Patents by Inventor Weilin Sun

Weilin Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210376775
    Abstract: Disclosed is a displacement correction apparatus. The apparatus comprises: a reference circuit and a correction circuit; the reference circuit is configured to provide a reference signal; the correction circuit is configured to perform a logarithm operation on a nonlinear displacement signal to be corrected based on the reference signal, to obtain a corrected linear displacement signal. The displacement correction apparatus can solve the problem of poor detection accuracy resulting from a position signal output by an eddy current sensor being not in a linear relationship with a displacement signal of a shaft, thereby achieving the effect of improving detection accuracy. A magnetic levitation bearing system and a displacement correction method therefor which use the above displacement correction apparatus are also disclosed.
    Type: Application
    Filed: August 12, 2021
    Publication date: December 2, 2021
    Inventors: Weilin GUO, Cong ZHAO, Yongling HE, Daofu HU, Xue LI, Jiandong SUN
  • Patent number: 11188694
    Abstract: The invention discloses a dynamic simulation method of circulating temperature variation in RMR subsea pump mud-lift drilling system, including steps: obtaining operating parameters, environmental parameters, well structure parameters and thermal parameters of target well; establishing temperature control equation of drill string in seawater section, temperature control equation of drill string in formation section, temperature control equation of annulus in formation section, and temperature control equation of return pipe in seawater section; re-determining initial and boundary conditions; discretizing spatial structure of the whole system with inner node method; discretizing control equations on corresponding nodes; substituting corresponding parameters into discrete expressions to obtain circulating temperature in drill string of seawater section, circulating temperature in drill string of formation section, circulating temperature in annulus of formation section, and circulating temperature in return pip
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: November 30, 2021
    Assignee: SOUTHWEST PETROLEUM UNIVERSITY
    Inventors: Xin Li, Jie Zhang, Cuinan Li, Peigang Wang, Xuefeng Sun, Xiaoxiao Du, Weilin Chen, Lin Chen
  • Publication number: 20200102312
    Abstract: The disclosure relates to novel selective Grp94 inhibitors, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as cancer, comprising administering to an animal in need thereof an effective amount of such compounds.
    Type: Application
    Filed: April 5, 2019
    Publication date: April 2, 2020
    Inventors: Gabriela Chiosis, Pengrong Yan, Pallav Patel, Hardik J. Patel, Tony Taldone, Chenghua Yang, Weilin Sun, Stefan O. Ochiana
  • Patent number: 10421758
    Abstract: The disclosure relates to novel selective Grp94 inhibitors, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as cancer, comprising administering to an animal in need thereof an effective amount of such compounds.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: September 24, 2019
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Gabriela Chiosis, Pengrong Yan, Pallav Patel, Hardik J. Patel, Tony Taldone, Chenghua Yang, Weilin Sun, Stefan O. Ochiana
  • Patent number: 10172863
    Abstract: The present application provides substituted purine derivatives and related compounds of the formulas shown. These compounds are useful as inhibitors of HSP90, and hence in the treatment of related diseases. (Formulae) Z1-Z3, Xa-Xc, X2, X4, Y and R are as defined in the specification.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: January 8, 2019
    Assignee: Sloan-Kettering Institute For Cancer Research
    Inventors: Gabriela Chiosis, Tony Taldone, Weilin Sun
  • Patent number: 9926321
    Abstract: The disclosure relates to Compounds of Formulae (IA) and (IB), and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and (IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: March 27, 2018
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Weilin Sun, Tony Taldone, Pallav Patel, Gabriela Chiosis
  • Publication number: 20160310497
    Abstract: The present application provides substituted purine derivatives and related compounds of the formulas shown. These compounds are useful as inhibitors of HSP90, and hence in the treatment of related diseases. (Formulae) Z1-Z3, Xa-Xc, X2, X4, Y and R are as defined in the specification.
    Type: Application
    Filed: April 21, 2016
    Publication date: October 27, 2016
    Inventors: Gabriela Chiosis, Tony Taldone, Weilin Sun
  • Publication number: 20160264577
    Abstract: The disclosure relates to Compounds of Formulae (IA) and (IB), and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and (IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.
    Type: Application
    Filed: May 20, 2016
    Publication date: September 15, 2016
    Inventors: Weilin Sun, Tony Taldone, Pallav Patel, Gabriela Chiosis
  • Publication number: 20160194328
    Abstract: The disclosure relates to novel selective Grp94 inhibitors, compositions comprising an effective amount of such compounds, and methods to treat or prevent a condition, such as cancer, comprising administering to an animal in need thereof an effective amount of such compounds.
    Type: Application
    Filed: August 15, 2014
    Publication date: July 7, 2016
    Inventors: Gabriela Chiosis, Pengrong Yan, Pallav Patel, Hardik J. Patel, Tony Taldone, Chenghua Yang, Weilin Sun, Stefan O. Ochiana
  • Patent number: 9346808
    Abstract: The disclosure relates to Compounds of Formulae (IA) and (IB): and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: May 24, 2016
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Weilin Sun, Tony Taldone, Pallav Patel, Gabriela Chiosis
  • Patent number: 9328114
    Abstract: The present application provides compounds useful in the inhibition of Hsp90, and hence in the treatment of disease.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: May 3, 2016
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Gabriela Chiosis, Tony Taldone, Weilin Sun
  • Publication number: 20140088121
    Abstract: The disclosure relates to Compounds of Formulae (IA) and (IB): and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging.
    Type: Application
    Filed: April 5, 2012
    Publication date: March 27, 2014
    Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: Weilin Sun, Tony Taldone, Pallav Patel, Gabriela Chiosis
  • Publication number: 20120208806
    Abstract: The present application provides compounds useful in the inhibition of Hsp90, and hence in the treatment of disease.
    Type: Application
    Filed: October 7, 2010
    Publication date: August 16, 2012
    Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: Gabriela Chiosis, Tony Taldone, Weilin Sun