Abstract: A multi-stage adjusting damping valve as well as a shock absorber and suspension system using the damping valve are provided. The multi-stage adjusting damping valve comprises a throttle valve, an overflow valve and a multi-stage pilot valve. The multi-stage pilot valve comprises a mechanical regulating valve and a plurality of high-speed switch electromagnetic valves having different throttle hole diameters. The damping valve is connected between a rod cavity and an oil storage cavity of the shock absorber by means of a middle cavity, and the multi-stage damping rapid regulation of the shock absorber is achieved through high-frequency opening and closing of a high-speed switching electromagnetic valve, and in comparison, the machining precision, the manufacturing cost and the control and calibration difficulty of the present disclosure are greatly reduced.

Abstract: A method and system for predicting products of an aromatic hydrocarbon isomerization production process are provided. The method includes generating multiple initial sample points, using a mechanism the actual output response values of all of the initial sample points; establishing an radial basis function (RBF) model according to the initial sample points and actual output response values thereof; using a particle swarm optimization (PSO) algorithm to find expected deviation between nearest neighbors as well as the sampling point having the largest sparsity product, using mechanism model to calculate the output response value of said sampling point on RBF model, adding output response value into the sample points, and reconstructing the surrogate model; repeating the previous step until the upper limit for the number of sample points is reached to obtain a final RBF model; and using the RBF model to predict product yield of aromatic hydrocarbon isomerization.

Abstract: A combined firework is disclosed. In the combined firework, several tubular holes whose central longitudinal axes are parallel to each other are uniformly distributed in a body, the tubular holes have openings upward and bottom ends closed. The closed end of the bottom of each tubular hole is provided with two small through holes penetrating through the bottom of the body and respectively provided with an inward fuse and an outward fuse in series connection. The body, the tubular holes and the small through holes thereof are an integrally molded structure. On the bottom in the tubular hole propellant powder is provided and connected with the outward fuse and the inward fuse. On the propellant powder an inner cylinder or effect powder is provided.

Abstract: The present invention discloses an integral-type combined firework, in which several tubular holes whose central longitudinal axes are parallel to each other are uniformly distributed on a body, the tubular holes have openings upward and bottom ends closed, the closed end of the bottom of each tubular hole is provided with one small through hole that penetrates through the bottom of the body and is provided with a spreading fuse, the body, the tubular holes and the small through holes thereof are an integrally molded structure; the bottom in each tubular holes is provided with propellant powder and connected with the spreading fuse, the propellant powder is provided with an inner cylinder or an effect powder on it.

Abstract: A combined firework is disclosed in the invention. In the combined firework, several tubular holes whose central axes are parallel to each other are uniformly distributed in a body, the tubular holes have openings upward and bottom ends closed, the closed end of the bottom of each tubular hole is provided with two small through holes penetrating through the bottom of the body and respectively provided with an inward fuse and an outward fuse in series connection, the body, the tubular holes and the small through holes thereof are an integral structure moulded in one time; on the bottom in the tubular hole propellant powder is provided and connected with the outward fuse and the inward fuse, on the propellant powder an inner cylinder or effect powder is provided.

Abstract: The present invention discloses an integral-type combined firework, in which several tubular holes whose central axes are parallel to each other are uniformly distributed on a body, the tubular holes have openings upward and bottom ends closed, the closed end of the bottom of each tubular hole is provided with one small through hole that penetrates through the bottom of the body and is provided with a spreading fuse, the body, the tubular holes and the small through holes thereof are an integral structure moulded in one time; the bottom in the tubular holes is provided with propellant powder and connected with the spreading fuse, the propellant powder is provided with an inner cylinder or an effect powder on it.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved “knuckle” of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.

Abstract: A pharmaceutical composition for treating Lyme disease contains an antibody as an active agent which is specific for the 24 kDa antigen (OspC) of B. burgdorferi, preferably an antibody which is specific for the 24 kDa antigen (OspC) of B. burgdorferi having the sequence shown in SEQ ID NO.2.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved “knuckle” of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved “knuckle” of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved "knuckle" of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved "knuckle" of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.

Abstract: HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have purified HNF-4 protein (54 kD) and isolated a cDNA clone encoding the protein. HNF-4 is a member of the steroid hormone receptor superfamily with an unusual amino acid in the conserved "knuckle" of the first zinc finger (DGCKG). This and the fact that HNF-4 does not bind significantly to estrogen, thyroid hormone or glucocorticoid response elements indicate that HNF-4 may represent a new subfamily. HNF-4 binds to its recognition site as a dimer and activates transcription in a sequence-specific fashion in nonhepatic (HeLa) cells. HNF-4 mRNA is present in kidney and intestine as well as liver but is absent in other tissues.