of distribution, assigns high probability weights to the sampled states that are out of distribution, generates a fitted Q-function by solving an optimization problem with a minimization term and a maximization term, estimates a Q-value using the fitted Q-function by estimating the overall expected reward assuming the agent is in the present state and performs a present action, and updates the policy according to an existing reinforcement learning algorithm. The minimization term penalizes an overall expected reward when a present state is out of distribution. The maximization term cancels the minimization term when the present state is an in-distribution state.

Abstract: A compound as represented by formula I-1, or a pharmaceutically acceptable salt, a stereoisomer, or a solvate thereof are effective in reducing ALT, AST and ALP as well as helpful in treating hepatic pathological injuries (e.g. hepatocyte steatosis). The compound has wide application prospects in the preparation of a drug for preventing and/or treating liver diseases such as fatty liver, hepatic fibrosis and liver cirrhosis.

Abstract: The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

Abstract: An integrated equipment and treatment method for synchronous ecological treatment of domestic sewage and sludge, the equipment includes a one-piece box-shaped main body divided into several tank compartments which includes an anaerobic tank, a sludge reduction and denitrification tank, an aerobic tank, a sedimentation tank, and a disinfection tank, an inlet pipe for sewage and sludge entrance and an outlet pipe for exit of effluent after treatment. The sludge reduction and denitrification tank is equipped with variable microporous aeration pipes, worm fillers and multi-functional water quality online detectors. The aerobic tank is equipped with aeration pipeline components and DO online detectors. The sewage and sludge are guided to passing through the different tank compartments in order for simultaneous sewage treatment and sludge reduction. The removal rate of total nitrogen is as high as 85%, and the simultaneous reduction effect of sludge can reach more than 60%.