Patents by Inventor Weiguo Cui

Weiguo Cui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of manufacturing dual specific T-cells for use in cancer immunotherapy
    Patent number: 11965177
    Abstract: The present invention relates to autologous dual-specific lymphocytes, methods of making and uses for the treatment of tumors.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: April 23, 2024
    Assignee: VERSITI BLOOD RESEARCH FOUNDATION, INC.
    Inventor: Weiguo Cui
  • BCG CAR CONSTRUCTS AND METHODS OF THEIR MANUFACTURE AND USE
    Publication number: 20230036135
    Abstract: Provided herein are antibodies and antigen binding fragments thereof specific to BCG antigen Ag85B as well as chimeric antigen receptors and lymphocytes comprising Ag85B antibodies as described and methods of treating cancer and tuberculosis infections using the CAR lymphocytes described. In a first aspect, provided herein is an isolated antibody or antigen binding fragment thereof capable of binding Bacillus Calmette-Guerin (BCG) antigen Ag85B.
    Type: Application
    Filed: December 8, 2020
    Publication date: February 2, 2023
    Inventor: Weiguo Cui
  • Method of Manufacturing Dual Specific T-Cells for Use in Cancer Immunotherapy
    Publication number: 20210189338
    Abstract: The present invention relates to autologous dual-specific lymphocytes, methods of making and uses for the treatment of tumors.
    Type: Application
    Filed: January 28, 2021
    Publication date: June 24, 2021
    Inventor: Weiguo Cui
  • Method of manufacturing dual-specific T-cells for use in cancer immunotherapy
    Patent number: 10941381
    Abstract: The present invention relates to autologous dual-specific lymphocytes, methods of making and uses for the treatment of tumors. In particular, the invention relates to methods producing autologous dual-specific lymphocytes comprising an endogenous receptor for at least one tumor associated antigen and an exogenous receptor for a strong antigen.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: March 9, 2021
    Assignee: VERSITI BLOOD RESEARCH INSTITUTE FOUNDATION, INC.
    Inventor: Weiguo Cui
  • METHOD OF MANUFACTURING DUAL-SPECIFIC T-CELLS FOR USE IN CANCER IMMUNOTHERAPY
    Publication number: 20180334651
    Abstract: The present invention relates to autologous dual-specific lymphocytes, methods of making and uses for the treatment of tumors. In particular, the invention relates to methods producing autologous dual-specific lymphocytes comprising an endogenous receptor for at least one tumor associated antigen and an exogenous receptor for a strong antigen.
    Type: Application
    Filed: November 18, 2016
    Publication date: November 22, 2018
    Inventor: Weiguo Cui