Patents by Inventor Weihua Chang

Weihua Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230348973
    Abstract: The present disclosure is generally directed to strategies for template capture and amplification during sequencing. In some examples, a solid support is used for template capture and amplification.
    Type: Application
    Filed: March 30, 2023
    Publication date: November 2, 2023
    Inventors: Xiaoyu Ma, Mathieu Lessard-Viger, Eric Brustad, Jeffrey Fisher, Jonathan Boutell, Weihua Chang
  • Publication number: 20230279469
    Abstract: An example of a flow cell includes a substrate having depressions separated by interstitial regions. First and second primers are immobilized within the depressions. First transposome complexes are immobilized within the depressions, and the first transposome complexes include a first amplification domain. Second transposome complexes are also immobilized within the depressions, and the second transposome complexes include a second amplification domain. Some of the first transposome complexes, or some of the second transposome complexes, or some of both of the first and second transposome complexes include a modification to reduce tagmentation efficiency.
    Type: Application
    Filed: December 23, 2022
    Publication date: September 7, 2023
    Inventors: Johan Sebastian Basuki, Jonathan Mark Boutell, Jeffrey S. Fisher, Louise Jane Fraser, Wayne N. George, Niall Anthony Gormley, David Jones, Xiaoyu Ma, Maria Ines Martins Vitoriano, Zhong Mei, Oliver Jon Miller, Andrew Price, Sebastien Georg Gabriel Ricoult, Vicki S. Thomson, Jacqueline C. Weir, Xiaoy Ma, Weihua Chang, Hui Han
  • Publication number: 20230105642
    Abstract: Embodiments relate to the preparation of nucleic acid libraries. Some embodiments relate to the preparation of normalized nucleic acid libraries, such as libraries in which the amounts of amplified nucleic acids are substantially the same for different amounts of input nucleic acids. Some embodiments relate to preparation of indexed nucleic acid libraries with certain adaptors.
    Type: Application
    Filed: March 29, 2021
    Publication date: April 6, 2023
    Inventors: Lena Christiansen, Dmitry Pokholok, Frank J. Steemers, Rigo Pantoja, Megan Chu, Patrizia lavicoli, Weihua Chang, Jeffrey Dennis Brodin, Eric Vermaas, Jerishah Thomas, Fan Zhang
  • Publication number: 20050181394
    Abstract: This invention provides methods of amplifying genomic DNA to obtain an amplified representative population of genome fragments. Methods are further provided for obtaining amplified genomic DNA representations of a desired complexity. The invention further provides methods for simultaneously detecting large numbers of typable loci for an amplified representative population of genome fragments. Accordingly the methods can be used to genotype individuals on a genome-wide scale.
    Type: Application
    Filed: December 7, 2004
    Publication date: August 18, 2005
    Applicant: Illumina, Inc.
    Inventors: Frank Steemers, Weihua Chang, Min-Jui Shen, Kevin Gunderson