Patents by Inventor Weipeng Zhang

Weipeng Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20250122191
    Abstract: Provided are certain BCL-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 10, 2022
    Publication date: April 17, 2025
    Inventors: Hongbin LIU, Hua XU, Weipeng ZHANG, Rui TAN, Jinhua YU, Yunling WANG, Yangli QI, Yue RONG, Zhuo HUANG, Ling CHEN, Chenglin ZHOU, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Measurement system for micro-mixing and measurement method thereof
    Patent number: 12181417
    Abstract: Disclosed are a measurement system for micro-mixing and a measurement method thereof. The measurement system comprises a mixing device, a light enhancement unit, an observation unit, an image acquisition unit, a display device and a tracer injection device; the light enhancement unit comprises a light-emitting device, a light-focusing device and a reflecting device; the observation unit comprises an observation window; the image acquisition unit comprises a distortion-free lens and an image acquisition device which are connected in sequence, and a central axis of the distortion-free lens is in alignment with a central axis of the observation window. The measurement method is performed in the measurement system provided by the present application. In the present application, the brightness of visual field is improved, the light interference on target image is shielded off, the process of micro-mixing can be observed in real time, and thereby the micro-mixing efficiency can be evaluated.
    Type: Grant
    Filed: January 25, 2024
    Date of Patent: December 31, 2024
    Assignees: INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES, NANJING JIUZHANG CHEMICAL TECHNOLOGY CO., LTD., ZHEJIANG GREATWALL MIXERS CO., LTD.
    Inventors: Chao Yang, Xiaoxia Duan, Xin Feng, Dingwang Huang, Jie Chen, Weipeng Zhang, Zheng Li, Yuanyuan Li, Zaisha Mao, Minghui Xie
  • MEASUREMENT SYSTEM FOR MICRO-MIXING AND MEASUREMENT METHOD THEREOF
    Publication number: 20240310289
    Abstract: Disclosed are a measurement system for micro-mixing and a measurement method thereof. The measurement system comprises a mixing device, a light enhancement unit, an observation unit, an image acquisition unit, a display device and a tracer injection device; the light enhancement unit comprises a light-emitting device, a light-focusing device and a reflecting device; the observation unit comprises an observation window; the image acquisition unit comprises a distortion-free lens and an image acquisition device which are connected in sequence, and a central axis of the distortion-free lens is in alignment with a central axis of the observation window. The measurement method is performed in the measurement system provided by the present application. In the present application, the brightness of visual field is improved, the light interference on target image is shielded off, the process of micro-mixing can be observed in real time, and thereby the micro-mixing efficiency can be evaluated.
    Type: Application
    Filed: January 25, 2024
    Publication date: September 19, 2024
    Inventors: Chao YANG, Xiaoxia DUAN, Xin FENG, Dingwang HUANG, Jie CHEN, Weipeng ZHANG, Zheng LI, Yuanyuan LI, Zaisha MAO, Minghui XIE
  • Method for preparing soft magnetic manganese-zinc ferrite composite by removing impurities from industrial waste step by step
    Patent number: 12065360
    Abstract: Provided is a method for preparing a soft magnetic manganese-zinc ferrite composite by removing impurities from industrial waste step by step. Manganese-containing waste residue is crushed and dried, and then mixed with a flux in a muffle furnace and roasted at a temperature below 1000° C. till solid-liquid stratification; then, multi-step impurity removal is performed to obtain a high-purity quaternary purification solution of manganese sulfate. Similarly, zinc residue is melted to remove impurities, and then multi-step impurity removal is performed to obtain a high-purity quaternary purification solution of zinc sulfate. According to a manganese-zinc-iron ratio required for the manganese-zinc ferrite, the two purification solutions are mixed, and ferrous sulfate is added.
    Type: Grant
    Filed: December 13, 2023
    Date of Patent: August 20, 2024
    Assignee: CHONGQING SHANGJIA ELECTRONIC CO., LTD.
    Inventors: Shuchun Li, Liang Fu, Xinren Liao, Juncai Ma, Ping Li, Zhan Xu, Weipeng Zhang
  • Method for synchronous production of manganese tetraoxide and ferric oxide for soft magnetic material by using marine polymetallic nodules
    Patent number: 11791078
    Abstract: A method for synchronous production of manganese tetraoxide and ferric oxide for a soft magnetic material by using marine polymetallic nodules includes: 1) crushing and grinding marine manganese nodules and baking to a constant weight; thoroughly mixing with a mixed flux and roasting in a muffle furnace; 2) carrying out solid-liquid separation, washing solid-phase precipitates with water, grinding the solid, adding sulfuric acid, controlling the temperature to be below 50° C., and vacuuming a reactor up; 3) adding a reducing agent to react at room temperature for 5-10 min, adding ammonia water to adjust the pH value to 5.5, and carrying out separation and filtering; 4) controlling the temperatures of manganese sulfate and ferric sulfate solutions to be below 50° C., and adding ammonium sulfide; and 5) washing with deionized water, and calcining at 800-900° C. for 1-3 s by a suspension low-temperature instantaneous firing system.
    Type: Grant
    Filed: May 11, 2023
    Date of Patent: October 17, 2023
    Assignees: CHONGQING SHANGJIA ELECTRONIC CO., LTD., CHONGQING UNIVERSITY
    Inventors: Shuchun Li, Liang Fu, Fusheng Pan, Xinren Liao, Hualin Xie, Juncai Ma, Ping Li, Zhan Xu, Weipeng Zhang
  • COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20230174556
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 8, 2023
    Inventors: Zuwen ZHOU, Rui TAN, Hua XU, Qihong LIU, Huajie ZHANG, Bin LIU, Weipeng ZHANG, Zhifu LI, Yanxin LIU, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20230159527
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 7, 2021
    Publication date: May 25, 2023
    Inventors: Weipeng ZHANG, Hongbin LIU, Rui TAN, Zhifu LI, Yue RONG, Qihong LIU, Zhifang CHEN, Ling CHEN, Hua XU, Zuwen ZHOU, Jinhua YU, Haohan TAN, Bin LIU, Yunling WANG, Lijun YANG, Chengxi HE, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Macrocyclic compounds as TRK kinases inhibitors
    Patent number: 11555042
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 17, 2023
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Huajie Zhang, Qihong Liu, Chengxi He, Weipeng Zhang, Rui Tan, Bin Liu, Hong Fu, Haohan Tan, Lijun Yang, Hongbin Liu, Yunling Wang, Yuwei Gao, Zongyao Zou, Yanxin Liu, Shu Lin, Tongshuang Li, Xingdong Zhao, Weibo Wang
  • Deuterated compounds as rock inhibitors
    Patent number: 11485707
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds thereof, and use of these compounds in preparing drugs for inhibiting ROCK.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 1, 2022
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Rui Tan, Weipeng Zhang, Yunling Wang, Xingdong Zhao, Tao Cheng, Shu Lin, Weibo Wang
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3,4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20220235049
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 1, 2020
    Publication date: July 28, 2022
    Inventors: Haohan TAN, Qihong LIU, Bin LIU, Zhifu LI, Xianlong WANG, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Yanxin LIU, Zongyao ZOU, Shu LIN, Kai YU, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
    Publication number: 20220041588
    Abstract: Provided are certain RET inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 26, 2019
    Publication date: February 10, 2022
    Inventors: Chengxi HE, Rui TAN, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Qihong LIU, Xingdong ZHAO, Yanxin LIU, Yuwei GAO, Shu LIN, Weibo WANG
  • Compounds as BLC-2-selective apoptosis-inducing agents
    Patent number: 11053239
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bcl-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 6, 2021
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Zuwen Zhou, Chengxi He, Zhifu Li, Yue Rong, Rui Tan, Huajie Zhang, Hongbin Liu, Weipeng Zhang, Haohan Tan, Zhifang Chen, Lihua Jiang, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210139506
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: May 13, 2021
    Applicants: Fochon Pharmaceuticals, Ltd., Shanghai Fochon Pharmaceutical Co., LTD.
    Inventors: Huajie ZHANG, Qihong LIU, Chengxi HE, Weipeng ZHANG, Rui TAN, Bin LIU, Hong FU, Haohan TAN, Lijun YANG, Hongbin LIU, Yunling WANG, Yuwei GAO, Zongyao ZOU, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • DEUTERATED COMPOUNDS AS ROCK INHIBITORS
    Publication number: 20210070711
    Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds thereof, and use of these compounds in preparing drugs for inhibiting ROCK.
    Type: Application
    Filed: March 22, 2019
    Publication date: March 11, 2021
    Inventors: Rui TAN, Weipeng ZHANG, Yunling WANG, Xingdong ZHAO, Tao CHENG, Shu LIN, Weibo WANG
  • Indolizine derivatives, composition and methods of use
    Patent number: 10894038
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: January 19, 2021
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO. LTD., FOCHON PHARMACEUTICALS, LTD.
    Inventors: Tongshuang Li, Xingdong Zhao, Chuiliang Yu, Haohan Tan, Xianlong Wang, Rui Tan, Bin Liu, Weipeng Zhang, Huajie Zhang, Qihong Liu, Zuwen Zhou, Zhifu Li, Yue Rong, Jing Sun, Weibo Wang
  • Neural network training
    Patent number: 10839226
    Abstract: Techniques for neural network training are provided. One computer-implemented method comprises: obtaining, by an electronic device operatively coupled to a processing unit, based on a similarity between two images, a first image and a second image. The computer-implemented method also comprises training, by the electronic device, a neural network based on the first image and the second image such that a distance between a first vector and a second vector generated respectively from the first image and the second image in the trained neural network is associated with the similarity.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: November 17, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen Mingyu Chu, Peng Gao, Chang Sheng Li, Dong Sheng Li, Junchi Yan, Weipeng Zhang
  • Model based data processing
    Patent number: 10832162
    Abstract: Techniques for model based data processing are proposed. In one example, a computer-implemented method is as follows. A first model is determined from a first category of data processing models and a second model is determined from a second category of data processing models. The second category can be different from the first category in some instances. Performance of a first combined model of the first and second models can be compared with performance of the first model. A target model for processing data can be selected from the first combined model and the first model based on the comparing.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: November 10, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Boliang Chen, Stephen Mingyu Chu, Jing Chang Huang, Dong Sheng Li, Junchi Yan, Weipeng Zhang
  • Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors
    Patent number: 10800785
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: October 13, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Weipeng Zhang, Zhifang Chen, Ling Chen, Xianlong Wang, Zhifu Li, Rui Tan, Lijun Yang, Haohan Tan, Bin Liu, Kai Ran, Zongyao Zou, Min Lin, Jing Sun, Weibo Wang
  • Discovery of cationic nonribosomal peptides as Gram-negative antibiotics through global genome mining
    Patent number: 10738093
    Abstract: Pharmacological compositions comprising a cationic nonribosomal peptide (CNRP) or a salt thereof are described. Further, methods of treating a bacterial infection in a subject by administering to the subject a CNRP or a salt thereof are provided.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: August 11, 2020
    Assignees: The Hong Kong University of Science and Technology, China Ocean Mineral Resources R&D Assocation (COMRA)
    Inventors: Pei-Yuan Qian, Yongxin Li, Zheng Zhong, Weipeng Zhang
  • INDOLIZINE DERIVATIVES, COMPOSITION AND METHODS OF USE
    Publication number: 20200113876
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: December 26, 2016
    Publication date: April 16, 2020
    Inventors: Tonshuang LI, Xingdong ZHAO, Chuiliang YU, Haohan TAN, Xianlong WANG, Rui TAN, BIN LIU, Weipeng ZHANG, Huajie ZHANG, Qihong LIU, Zuwen ZHOU, Zhifu LI, Yue RONG, Jing SUN, Weibo WANG