Patents by Inventor Weina Li

Weina Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12258598
    Abstract: A ?-glycosidase SS-BGL mutant for modifying ginsenoside and application thereof are provided, which relate to the field of genetic engineering technologies. The ?-glycosidase SS-BGL mutant is ?-glycosidase SS-BGL with the amino acid sequence as shown in SEQ ID NO: 1 having mutation at one or more sites. A single-site mutation includes: A1, making glutamine at 96th position of SEQ ID NO: 1 to be mutated to glutamic acid; A2, making asparagine at 97th position of SEQ ID NO: 1 to be mutated to aspartate; A3, making asparagine at 128th position of SEQ ID NO: 1 to be mutated to aspartate; A4, making asparagine at 302th position of SEQ ID NO: 1 to be mutated to aspartate. A double-site mutation is a combination of A3 and A4, a three-site mutation is a combination of A1, A2 and A4, and a four-site mutation is a combination of A1, A2, A3 and A4.
    Type: Grant
    Filed: April 18, 2024
    Date of Patent: March 25, 2025
    Assignee: Northwest university
    Inventors: Weina Li, Daidi Fan
  • Publication number: 20240401016
    Abstract: A ?-glycosidase SS-BGL mutant for modifying ginsenoside and application thereof are provided, which relate to the field of genetic engineering technologies. The ?-glycosidase SS-BGL mutant is ?-glycosidase SS-BGL with the amino acid sequence as shown in SEQ ID NO: 1 having mutation at one or more sites. A single-site mutation includes: A1, making glutamine at 96th position of SEQ ID NO: 1 to be mutated to glutamic acid; A2, making asparagine at 97th position of SEQ ID NO: 1 to be mutated to aspartate; A3, making asparagine at 128th position of SEQ ID NO: 1 to be mutated to aspartate; A4, making asparagine at 302th position of SEQ ID NO: 1 to be mutated to aspartate. A double-site mutation is a combination of A3 and A4, a three-site mutation is a combination of A1, A2 and A4, and a four-site mutation is a combination of A1, A2, A3 and A4.
    Type: Application
    Filed: April 18, 2024
    Publication date: December 5, 2024
    Inventors: Weina Li, Daidi Fan
  • Publication number: 20240401093
    Abstract: A ?-glycosidase SS-BGL mutant for modifying ginsenoside and an application thereof are provided, which relate to the field of genetic engineering technologies. The ?-glycosidase SS-BGL mutant is a mutant mutating asparagines at 128th position and 302th position of the amino acid sequence as shown in SEQ ID NO: 1 of ?-glycosidase SS-BGL into aspartic acids respectively. The ?-glucosidase SS-BGL mutant improves the thermal stability of the natural ?-glucosidase SS-BGL at extremely high temperature, and is more conducive to the application of SS-BGL in ginsenoside preparation.
    Type: Application
    Filed: May 28, 2024
    Publication date: December 5, 2024
    Inventors: Weina Li, Daidi Fan
  • Patent number: 12134829
    Abstract: A sealing process includes applying a first reactant to a substrate having a porous structure, the first reactant comprising a chromium (III) precursor and a transition metal precursor and applying a second reactant to the first reactant, the second reactant comprising a rare earth element precursor and an alkaline earth element precursor to form reservoirs of trivalent chromium in pore space of the porous structure, and a physical barrier over the substrate and the reservoirs.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 5, 2024
    Assignee: RTX CORPORATION
    Inventors: Bart Antonie van Hassel, Georgios S. Zafiris, Zhongfen Ding, Michael A. Kryzman, Mark R. Jaworowski, Weina Li, Blair A. Smith, Weilong Zhang, Promila Bhaatia
  • Patent number: 12134789
    Abstract: A glycosyltransferase BS-YjiC mutant, a construction method and an application thereof provided, relating to the field of genetic engineering technologies. The glycosyltransferase BS-YjiC mutant is obtained by performing site-directed mutation on amino acids at the 125th, 178th, 313th, 125th and 178th, or 125th and 313th positions of a wild-type glycosyltransferase BS-YjiC with the amino acid sequence as shown in SEQ ID NO: 1. Compared with the wild-type glycosyltransferase BS-YjiC, the glycosyltransferase BS-YjiC mutant is more suitable for catalyzing protopanaxadiol (PPD) to generate rare ginsenosides F12 and Rh2, which is more conducive to the flexibility of the production process.
    Type: Grant
    Filed: March 25, 2024
    Date of Patent: November 5, 2024
    Assignee: Northwest university
    Inventors: Weina Li, Daidi Fan, Chenhui Zhu
  • Publication number: 20240318153
    Abstract: A glycosyltransferase BS-YjiC mutant, a construction method and an application thereof provided, relating to the field of genetic engineering technologies. The glycosyltransferase BS-YjiC mutant is obtained by performing site-directed mutation on amino acids at the 125th, 178th, 313th, 125th and 178th, or 125th and 313th positions of a wild-type glycosyltransferase BS-YjiC with the amino acid sequence as shown in SEQ ID NO: 1. Compared with the wild-type glycosyltransferase BS-YjiC, the glycosyltransferase BS-YjiC mutant is more suitable for catalyzing protopanaxadiol (PPD) to generate rare ginsenosides F12 and Rh2, which is more conducive to the flexibility of the production process.
    Type: Application
    Filed: March 25, 2024
    Publication date: September 26, 2024
    Inventors: Weina Li, Daidi Fan, Chenhui Zhu
  • Patent number: 11959178
    Abstract: A method is disclosed for treating an anodized metal surface. According to the method, polynuclear clusters comprising aluminum oxide hydroxide are applied to the anodized metal surface.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: April 16, 2024
    Assignee: HAMILTON SUNDSTRAND CORPORATION
    Inventors: Susanne M. Opalka, Weina Li, Joseph J. Sangiovanni, Mark R. Jaworowski, Georgios S. Zafiris, Weilong Zhang, Zhongfen Ding
  • Patent number: 11906814
    Abstract: The present disclosure provides a prime lens module and an in-vehicle camera system. From an object side to an imaging side thereof, the prime lens module sequentially includes: a first lens with a negative focal power, a second lens with a negative focal power, a third lens with a positive focal power, a fourth lens with a positive focal power, a fifth lens with a positive focal power, a sixth lens with a negative focal power, and a seventh lens with a positive focal power. The first lens is a meniscus spherical lens. The second lens is a biconcave spherical lens. The third lens is a biconvex spherical lens and bonded to the second lens. The fourth lens is a biconvex spherical lens or a biconvex aspheric lens. The fifth lens is a biconvex spherical lens. The sixth lens is a biconcave spherical lens and bonded to the fifth lens.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: February 20, 2024
    Assignee: JIANGXI LIANCHUANG ELECTRONIC CO., LTD.
    Inventors: Bo Gao, Weina Li, Jianxin Huang, Jian Han
  • Publication number: 20230364458
    Abstract: Methods and operations for controlling effective delivery of fire suppressant are disclosed. The fire suppression system comprises a control valve operatively coupled with a cylinder containing a fire suppressant. The system comprises a controller operatively coupled with the control valve. The controller is configured to command the control valve to open, discharging a flow of the fire suppressant at a first flow rate; and adjust the flow of the fire suppressant to a second flow rate during the discharge.
    Type: Application
    Filed: April 16, 2023
    Publication date: November 16, 2023
    Inventors: Weina Li, Richard L. Lupien, Thomas Carl Kjellman
  • Patent number: 11807779
    Abstract: A method of applying a trivalent chromium or chromium-free conversion coating to a metallic substrate including mixing a dye compound that interacts with electromagnetic radiation outside the human visual spectrum but not electromagnetic radiation that is within the human visual spectrum to produce an observable emission into the trivalent chromium or chromium-free conversion coating mixture to allow for inspection of the coating after applied with a correlating electromagnetic radiation source.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: November 7, 2023
    Assignee: HAMILTON SUNDSTRAND CORPORATION
    Inventors: Sean C. Emerson, Blair A. Smith, Weina Li, Georgios S. Zafiris, Bart Antonie Van Hassel
  • Publication number: 20230203145
    Abstract: The present application discloses two anti-GDF15 neutralizing monoclonal antibodies and uses thereof. The variable regions of the light chain and heavy chain of the antibodies G1 and G2 with neutralizing activity are provided. Anti-GDF15 mouse monoclonal antibodies were prepared by the hybridoma technology, anti-GDF15 hybridoma cell lines capable of stable secretion with high specificity were screened out, ascites were prepared to obtain high-specificity and high-affinity anti-GDF15 monoclonal antibodies and two anti-GDF15 monoclonal antibodies with neutralizing activity were identified for the first time by constructing an antibody neutralization detection system.
    Type: Application
    Filed: September 30, 2022
    Publication date: June 29, 2023
    Inventors: Yingqi ZHANG, Meng LI, Chuanyang XU, Zhaowei WANG, Weina LI, Lei HE, Cun ZHANG, Qiang HAO, Ning ZHAO
  • Publication number: 20230141706
    Abstract: Disclosed herein is a process for coating a component, comprising applying a bond coat on a substrate of a component; applying a thermal barrier material to the bond coat; and applying a coating containing polynuclear aluminum oxide/hydroxide clusters, to the thermal barrier material. Disclosed herein too is a gas turbine engine component, comprising a superalloy substrate; a bond coat on the substrate; a thermal barrier material on the bond coat; and a coating containing polynuclear aluminum oxide/hydroxide clusters on the thermal barrier material.
    Type: Application
    Filed: April 5, 2021
    Publication date: May 11, 2023
    Inventors: Susanne M. Opalka, Weina Li
  • Publication number: 20230084990
    Abstract: A fire extinguisher includes a cylinder for storing a fire extinguishing agent; a valve assembly disposed on the cylinder, the valve assembly comprising a closed position and an open position, the valve assembly configured to deliver the fire extinguishing agent from within the cylinder when in the open position; and an actuation assembly operably connected to the valve assembly, the actuation assembly comprising a button and a control device, the control device configured to actuate the valve assembly from the closed position to the open position when the button is contacted.
    Type: Application
    Filed: September 12, 2022
    Publication date: March 16, 2023
    Inventors: Weina Li, Christopher Fergusson, Slade Culp
  • Publication number: 20230012877
    Abstract: A method is disclosed for treating an anodized metal surface. According to the method, polynuclear clusters comprising aluminum oxide hydroxide are applied to the anodized metal surface.
    Type: Application
    Filed: September 27, 2022
    Publication date: January 19, 2023
    Inventors: Susanne M. Opalka, Weina Li, Joseph J. Sangiovanni, Mark R. Jaworowski, Georgios S. Zafiris, Weilong Zhang, Zhongfen Ding
  • Patent number: 11473201
    Abstract: A method is disclosed for treating an anodized metal surface. According to the method, polynuclear clusters comprising aluminum oxide hydroxide are applied to the anodized metal surface.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: October 18, 2022
    Assignee: HAMILTON SUNDSTRAND CORPORATION
    Inventors: Susanne M. Opalka, Weina Li, Joseph J. Sangiovanni, Mark R. Jaworowski, Georgios S. Zafiris, Weilong Zhang, Zhongfen Ding
  • Patent number: 11453955
    Abstract: A nanocellular single crystal nickel based material is provided having a thermal diffusivity in the range of 0.0002 cm{circumflex over (?)}2/s to 0.02 cm{circumflex over (?)}2/s and a thermal conductivity in the range of 0.024 W/mK to 9.4 W/mK. The nanocellular single crystal nickel based material may be used to form turbine engine components. The nanocellular single crystal nickel based material may be produced by providing a first solution containing a nickel precursor and deionized water, providing a second solution containing a structure controlling polymer/surfactant and an alcohol, mixing the first and second solutions into a solution containing a reducing agent to form a third solution, and processing the third solution to create the nanocellular single crystal based material.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: September 27, 2022
    Assignee: Raytheon Technologies Corporation
    Inventors: Michael J. Birnkrant, Weina Li
  • Patent number: 11199686
    Abstract: A wide-angle lens in the following order from an object side toward an image plane includes: a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, a seventh lens, an optical reflecting member, and an optical filter. The first lens has negative refractive power and a concave image side surface. The second lens has negative refractive power and a concave image side surface. The third lens has positive refractive power. The fourth lens has positive refractive power and a concave image side surface. The fifth lens has negative refractive power, a concave object side surface, and a concave image side surface. The sixth lens has positive refractive power, a convex object side surface, and a convex image side surface. The seventh lens has positive refractive power, a convex object side surface, and a convex image side surface. Each of the first lens and the third lens is a spherical lens.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: December 14, 2021
    Assignee: JIANGXI LIANCHUANG ELECTRONIC CO., LTD.
    Inventors: Weina Li, Bo Gao, Jian Han, Jiyong Zeng
  • Publication number: 20210356719
    Abstract: A wide-angle lens in the following order from an object side toward an image plane includes: a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, a seventh lens, an optical reflecting member, and an optical filter. The first lens has negative refractive power and a concave image side surface. The second lens has negative refractive power and a concave image side surface. The third lens has positive refractive power. The fourth lens has positive refractive power and a concave image side surface. The fifth lens has negative refractive power, a concave object side surface, and a concave image side surface. The sixth lens has positive refractive power, a convex object side surface, and a convex image side surface. The seventh lens has positive refractive power, a convex object side surface, and a convex image side surface. Each of the first lens and the third lens is a spherical lens.
    Type: Application
    Filed: November 14, 2018
    Publication date: November 18, 2021
    Inventors: WEINA LI, BO GAO, JIAN HAN, JIYONG ZENG
  • Publication number: 20210332249
    Abstract: A method of applying a trivalent chromium or chromium-free conversion coating to a metallic substrate including mixing a dye compound that interacts with electromagnetic radiation outside the human visual spectrum but not electromagnetic radiation that is within the human visual spectrum to produce an observable emission into the trivalent chromium or chromium-free conversion coating mixture to allow for inspection of the coating after applied with a correlating electromagnetic radiation source.
    Type: Application
    Filed: July 8, 2021
    Publication date: October 28, 2021
    Inventors: Sean C. Emerson, Blair A. Smith, Weina Li, Georgios S. Zafiris, Bart Antonie Van Hassel
  • Patent number: 11125102
    Abstract: A method of manufacturing a gas turbine engine air seal comprising forming at least one MAX phase particle. The method includes coating the at least one MAX phase particle with a metallic shell. The method includes applying the at least one MAX phase metallic coated particle to a surface of a substrate of the air seal to form an abradable layer of a MAXMET composite abradable material from the at least on MAX phase metallic coated particle.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: September 21, 2021
    Assignee: Raytheon Technologies Corporation
    Inventors: Shahram Amini, Christopher W. Strock, Weina Li