Abstract: The present application provides an application of Chidamide in combination with R-CHOP in preparing a drug used for treating B-cell lymphoma, and also provides a drug comprising Chidamide and R-CHOP. Chidamide in combination with R-CHOP has a synergistic therapeutic effect on B-cell lymphoma.

Abstract: A sealing quality detection device for gas extraction boreholes includes a detection host, a detection pipe, a sealing element, and a three-way pipe. A plurality of air inlets and a plurality of exhaust ports are formed above the detection host, a negative pressure injector is arranged in the detection host, a quick joint and a control switch are also arranged on the detection host, the quick joint is used to be connected with an underground wind pipe, the underground wind pipe is connected to an underground compressed air tube, and the control switch is used for starting and switching off the negative pressure injector in the detection host. A sealing quality evaluating method for gas extraction boreholes is provided.

Abstract: A sealing quality detection device for gas extraction boreholes includes a detection host, a detection pipe, a sealing element, and a three-way pipe. A plurality of air inlets and a plurality of exhaust ports are formed above the detection host, a negative pressure injector is arranged in the detection host, a quick joint and a control switch are also arranged on the detection host, the quick joint is used to be connected with an underground wind pipe, the underground wind pipe is connected to an underground compressed air tube, and the control switch is used for starting and switching off the negative pressure injector in the detection host. A sealing quality evaluating method for gas extraction boreholes is provided.

Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.

Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.

Abstract: The disclosure provides an outdoor device for simulating a pond ecosystem comprising a plurality of simulated ponds connected together by pipelines and including an adjusting pool, a plurality of control groups and a plurality of treatment groups with different concentrations; the plurality of control groups and the treatment groups are randomly distributed in the ponds according to a random draw method or a random allocation method, and the adjusting pool is a transfer station for water inlets and outlets of the ponds. According to the device, the plurality of control groups and treatment groups are arranged in a system, achieving a scale of a middle-scale pond ecological simulation system, which can stimulate an actual complex hydrostatic ecological system including a plurality of aquatic macrophytes, algae, zooplankton, benthos and microorganisms, and evaluate the effects of the complex ecological efficiency caused by chemical pollutants entering an actual water body.

Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.

Abstract: Provided are antibodies or fragments thereof having binding specificity to the human interferon alpha and beta receptor subunit 1 (IFNAR1) protein. In various examples, the antibodies or fragments thereof include a VH and VL CDRs as disclosed herein, or variants thereof. Methods of using the antibodies or fragments thereof for treating autoimmune diseases and disorders are also provided.

Abstract: The disclosure provides an outdoor device for simulating a pond ecosystem comprising a plurality of simulated ponds connected together by pipelines and including an adjusting pool, a plurality of control groups and a plurality of treatment groups with different concentrations; the plurality of control groups and the treatment groups are randomly distributed in the ponds according to a random draw method or a random allocation method, and the adjusting pool is a transfer station for water inlets and outlets of the ponds. According to the device, the plurality of control groups and treatment groups are arranged in a system, achieving a scale of a middle-scale pond ecological simulation system, which can stimulate an actual complex hydrostatic ecological system including a plurality of aquatic macrophytes, algae, zooplankton, benthos and microorganisms, and evaluate the effects of the complex ecological efficiency caused by chemical pollutants entering an actual water body.

Abstract: Provided are antibodies or fragments thereof having binding specificity to the human interferon alpha and beta receptor subunit 1 (IFNAR1) protein. In various examples, the antibodies or fragments thereof include a VH and VL CDRs as provided, or variants thereof. Methods of using the antibodies or fragments thereof for treating autoimmune diseases and disorders are also provided.

Abstract: Provided are antibodies or fragments thereof having binding specificity to the human interferon alpha and beta receptor subunit 1 (IFNAR1) protein. In various examples, the antibodies or fragments thereof include a VH and VL CDRs as provided, or variants thereof. Methods of using the antibodies or fragments thereof for treating autoimmune diseases and disorders are also provided.

Abstract: An apparatus for plasmatizing solid-fuel combustion additive and the method for using the same are provided. The apparatus is made from a reaction vessel, electrodes, a power supply, a carrier gas intake device, a feed device and an outlet of the plasmatization reaction vessel. The method to use this apparatus is as following: The additive is added into the reaction vessel through the feed device in which the carrier gas passes and carries the additive into the electrode region for evaporation and (partially) plasmatization; and the plasmatized gas from the outlet of the reactor is introduced into any combustion chamber. The additive is an organometallic compound or a mixture of the organometallic compounds, or their derivative, eutectic compound or coordination agent containing at least one organometallic compound.