Patents by Inventor Weili Duan

Weili Duan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered monomeric antibody fragments
    Patent number: 10233229
    Abstract: The present invention relates to monomeric polypeptides comprising an engineered monomeric antibody fragment (e.g., monomeric Fc-containing polypeptides) wherein the monomeric Fc comprises one or more engineered N-linked glycosylation sites in the CH3-CH3 dimerization interface. Methods for producing such engineered monomeric antibody fragments and their use in diagnostics and therapeutics are also provided.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: March 19, 2019
    Assignee: Pfizer Inc.
    Inventors: Tetsuya Ishino, Weili Duan, Ronald William Kriz
  • ENGINEERED MONOMERIC ANTIBODY FRAGMENTS
    Publication number: 20150322135
    Abstract: The present invention relates to monomeric polypeptides comprising an engineered monomeric antibody fragment (e.g., monomeric Fc-containing polypeptides) wherein the monomeric Fc comprises one or more engineered N-linked glycosylation sites in the CH3-CH3 dimerization interface. Methods for producing such engineered monomeric antibody fragments and their use in diagnostics and therapeutics are also provided.
    Type: Application
    Filed: November 25, 2013
    Publication date: November 12, 2015
    Inventors: Tetsuya Ishino, Weili Duan, Ronald William Kriz