Abstract: Bifunctional compounds, which find utility as modulators of non-receptor Leucine-rich repeat kinase 2 (LRRK2), are described herein. In particular, the bifunctional compounds of the present disclosure contain on one end a moiety that binds to the cereblon E3 ubiquitin ligase and on the other end a moiety which binds LRRK2, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The bifunctional compounds of the present disclosure exhibit a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aberrant regulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: A method for colour component prediction, an encoder, a decoder and a storage medium are provided. The method includes that: prediction parameters of a current block are determined, the prediction parameters including a prediction mode parameter and a size parameter of the current block; when the prediction mode parameter indicates that a Matrix-based Intra Prediction (MIP) mode is adopted to determine an intra prediction value of the current block, an MIP weight matrix of the current block, a shift factor of the current block and an MIP input sample matrix of the current block are determined; and the intra prediction value of the current block is determined according to the MIP weight matrix, the shift factor and the MIP input sample matrix.

Abstract: A display panel and a display device are provided. The display panel includes a first display area and a second display area, wherein the display panel includes: a base substrate; a plurality of first repeating units arranged on the base substrate in an array and located in the first display area, each of the first repeating units including at least a first sub-pixel; a plurality of second repeating units arranged on the base substrate in an array and located in the second display area, each of the second repeating units including at least a second sub-pixel, wherein a color of light emitted by the first sub-pixel is the same as a color of light emitted by the second sub-pixel; a pixel defining layer disposed on the base substrate and located in both the first display area and the second display area, wherein the pixel defining layer includes a first opening located in the first display area and a second opening located in the second display area.

Abstract: Bifunctional compounds, which find utility as modulators of leucine-rich repeat kinase 2 (LRRK2), are described herein. In particular, the hetero-bifunctional compounds of the present disclosure contain on one end a moiety that binds to the cereblon E3 ubiquitin ligase and on the other end a moiety which binds LRRK2, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The hetero-bifunctional compounds of the present disclosure exhibit a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aberrant regulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: Provided in implementations of the present application are a filtering method and apparatus, and a computer storage medium; the method comprises: acquiring pixel information to be filtered; determining edge information; and inputting the sample information to be filtered and the edge information into a neural network-based filter so as to output filtered pixels, the filter being obtained by an online filtering part combined with an offline filtering part.

Abstract: A display substrate and a method manufacturing the same, an electronic apparatus are provided. The display substrate includes a display area including a first display region and a second display region, the first display region having a pixel density higher than that of the second display region, the display area including a base substrate, and a first electrode layer, a light-emitting functional layer, and a second electrode layer sequentially provided on the base substrate, the second electrode layer being on a side of the light-emitting functional layer away from the base substrate,. The second electrode layer includes a first electrode portion provided in the first display region and a second electrode portion provided in the second display region, the first electrode portion and the second electrode portion are electrically connected with each other, and the second electrode portion has a light transmittance higher than that of the first electrode portion.

Abstract: Disclosed are a display substrate and a method for manufacturing same, and a display apparatus.

Abstract: A pixel electrode (30), a pixel structure (001) comprising the pixel electrode (30), a display panel (00) and a display device, relating to the field of display technology. The pixel electrode (30) comprises a strip-shaped first electrode (301) and a plurality of strip-shaped second electrodes (302), each of the second electrodes (302) being connected to the first electrode (301), and the plurality of second electrodes (302) being arranged along an extending direction of the first electrode (301). Compared with the second electrodes (302), the first electrode (301) has a longer length and a wider width. As the width of the first electrode (301) is relatively wide, even if the length thereof is relatively long, the first electrode (301) is not prone to fracture.

Abstract: Provided is a system for analyzing features associated with entities using an embedding tree, the system including at least one processor programmed or configured to receive a dataset associated with a plurality of entities, wherein the dataset comprises a plurality of data instances for a plurality of entities. The processor may be programmed or configured to generate at least two embeddings based on the dataset and determine split criteria for partitioning an embedding space of at least one embedding tree associated with the dataset based on feature data associated with an entity and embedding data associated with the at least two embeddings. The processor may be programmed or configured to generate at least one embedding tree having a plurality of nodes based on the split criteria. Methods and computer program products are also provided.

Abstract: Embodiments of the present invention relate to the field of circuit technology, and disclose a method for correcting a SOC of a battery pack, a battery management system, and a vehicle. The method for correcting an SOC of a battery includes: determining, when a charging process of the battery pack starts, whether an initial SOC value of the battery pack is less than or equal to a preset electricity quantity threshold; when the initial SOC value of the battery pack is less than or equal to the preset electricity quantity threshold, recording state information of the battery pack during the charging process, and generating a differential capacity curve of the battery pack according to the state information; correcting a current SOC value of the battery pack according to the differential capacity curve and a voltage-SOC reference curve of a non-decay zone of the battery pack.

Abstract: The resource allocation method and apparatus are based on edge computing. The method includes: decomposing all application systems in a server into a plurality of meta-service units according to the coupling degree between different service modules in the application systems, and obtaining the quality of experience (QoE) index parameter value of each meta-service unit; clustering the plurality of meta-service units by using a clustering algorithm based on the QoE index parameter value of each meta-service unit; and allocating resources to each cluster according to the QoE index parameter values of all meta-service units in each cluster, so that all meta-service units in each cluster share the allocated resources. According to the invention, the resource allocation is more reasonable, the QoE value of a user is increased, and the resource use is more effective.

Abstract: A method, device, and apparatus for synthesizing a motion sequence of a virtual object and a non-transitory computer-readable storage medium are disclosed. The method can include obtaining description information of a motion sequence of a virtual object, and determining a continuous motion clip set similar to at least some motions in the motion sequence based on the description information and a continuous motion clip library constructed with video materials. The method can further include synthesizing the motion sequence of the virtual object based on the continuous motion clip set, where each continuous motion clip in the continuous motion clip library includes a unique identifier of the continuous motion clip, motion information of the continuous motion clip, and a representation vector corresponding to the each continuous motion clip.

Abstract: Provided is a method for implementing reinforcement learning by a neural network. The method may include performing, for each epoch of a first predetermined number of epochs, a second predetermined number of training iterations and a third predetermined number of testing iterations using a first neural network. The first neural network may include a first set of parameters, the training iterations may include a first set of hyperparameters, and the testing iterations may include a second set of hyperparameters. The testing iterations may be divided into segments, and each segment may include a fourth predetermined number of testing iterations. A first pattern may be determined based on at least one of the segments. At least one of the first set of hyperparameters or the second set of hyperparameters may be adjusted based on the pattern. A system and computer program product are also disclosed.

Abstract: The present disclosure discloses a dish washer. The dish washer includes a container, a spraying duct, and a water supply system. The container has a cleaning area therein. A plurality of spraying devices are provided, and each spraying device is provided with a spraying hole and has a water inflow end. The water supply system is in communication with a water supply and the water inflow end of the spraying device. According to the dish washer of the present disclosure, water spray can be individually controlled by the multiple water supply systems or by cooperation between one water supply system and the diverter valve. Thus, the dish washer has satisfactory water usage efficiency.

Abstract: A server device which is self-adaptive to different placements and locations includes a chassis, a plurality of storage elements, and a storage cabinet. First and third slide rails are positioned at opposite sides of the storage cabinet along a first direction. Second and fourth slide rails are positioned at other two opposing sides of the storage cabinet. The storage cabinet is movably positioned in the chassis along a third direction. When the chassis is horizontal, the first slide rail and the third slide rail provide support for the storage cabinet and when the chassis is vertical, support is provided by the second and fourth slide rails. The problem of the storage cabinet being difficult to slide when the placement of the chassis is changed is reduced, and the server device is more flexible in its placement.

Abstract: Embodiments of a method are disclosed. The method includes performing distributed deep learning training on multiple batches of training data using corresponding learners. Additionally, the method includes determining training times wherein the learners perform the distributed deep learning training on the batches of training data. The method also includes modifying a processing aspect of the straggler to reduce a future training time of the straggler for performing the distributed deep learning training on a new batch of training data in response to identifying a straggler of the learners by a centralized control.

Abstract: A user equipment (UE) monitors a Physical Downlink Control Channel (PDCCH) in multiple component carriers (CC). The UE determines if the UE is operating in carrier aggregation (CA) mode having a first CC in a first frequency band and a second CC in a second frequency band. When the UE is operating in CA with a first CC in the first frequency band and the second CC in the second frequency band, the UE determines a span pattern for PDCCH symbols being received on the first and second CC and selects a PDCCH monitoring type based on, at least, the span pattern. A UE also determines if a first CC and a second CC of a CA combination are collocated and selects a PDCCH monitoring type based on, at least, the determination of whether the first and second CC are collocated.

Abstract: The present invention belongs to the technical field of liquid crystal materials, and in particular relates to a negative liquid crystal composition and a liquid crystal display element or liquid crystal display containing the liquid crystal composition. The present invention discloses a negative dielectric nematic liquid crystal composition, comprising a compound represented by Formula I, one or more compounds represented by Formula II, and one or more compounds represented by Formula III. The liquid crystal composition has a relatively low rotational viscosity (?1), a high clearing point (Cp), a good solubility and a high stability to heat and light (VHR) on the basis of maintaining an appropriate optical anisotropy (?n), and can be used for developing a liquid crystal display element or liquid crystal display with a low cell thickness, a wide temperature for display, and a fast response.

Abstract: An electric machine with a low profile retention assembly for retention of a stator core is disclosed. A first housing houses the stator core. The first housing has an axial end face with a circumferentially extending, shaped profile having recessed portions that project axially inward alternating with non-recessed portions. A portion of the stator core extends axially out from the recessed portions. A core retention spring is disposed circumferentially at the axial end face of the first housing. The core retention spring has direct contact with the portion of the stator core that extends axially out from the recessed portions of the first housing and the shaped profile of the housing. The core retention spring pushes against the portion of the stator core that extends that extends axially out from the first housing, imparting one or more of an axial load and radial load into the stator core.

Abstract: The present technology provides for facilitating efficient identification of relevant metrics. In one embodiment, a set of candidate metrics for which to determine relevance to a user is identified. For each candidate metric, a set of distribution parameters is determined, including a first distribution parameter based on implicit positive feedback associated with the metric and usage data associated with the metric and a second distribution parameter based on the usage data associated with the metric. Such usage data can efficiently facilitate identifying relevance even with an absence of negative feedback. Using the set of distribution parameters, a corresponding distribution is generated. Each distribution can then be sampled to identify a relevance score for each candidate metric indicating an extent of relevance of the corresponding metric. Based on the relevance scores for each candidate metric, a candidate metric is designated as relevant to the user.