Abstract: The present invention relates to an organic compound, an organic electroluminescent material, and an organic electroluminescent element. The structural formula of the compound is shown in formula (I). When the organic compound of the present invention is used for preparing an organic electroluminescent element, the electron mobility, thermal stability, and luminescent characteristics are excellent; and the organic compound can be applied to an organic layer of the organic electroluminescent element. The organic compound of the present invention has a relatively good film-forming property; and when same is applied to an electron transport layer and an electron transport auxiliary layer, an organic electroluminescent element, which has a lower driving voltage, a higher light emission efficiency, and a longer service life than existing electron transport materials, can be manufactured, and thus, a full-color display panel with having improved performance and a prolonged service life can be manufactured.

Abstract: A computer-implemented method is provided for generating device parameters of circuits using a pretrained reinforcement learning (RL) agent composed of a graph neural network (GNN) and a fully connected neural network (FCNN). The method is performed by steps including acquiring inputs with respect to a set of desired specifications or one desired specification of a circuit, device parameters, a fixed topology of the circuit and providing the inputs to the RL agent. The desired circuit description includes a graph modeling the topology of the circuit and device parameters of the circuit, and the desired specifications include gain, bandwidth, phase margin, power consumption, output power and power efficiency.

Abstract: An integrated circuit is disclosed. The integrated circuit includes a first resonator, a second resonator, and a coupling element. The first resonator has a first terminal and a second terminal, where the first resonator comprises a gain resistor, a gain capacitor, and a gain inductor in parallel and electrically coupling the first terminal with the second terminal. The second resonator has a third terminal and a fourth terminal, where the second resonator includes a loss resistor, a loss capacitor, and a loss inductor in parallel and electrically coupling the third terminal with the fourth terminal. The coupling element selectively couples the first terminal of the first resonator with the third terminal of the second resonator.

Abstract: A self-priming starting device for a centrifugal pump is mounted on a water inlet pipe of the centrifugal pump and includes an outer housing, an inner housing, a primary spacer, a secondary spacer, an opening and closing disc and a tertiary spacer which are sequentially provided in the outer housing from top to bottom, and an elastic steel plate provided in the water inlet pipe. A drum is provided in the inner housing, and air inlet pipes and air discharging pipes are provided on the inner housing. The drum is provided with drum chambers and a three-blade support is provided in the drum. The opening and closing disc is provided with a vertical rod. A gas-liquid cutter is provided between the primary spacer and the secondary spacer. The primary spacer, the secondary spacer, the opening and closing disc and the tertiary spacer are provided with through-holes.

Abstract: The present invention relates to a method for concentrating a biological sample containing nucleic acids by using magnetic chitosan microparticles and subsequently performing a PCR reaction on the nucleic acids captured on the microparticles. The chitosan microparticles added to the biological sample at a PCR compatible pH are mechanically agitated to provide for cell lysis and simultaneous DNA capture, and then serve as a solid support for the nucleic acid template during the PCR reaction. As the chitosan microparticles are utilized for lysis and the nucleic acids do not need to be removed from the microparticles before PCR, the ease of the sample preparation procedure is dramatically improved.

Abstract: A self-priming starting device for a centrifugal pump is mounted on a water inlet pipe of the centrifugal pump and includes an outer housing, an inner housing, a primary spacer, a secondary spacer, an opening and closing disc and a tertiary spacer which are sequentially provided in the outer housing from top to bottom, and an elastic steel plate provided in the water inlet pipe. A drum is provided in the inner housing, and air inlet pipes and air discharging pipes are provided on the inner housing. The drum is provided with drum chambers and a three-blade support is provided in the drum. The opening and closing disc is provided with a vertical rod. A gas-liquid cutter is provided between the primary spacer and the secondary spacer. The primary spacer, the secondary spacer, the opening and closing disc and the tertiary spacer are provided with through-holes.

Abstract: The present invention relates to a method for concentrating a biological sample containing nucleic acids by using magnetic chitosan microparticles and subsequently performing a PCR reaction on the nucleic acids captured on the microparticles. The chitosan microparticles added to the biological sample at a PCR compatible pH are mechanically agitated to provide for cell lysis and simultaneous DNA capture, and then serve as a solid support for the nucleic acid template during the PCR reaction. As the chitosan microparticles are utilized for lysis and the nucleic acids do not need to be removed from the microparticles before PCR, the ease of the sample preparation procedure is dramatically improved.

Abstract: A photonic thermocycling device is configured to thermocycle a biological sample. The thermocycling device comprises a light source configured to emit an illumination beam, a reaction block holding a reaction chamber, and a light-absorbing film is coupled to the reaction block and configured to absorb and convert the illumination beam into thermal energy to heat the reaction chamber. A controller generates instructions for operation of the thermocycling device. The thermocycling device may further comprise a temperature sensor to measure the temperature of the reaction chamber for calibration of the instructions. A convection cooling element may also be implemented to provide rapid cooling of the reaction chamber. A lens assembly may be implemented for directing and conditioning light generated by the light source towards the light-absorbing film. A second partial light-absorbing film may be included and coupled on an opposite side of the first light-absorbing film, to improve heating uniformity.

Abstract: The structure has a subgrade or slope to be monitored and strip-shaped smart geosynthetic material compound devices. The strip-shaped smart geosynthetic material compound devices are buried to run through a subgrade or slope predicted slip crack surface. Gaps between the strip-shaped smart geosynthetic material compound devices and borehole inner walls are filled so that the force environment of the strip-shaped smart geosynthetic material compound devices is close to the subgrade or slope internal environment. Each strip-shaped smart geosynthetic material compound device has a strip-shaped geogrid, lead, and heat shrinkable tube. The lead is arranged in a length direction of the geogrid, and the lead and geogrid are fixedly connected at an interval of a set distance, with each fixed point forming a measuring point. The geogrid is wrapped in the heat shrinkable tube, and a free end of the lead is drawn out of the heat shrinkable tube.

Abstract: The present invention relates to systems and methods for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g., a well-plate); a liquid handling system comprising at least one robotic pipettor for aspirating, mixing, and dispensing reagent mixtures to the microfluidic cartridge; systems for data storage, processing, and output; and a system controller to coordinate the various devices and functions.

Abstract: The structure has a subgrade or slope to be monitored and strip-shaped smart geosynthetic material compound devices. The strip-shaped smart geosynthetic material compound devices are buried to run through a subgrade or slope predicted slip crack surface. Gaps between the strip-shaped smart geosynthetic material compound devices and borehole inner walls are filled so that the force environment of the strip-shaped smart geosynthetic material compound devices is close to the subgrade or slope internal environment. Each strip-shaped smart geosynthetic material compound device has a strip-shaped geogrid, lead, and heat shrinkable tube. The lead is arranged in a length direction of the geogrid, and the lead and geogrid are fixedly connected at an interval of a set distance, with each fixed point forming a measuring point. The geogrid is wrapped in the heat shrinkable tube, and a free end of the lead is drawn out of the heat shrinkable tube.

Abstract: The present invention relates to methods and systems for temperature correction in thermal melt analysis. More specifically, embodiments of the invention relate to the correction of the melting temperature (Tm) observed for a sample nucleic acid due to the effect of the nucleic acid concentration.

Abstract: The present invention relates to methods and systems for microfluidic DNA sample preparation. More specifically, embodiments of the present invention relate to methods and systems for the isolation of DNA from patient samples on a microfluidic device and use of the DNA for downstream processing, such as performing amplification reactions and thermal melt analysis on the microfluidic device.

Abstract: The present invention relates to a method for concentrating a biological sample containing nucleic acids by using magnetic chitosan microparticles and subsequently performing a PCR reaction on the nucleic acids captured on the microparticles. The chitosan microparticles added to the biological sample at a PCR compatible pH are mechanically agitated to provide for cell lysis and simultaneous DNA capture, and then serve as a solid support for the nucleic acid template during the PCR reaction. As the chitosan microparticles are utilized for lysis and the nucleic acids do not need to be removed from the microparticles before PCR, the ease of the sample preparation procedure is dramatically improved.

Abstract: The present invention relates to systems and methods for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g., a well-plate); a liquid handling system comprising at least one robotic pipettor for aspirating, mixing, and dispensing reagent mixtures to the microfluidic cartridge; systems for data storage, processing, and output; and a system controller to coordinate the various devices and functions.

Abstract: The present invention relates to systems and methods for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g., a well-plate); a liquid handling system comprising at least one robotic pipettor for aspirating, mixing, and dispensing reagent mixtures to the microfluidic cartridge; systems for data storage, processing, and output; and a system controller to coordinate the various devices and functions.

Abstract: The present invention relates to a method for reducing cross-contamination in continuous amplification reactions in channels of microfluidic devices. More specifically, the present invention relates to the use of specific materials continuously flowing in the channels to reduce adsorption of MgCl2 and the concomitant adsorption of nucleic acid template to the channel surface, thereby reducing cross-contamination. This reduction of cross-contamination improves the efficiency and reproducibility of the amplification reaction, e.g., PCR.

Abstract: The present invention relates to methods and systems for microfluidic DNA sample preparation. More specifically, embodiments of the present invention relate to methods and systems for the isolation of DNA from patient samples on a microfluidic device and use of the DNA for downstream processing, such as performing amplification reactions and thermal melt analysis on the microfluidic device.