Patents by Inventor Weijie Lan

Weijie Lan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR ENHANCING ACTIVITY OF T CELLS WITH MODIFIED B CELLS
    Publication number: 20230137343
    Abstract: The present invention relates to methods and combination therapies for enhancing the activity and function of non-B cell immune cells (such as T cells) using genetically modified B cells. These methods and combinations can be used, for example, for the treatment of a variety of diseases and disorders, including cancer, heart disease, inflammatory disease, muscle wasting disease, neurological disease, and the like.
    Type: Application
    Filed: October 6, 2022
    Publication date: May 4, 2023
    Inventors: Kathleen BOYLE, Hangil PARK, Srinivas KOTHAKOTA, Mark SELBY, Thomas BRENNAN, Lewis T. WILLIAMS, Rosa Romano, Weijie Lan
  • Genomic engineering of pluripotent cells
    Patent number: 11352607
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: June 7, 2022
    Assignee: Fate Therapeutics, Inc.
    Inventors: Bahram Valamehr, Ramzey Abujarour, Tom Tong Lee, Weijie Lan, Raedun Clarke, Ryan Bjordahl
  • GENOMIC ENGINEERING OF PLURIPOTENT CELLS
    Publication number: 20210324340
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 21, 2021
    Inventors: Bahram VALAMEHR, Ramzey ABUJAROUR, Tom Tong LEE, Weijie LAN, Raedun CLARKE, Ryan BJORDAHL
  • Genomic engineering of pluripotent cells
    Patent number: 11072781
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: July 27, 2021
    Assignee: FATE THERAPEUTICS, INC.
    Inventors: Bahram Valamehr, Ramzey Abujarour, Tom Tong Lee, Weijie Lan, Raedun Clarke, Ryan Bjordahl
  • GENOMIC ENGINEERING OF PLURIPOTENT CELLS
    Publication number: 20200095604
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Application
    Filed: October 17, 2019
    Publication date: March 26, 2020
    Inventors: Bahram VALAMEHR, Ramzey ABUJAROUR, Tom Tong LEE, Weijie LAN, Raedun CLARKE, Ryan BJORDAHL
  • GENOMIC ENGINEERING OF PLURIPOTENT CELLS
    Publication number: 20190271005
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Application
    Filed: April 9, 2019
    Publication date: September 5, 2019
    Inventors: Bahram Valamehr, Ramzey Abujarour, Tom Tong Lee, Weijie Lan, Raedun Clarke, Ryan Bjordahl
  • Genomic engineering of pluripotent cells
    Patent number: 10287606
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: May 14, 2019
    Assignee: Fate Therapeutics, Inc.
    Inventors: Bahram Valamehr, Ramzey Abujarour, Tom Tong Lee, Weijie Lan, Raedun Clarke, Ryan Bjordahl
  • GENOMIC ENGINEERING OF PLURIPOTENT CELLS
    Publication number: 20180155717
    Abstract: Provided are methods and compositions for obtaining genome-engineered iPSCs, and derivative cells with stable and functional genome editing at selected sites. Also provided are cell populations or clonal cell lines derived from genome-engineered iPSCs, which comprise targeted integration of one or more exogenous polynucleotides, and/or in/dels in one or more selected endogenous genes.
    Type: Application
    Filed: November 20, 2017
    Publication date: June 7, 2018
    Inventors: Bahram Valamehr, Ramzey Abujarour, Tom Tong Lee, Weijie Lan, Raedun Clarke, Ryan Bjordahl