Patents by Inventor Weidong Lyu

Weidong Lyu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LONG ACTING BI-SPECIFIC T CELL ENGAGERS TARGETING CD3 AND CD47
    Publication number: 20230391867
    Abstract: Provided are bispecific molecules and, in particular, long acting bispecific T cell engagers targeting CD3 and CD47 with improved efficacy, toxic profile and therapeutic window, and methods of making and using such long acting bispecific binding molecules.
    Type: Application
    Filed: November 17, 2021
    Publication date: December 7, 2023
    Applicant: Shenzhen Enduring Biotech, Ltd.
    Inventors: Yu Wen, Shumin Liu, Weidong Lyu, Dechun Wu
  • BISPECIFIC T-CELL ENGAGER WITH CLEAVABLE CYTOKINES FOR TARGETED IMMUNOTHERAPY
    Publication number: 20220233711
    Abstract: A long acting modified T-cell engager bispecific antibody with cytokine caps that provides reduced toxicity and boosted anti-tumor activity is disclosed. Method of making the modified and cytokine capped Bi-specific T-cell engager antibody is also disclosed.
    Type: Application
    Filed: May 15, 2020
    Publication date: July 28, 2022
    Applicant: SHENZHEN ENDURING BIOTECH, LTD.
    Inventors: Shumin Liu, Dechun Wu, Yu Wen, Yang Lei, Weidong Lyu