Abstract: Provided are a LAG-3 antibody, an antigen-binding fragment thereof, and a pharmaceutical application thereof. Further, provided are a chimeric antibody comprising a CDR of the LAG-3 antibody, a humanized antibody, a pharmaceutical composition comprising the LAG-3 antibody and the antigen-binding fragment thereof, and an application of the pharmaceutical composition as an antineoplastic drug. Particularly, provided is an application of a humanized LAG-3 antibody in preparation of drugs for treatment of diseases involving immune cells.

Abstract: Systems and methods for image correction are provided. The systems and methods may obtain raw data of a target object. The systems and methods may determine, based on the raw data of the target object, a target phase. The systems and methods may generate a first image corresponding to the target phase. The systems and methods may determine, using a preset evaluation tool, an image quality evaluation result of the first image. In response to determining that the image quality evaluation result of the first image does not satisfy a preset condition, the systems and methods may generate a set of corrected raw sub-data of the target object corresponding to the target phase by correcting a set of raw sub-data of the target object corresponding to the target phase. The systems and methods may generate, based on the set of corrected raw sub-data of the target object, a corrected image corresponding to the first image.

Abstract: A method for scaling the porcelain material of a restoration and the associated machining process is invented, which comprises: establishing a data model of the restoration (S100); dividing the bonding surface or interface between veneer porcelain to be prepared and a restoration substrate into a finite number of element surfaces (S200); establishing the direction coordinate axis on every element surface as its reference axis for setting up a size and a thickness value of veneer porcelain of each element surface (S300); determining and specifying the size and thickness of the veneer porcelain of every element surface according to the preset size and thickness value, and completing the bonding surface by covering it with the veneer porcelain composed of all the element surfaces as scaled with those sizes and thickness values as referred to (S400); generating the outer contour of the veneer porcelain of a clinic restoration (S500).