Patents by Inventor Weidong Zhao
Weidong Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11771759Abstract: An immune enhancer comprising at least an interferon and a granulocyte-macrophage colony-stimulating factor, and an immunotherapeutic phar-maceutical composition comprising at least an antigen and the above-mentioned immune enhancers is disclosed. A preparation method of the immunotherapeutic pharmaceutical composition, the use of the immune enhancer and the immunotherapeutic pharmaceutical composition are also disclosed. The immune enhancer can be applied to disease and tumor treatments caused by viruses, bacteria, and other microorganisms.Type: GrantFiled: January 24, 2018Date of Patent: October 3, 2023Assignee: Fudan UniversityInventors: Bin Wang, Weidong Zhao, Gan Zhao, Yiwei Zhong
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Publication number: 20220175912Abstract: The present invention provides an immune enhancer comprising at least an interferon and a granulocyte-macrophage colony-stimulating factor, and an immunotherapeutic pharmaceutical composition comprising at least an antigen and the above-mentioned immune enhancers. The present invention further discloses a preparation method of the immunotherapeutic pharmaceutical composition, the use of the immune enhancer and the immunotherapeutic pharmaceutical composition. The immune enhancer can be applied to disease and tumor treatments caused by viruses, bacteria, and other microorganisms.Type: ApplicationFiled: January 24, 2018Publication date: June 9, 2022Inventors: Bin WANG, Weidong ZHAO, Gan ZHAO, Yiwei ZHONG
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Patent number: 11327711Abstract: Examples are disclosed herein that are related to providing extended functionalities on-demand to an audio-based wearable device. One example provides a wearable computing device including an acoustic receiver configured to receive speech inputs, a speaker configured to present audio outputs, a communications subsystem configured to connect to an external device, a logic subsystem configured to execute instructions, and a storage subsystem having instructions executable by the logic subsystem to execute a program, connect to the external device via a wireless communications protocol, conduct an audio-based interaction of the program via the speech inputs received at the acoustic receiver and the audio outputs provided by the speaker, upon reaching a screen-based interaction of the program, notify a user via the speaker to interact with the external device, and provide image data to the external device for presentation via a screen of the external device.Type: GrantFiled: December 5, 2014Date of Patent: May 10, 2022Assignee: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Gary Caldwell, Ruchi Bhargava
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Patent number: 11119014Abstract: A method and apparatus for the rapid and reliable preparation of a sample for use in testing for target analytes such as bacteria, viruses, toxins and pathogenic agents in various products. A sample for testing the target analyte is collected from various sources. The method for sample preparation provides for an express process for preparing collected samples for testing. The collected sample may be concentrated by centrifugation, filtration, or other means suitable for sample concentration, homogenized with the addition of a broth and enriched for specified period of time. Immunomagnetic separation of the sample occurs with receptor-coated magnetic microspheres in different test-specific formulations (singleplex or multiplex). An automatic testing system is disclosed which includes a biological testing cassette, in which testing of the sample occurs using liquid crystal diagnostic methodologies.Type: GrantFiled: June 4, 2018Date of Patent: September 14, 2021Assignee: Pathogen Systems, Inc.Inventors: Curtis Hubert Stumpf, Weidong Zhao
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Patent number: 10841494Abstract: Video image stabilization provides better performance on a generic platform for computing devices by evaluating available multimedia digital signal processing components, and selecting the available components to utilize according to a hierarchy structure for video stabilization performance for processing parts of the video stabilization. The video stabilization has improved motion vector estimation that employs refinement motion vector searching according to a pyramid block structure relationship starting from a downsampled resolution version of the video frames. The video stabilization also improves global motion transform estimation by performing a random sample consensus approach for processing the local motion vectors, and selection criteria for motion vector reliability. The video stabilization achieves the removal of hand shakiness smoothly by real-time one-pass or off-line two-pass temporal smoothing with error detection and correction.Type: GrantFiled: April 3, 2019Date of Patent: November 17, 2020Assignee: Microsoft Technology Licensing, LLCInventors: Yongjun Wu, Nikola Borisov, Weidong Zhao, Shyam Sadhwani, Naveen Thumpudi
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Publication number: 20200300737Abstract: A method and apparatus for the rapid and reliable preparation of a sample for use in testing for target analytes such as bacteria, viruses, toxins and pathogenic agents in various products. A sample for testing the target analyte is collected from various sources. The method for sample preparation provides for an express process for preparing collected samples for testing. The collected sample may be concentrated by centrifugation, filtration, or other means suitable for sample concentration, homogenized with the addition of a broth and enriched for specified period of time. Immunomagnetic separation of the sample occurs with receptor-coated magnetic microspheres in different test-specific formulations (singleplex or multiplex). An automatic testing system is disclosed which includes a biological testing cassette, in which testing of the sample occurs using liquid crystal diagnostic methodologies.Type: ApplicationFiled: May 21, 2020Publication date: September 24, 2020Applicant: Pathogen Systems, Inc. dba Crystal Diagnostics LtdInventors: Curtis Hubert Stumpf, Weidong Zhao
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Patent number: 10637784Abstract: Technologies are described for performing equation-based rate control using delay. For example, an observed network data rate and a network delay can be obtained for a network communication. A target network data rate can be calculated using the observed network data rate and the network delay. The target network data rate is calculated using an equation-based approach. For example, the equation-based rate control can set the target network data rate to a value that is directly proportional to the observed network data rate and inversely related to the network delay. The target network data rate is used to set the bitrate for the network communication.Type: GrantFiled: May 20, 2019Date of Patent: April 28, 2020Assignee: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Publication number: 20190297263Abstract: Video image stabilization provides better performance on a generic platform for computing devices by evaluating available multimedia digital signal processing components, and selecting the available components to utilize according to a hierarchy structure for video stabilization performance for processing parts of the video stabilization. The video stabilization has improved motion vector estimation that employs refinement motion vector searching according to a pyramid block structure relationship starting from a downsampled resolution version of the video frames. The video stabilization also improves global motion transform estimation by performing a random sample consensus approach for processing the local motion vectors, and selection criteria for motion vector reliability. The video stabilization achieves the removal of hand shakiness smoothly by real-time one-pass or off-line two-pass temporal smoothing with error detection and correction.Type: ApplicationFiled: April 3, 2019Publication date: September 26, 2019Applicant: Microsoft Technology Licensing, LLCInventors: Yongjun Wu, Nikola Borisov, Weidong Zhao, Shyam Sadhwani, Naveen Thumpudi
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Publication number: 20190273689Abstract: Technologies are described for performing equation-based rate control using delay. For example, an observed network data rate and a network delay can be obtained for a network communication. A target network data rate can be calculated using the observed network data rate and the network delay. The target network data rate is calculated using an equation-based approach. For example, the equation-based rate control can set the target network data rate to a value that is directly proportional to the observed network data rate and inversely related to the network delay. The target network data rate is used to set the bitrate for the network communication.Type: ApplicationFiled: May 20, 2019Publication date: September 5, 2019Applicant: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Patent number: 10341240Abstract: Technologies are described for performing equation-based rate control using delay. For example, an observed network data rate and a network delay can be obtained for a network communication. A target network data rate can be calculated using the observed network data rate and the network delay. The target network data rate is calculated using an equation-based approach. For example, the equation-based rate control can set the target network data rate to a value that is directly proportional to the observed network data rate and inversely related to the network delay. The target network data rate is used to set the bitrate for the network communication.Type: GrantFiled: December 12, 2016Date of Patent: July 2, 2019Assignee: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Patent number: 10257421Abstract: Video image stabilization provides better performance on a generic platform for computing devices by evaluating available multimedia digital signal processing components, and selecting the available components to utilize according to a hierarchy structure for video stabilization performance for processing parts of the video stabilization. The video stabilization has improved motion vector estimation that employs refinement motion vector searching according to a pyramid block structure relationship starting from a downsampled resolution version of the video frames. The video stabilization also improves global motion transform estimation by performing a random sample consensus approach for processing the local motion vectors, and selection criteria for motion vector reliability. The video stabilization achieves the removal of hand shakiness smoothly by real-time one-pass or off-line two-pass temporal smoothing with error detection and correction.Type: GrantFiled: December 14, 2016Date of Patent: April 9, 2019Assignee: Microsoft Technology Licensing, LLCInventors: Yongjun Wu, Nikola Borisov, Weidong Zhao, Shyam Sadhwani, Naveen Thumpudi
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Patent number: 10129155Abstract: Technologies are described for performing hybrid rate control that switches between a delay-based mode and a passive loss-based mode for a flow of network traffic. The switching can be performed based on the presence of loss-based TCP network flows. For example, rate control can be performed for a flow of network traffic in a delay-based mode. When the presence of a loss-based TCP network flow is detected, the flow of network traffic can be switched from the delay-based mode to a passive loss-based mode and rate control can be performed in the passive loss-based mode. When the loss-based TCP flow is no longer detected, the flow of network traffic can be switched back to the delay-based mode.Type: GrantFiled: November 21, 2016Date of Patent: November 13, 2018Assignee: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Patent number: 10127665Abstract: The present invention discloses an intelligent assistant judgment system for images of cervix uteri and a processing method thereof. This system comprises a colposcope device and an assistant judgment device. By combining the colposcope device and the assistant judgment device together to obtain the images of the cervix uteri to be detected by the colposcope device and to compare and analyze the images of the cervix uteri to be detected and its characteristic data by the assistant judgment device, the present invention can judge whether the current cervix uteri to be detected are normal cervix uteri, and can obtain, from the characteristic data of the images of the cervix uteri to be detected, the type of a lesion occurring in the current cervix uteri to be detected and characteristic parameters of the lesion. The doctors are assisted in making correct diagnosis and judgment.Type: GrantFiled: May 9, 2018Date of Patent: November 13, 2018Inventors: Shuai Ding, Shanlin Yang, Weidong Zhao, Jie Ma, Qiang Fu, Lin Zhang, Zeyuan Wang
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Publication number: 20180283997Abstract: A method and apparatus for the rapid and reliable preparation of a sample for use in testing for target analytes such as bacteria, viruses, toxins and pathogenic agents in various products. A sample for testing the target analyte is collected from various sources. The method for sample preparation provides for an express process for preparing collected samples for testing. The collected sample may be concentrated by centrifugation, filtration, or other means suitable for sample concentration, homogenized with the addition of a broth and enriched for specified period of time. Immunomagnetic separation of the sample occurs with receptor-coated magnetic microspheres in different test-specific formulations (singleplex or multiplex). An automatic testing system is disclosed which includes a biological testing cassette, in which testing of the sample occurs using liquid crystal diagnostic methodologies.Type: ApplicationFiled: June 4, 2018Publication date: October 4, 2018Applicant: Pathogen Systems, Inc. dba Crystal Diagnostics LtdInventors: Curtis Hubert Stumpf, Weidong Zhao
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Publication number: 20180167328Abstract: Technologies are described for performing equation-based rate control using delay. For example, an observed network data rate and a network delay can be obtained for a network communication. A target network data rate can be calculated using the observed network data rate and the network delay. The target network data rate is calculated using an equation-based approach. For example, the equation-based rate control can set the target network data rate to a value that is directly proportional to the observed network data rate and inversely related to the network delay. The target network data rate is used to set the bitrate for the network communication.Type: ApplicationFiled: December 12, 2016Publication date: June 14, 2018Applicant: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Publication number: 20180145914Abstract: Technologies are described for performing hybrid rate control that switches between a delay-based mode and a passive loss-based mode for a flow of network traffic. The switching can be performed based on the presence of loss-based TCP network flows. For example, rate control can be performed for a flow of network traffic in a delay-based mode. When the presence of a loss-based TCP network flow is detected, the flow of network traffic can be switched from the delay-based mode to a passive loss-based mode and rate control can be performed in the passive loss-based mode. When the loss-based TCP flow is no longer detected, the flow of network traffic can be switched back to the delay-based mode.Type: ApplicationFiled: November 21, 2016Publication date: May 24, 2018Applicant: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Sanjeev Mehrotra, Jayashree Sadagopan, Costin Hagiu
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Publication number: 20180145780Abstract: Technologies are described for determining clock offsets between computing devices. Clock offsets between the computing devices are determined based on timestamp information associated with forward packets and reverse packets sent between the computing devices. For example, a forward series and a reverse series of timestamp points can be obtained from forward and reverse network packets. A forward anchor series and a reverse anchor series can be generated from the forward series and the reverse series. The clock offset between the computing devices can be estimated using the forward anchor series and the reverse anchor series.Type: ApplicationFiled: November 21, 2016Publication date: May 24, 2018Applicant: Microsoft Technology Licensing, LLCInventors: Weidong Zhao, Jayashree Sadagopan
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Patent number: 9965094Abstract: Touchscreen testing techniques are described. In one or more implementations, a piece of conductor (e.g., metal) is positioned as proximal to a touchscreen device and the touchscreen device is tested by simulating a touch of a user. This technique may be utilized to perform a variety of different testing of a touchscreen device, such as to test latency and probabilistic latency. Additional techniques are also described including contact geometry testing techniques.Type: GrantFiled: August 4, 2011Date of Patent: May 8, 2018Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Aleksandar Uzelac, David A. Stevens, Weidong Zhao, Takahiro Shigemitsu, Briggs A. Willoughby, John Graham Pierce, Pravin Kumar Santiago, Craig S. Ranta, Timothy Allen Wright, Jeffrey C. Maier, Robert T. Perry, Stanimir Naskov Kirilov
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Publication number: 20170331744Abstract: A computing system manages communications congestion by selecting a transmission rate differently in different operating modes. In a delay-plus-loss mode, the transmission rate is selected as the lesser of a rate that would be selected by loss-based algorithm or by a delay-based algorithm. In a loss-based mode, the transmission rate is selected as the lesser of a rate that would be selected by loss-based algorithm, on one hand, and the maximum of a rate that would be selected by a delay-based algorithm or a rate proportional to the maximum estimated link rate divided by the number of data flows estimated to be competing for link bandwidth on the other hand. A database may be maintained of observations of network and link performance over time, where the database contains such information as the maximum estimated link rate capacity, minimum delays, and minimum losses.Type: ApplicationFiled: May 11, 2016Publication date: November 16, 2017Inventors: Sanjeev Mehrotra, Weidong Zhao, Alex Filenkov, Costin Hagiu
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Patent number: 9819970Abstract: Video decoding innovations for multithreading implementations and graphics processor unit (“GPU”) implementations are described. For example, for multithreaded decoding, a decoder uses innovations in the areas of layered data structures, picture extent discovery, a picture command queue, and/or task scheduling for multithreading. Or, for a GPU implementation, a decoder uses innovations in the areas of inverse transforms, inverse quantization, fractional interpolation, intra prediction using waves, loop filtering using waves, memory usage and/or performance-adaptive loop filtering. Innovations are also described in the areas of error handling and recovery, determination of neighbor availability for operations such as context modeling and intra prediction, CABAC decoding, computation of collocated information for direct mode macroblocks in B slices, reduction of memory consumption, implementation of trick play modes, and picture dropping for quality adjustment.Type: GrantFiled: December 9, 2013Date of Patent: November 14, 2017Assignee: Microsoft Technology Licensing, LLCInventors: Yegnaswamy Sermadevi, Weidong Zhao, Eric S. Christoffersen, Yongjun Wu, Juan Carlos Arevalo Baeza, Sean Callahan