Patents by Inventor Weibo Chen

Weibo Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190345156
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bc1-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Application
    Filed: January 5, 2018
    Publication date: November 14, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Zuwen ZHOU, Chengxi HE, Zhifu LI, Yue RONG, Rui TAN, Huajie ZHANG, Hongbin LIU, Weipeng ZHANG, Haohan TAN, Zhifang CHEN, Lihua JIANG, Yanxin LIU, Min LIN, Jing SUN, Weibo WANG
  • Patent number: 10450316
    Abstract: Provided are certain CDK4/6 inhibitors with the structure of formula (I), pharmaceutical compositions thereof, and methods of use therefor. The compounds are of the class of pyrimidin-2 amine derivatives, useful for the treatment of hyper-proliferative diseases.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 22, 2019
    Assignees: CHONGQING FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Tongshuang Li, Haohan Tan, Zhifang Chen, Ling Chen, Qihong Liu, Yue Rong, Lijun Yang, Xianlong Wang, Rui Tan, Zuwen Zhou, Bin Liu, Min Lin, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • Publication number: 20190292962
    Abstract: An integrated device comprises a pump assembly and a nozzle assembly. The pump assembly has an accommodation compartment for accommodating the nozzle assembly, a pump assembly housing, and a pump. The pump assembly housing has an inlet passage and an outlet passage. The outlet passage is in communication with the nozzle assembly. The pump assembly comprises an enclosure; a motor coil for driving the pump; a magnetic body; a first gear assembly; and a second gear assembly. The first gear assembly and the second gear assembly mesh with each other. The nozzle assembly comprises a nozzle assembly housing, nozzle and a nozzle coil for driving the nozzle. The integrated device includes a pressure sensor that does not have an independent housing. The enclosure serves as a housing of the pressure sensor. The integrated device has a simple and compact structure, and facilitates realization of downsizing of the device. Also disclosed are an exhaust-gas aftertreatment system and a control method.
    Type: Application
    Filed: April 11, 2017
    Publication date: September 26, 2019
    Inventors: Xuelang WANG, Gaofeng FAN, Zhenqiu YANG, Weibo PENG, Hongwei SONG, Guoli CHEN
  • Publication number: 20190209566
    Abstract: Certain CDK4/6 inhibitors and pharmaceutically acceptable salts thereof are described. In particular, these compounds can inhibit kinase activity of CDK4/6 and may be useful for the treatment of hyper-proliferative diseases like cancer and inflammation. In addition, the pharmaceutical compositions thereof and methods of use thereof are also described.
    Type: Application
    Filed: May 5, 2017
    Publication date: July 11, 2019
    Inventors: Xingdong ZHAO, Tongshuang LI, Zhifang CHEN, Rui TAN, Ling CHEN, Xianlong WANG, Lijun YANG, Zuwen ZHOU, Yanxin LIU, Min LIN, Jing SUN, Weibo WANG
  • Patent number: 10328060
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: November 1, 2015
    Date of Patent: June 25, 2019
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES, CHONGQING FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Jian Ding, Linghua Meng, Meiyu Geng, Tongshuang Li, Zuwen Zhou, Ling Chen, Qihong Liu, Xianlong Wang, Lijun Yang, Yue Rong, Rui Tan, Chuiliang Yu, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • Publication number: 20190161489
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Application
    Filed: June 20, 2017
    Publication date: May 30, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Weipeng ZHANG, Zhifang CHEN, Ling CHEN, Xianlong WANG, Zhifu LI, Rui TAN, Lijun YANG, Haohan TAN, Bin LIU, Kai RAN, Zongyao ZOU, Min LIN, Jing SUN, Weibo WANG
  • Publication number: 20180372403
    Abstract: The present application provides a cooler for cooling a beverage fluid flow. The cooler may include a thermoelectric cooling device in communication with a fluid heat exchanger with the fluid flow therein and a water permeable membrane. The cooler further may include a fan positioned about the water permeable membrane for evaporative cooling therein.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 27, 2018
    Inventors: Jurgen ROEKENS, Gregg CARPENTER, Roberto Horn PEREIRA, Michael Gary IZENSON, Weibo CHEN, Scott David PHILLIPS, Christian Henry PASSOW
  • Publication number: 20170017273
    Abstract: Techniques for forming and adjusting a magnetic tension mechanism are described herein. A system includes a first magnetic element in a first component of a computing device. The system includes a second magnetic element in a second component of the computing device, wherein the first magnetic component and the second magnetic component are to be held in tension by a magnetic force. The system also includes an adjustment mechanism to adjust the force required to decouple the magnetic elements.
    Type: Application
    Filed: March 29, 2014
    Publication date: January 19, 2017
    Inventors: Kristin L. Weldon, Michael S. Brazel, Jered H. Wikander, Lily Kolle, Weibo Chen, Aleksander Magi, Konstantin I. Kouliachev, Ralph V. Miele, Richard P. Crawford
  • Publication number: 20140234123
    Abstract: The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed.
    Type: Application
    Filed: December 16, 2013
    Publication date: August 21, 2014
    Applicant: SustainX, Inc.
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick J. Magari, Benjamin Cameron, Robert Cook, Horst Richter
  • Patent number: 8763390
    Abstract: In various embodiments, compressed-gas energy storage and recovery systems include a cylinder assembly for compression and/or expansion of gas, a reservoir for storage and/or supply of compressed gas, and a system for thermally conditioning gas within the reservoir.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: July 1, 2014
    Assignee: SustainX, Inc.
    Inventors: Benjamin R. Bollinger, Troy O. McBride, Benjamin Cameron, Patrick Magari, Michael Izenson, Weibo Chen
  • Patent number: 8733094
    Abstract: The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: May 27, 2014
    Assignee: Sustainx, Inc.
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron, Robert Cook, Horst Richter
  • Patent number: 8627658
    Abstract: The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: January 14, 2014
    Assignee: SustainX, Inc.
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron, Robert Cook, Horst Richter
  • Publication number: 20120297776
    Abstract: In various embodiments, compressed-gas energy storage and recovery systems include a cylinder assembly for compression and/or expansion of gas, a reservoir for storage and/or supply of compressed gas, and a system for thermally conditioning gas within the reservoir.
    Type: Application
    Filed: August 1, 2012
    Publication date: November 29, 2012
    Inventors: Benjamin R. Bollinger, Troy O. McBride, Benjamin Cameron, Patrick Magari, Michael Izenson, Weibo Chen
  • Publication number: 20120299310
    Abstract: The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed.
    Type: Application
    Filed: June 25, 2012
    Publication date: November 29, 2012
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron, Robert Cook, Horst Richter
  • Patent number: 8250863
    Abstract: In various embodiments, compressed-gas energy storage and recovery systems include a cylinder assembly for compression and/or expansion of gas, a reservoir for storage and/or supply of compressed gas, and a system for thermally conditioning gas within the reservoir.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: August 28, 2012
    Assignee: SustainX, Inc.
    Inventors: Benjamin R. Bollinger, Troy O. McBride, Benjamin Cameron, Patrick Magari, Michael Izenson, Weibo Chen
  • Patent number: 8234862
    Abstract: The invention relates to systems and methods including an energy conversion system for storage and recovery of energy using compressed gas, a source of recovered thermal energy, and a heat-exchange subsystem in fluid communication with the energy conversion system and the source of recovered thermal energy.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: August 7, 2012
    Assignee: SustainX, Inc.
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron
  • Patent number: 8225606
    Abstract: The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: July 24, 2012
    Assignee: SustainX, Inc.
    Inventors: Troy O. McBride, Benjamin R. Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron, Robert Cook, Horst Richter
  • Patent number: 8122718
    Abstract: The invention relates to systems and methods including an energy conversion system for storage and recovery of energy using compressed gas, a source of recovered thermal energy, and a heat-exchange subsystem in fluid communication with the energy conversion system and the source of recovered thermal energy.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: February 28, 2012
    Assignee: SustainX, Inc.
    Inventors: Troy O. McBride, Benjamin Bollinger, Michael Izenson, Weibo Chen, Patrick Magari, Benjamin Cameron
  • Publication number: 20110283690
    Abstract: In various embodiments, compressed-gas energy storage and recovery systems include a cylinder assembly for compression and/or expansion of gas, a reservoir for storage and/or supply of compressed gas, and a system for thermally conditioning gas within the reservoir.
    Type: Application
    Filed: April 27, 2011
    Publication date: November 24, 2011
    Inventors: Benjamin R. Bollinger, Troy O. McBride, Benjamin Cameron, Patrick Magari, Michael Izenson, Weibo Chen
  • Patent number: 8061241
    Abstract: A cutting tool having a cutting element such as an insert is cooled indirectly by a micro-channel heat exchanger that is mounted against the rear face of the insert. The heat exchanger is formed with an internal cavity that receives a coolant such as a cryogen. The cavity may include fins to enhance the removal of heat by the cryogen from the insert. Coolant inlet and outlet tubes are coupled to the interior of the heat exchanger to supply cryogen to the cavity. The flow rate of cryogen required to cool the insert during a given machining operation is less than one percent of the amount of standard coolant required to cool the same insert during the same machining operation.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: November 22, 2011
    Assignee: Creare Incorporated
    Inventors: Jay Christopher Rozzi, Weibo Chen, Everett Edgar Archibald, Jr.