Abstract: A short-distance optical amplification module and a near-eye display optical module using the same in the present invention relates to an optical amplification module applicable for short distance and an optical module using the same for near-eye display. The purpose of the present invention is to provide an optical amplification module for large-multiple amplification within a short distance (less than 5 cm) and a near-eye display optical module using the same to achieve super large field of view within a short distance (less than 3 cm). The short-distance optical amplification module in the present invention comprises a first 45 degree phase delay sheet (2), a partial-transmission and partial-reflection curved lens (4), a second 45 degree phase delay sheet (5) and a reflective polarizing sheet (6) which are sequentially arranged.

Abstract: A short-distance optical amplification module and a near-eye display optical module using the same in the present invention relates to an optical amplification module applicable for short distance and an optical module using the same for near-eye display. The purpose of the present invention is to provide an optical amplification module for large-multiple amplification within a short distance (less than 5 cm) and a near-eye display optical module using the same to achieve super large field of view within a short distance (less than 3 cm). The short-distance optical amplification module in the present invention comprises a first 45 degree phase delay sheet (2), a partial-transmission and partial-reflection curved lens (4), a second 45 degree phase delay sheet (5) and a reflective polarizing sheet (6) which are sequentially arranged.

Abstract: A short-distance optical amplification module and a near-eye display optical module using the same in the present invention relates to an optical amplification module applicable for short distance and an optical module using the same for near-eye display. The purpose of the present invention is to provide an optical amplification module for large-multiple amplification within a short distance (less than 5 cm) and a near-eye display optical module using the same to achieve super large field of view within a short distance (less than 3 cm). The short-distance optical amplification module in the present invention comprises a first 45 degree phase delay sheet (2), a partial-transmission and partial-reflection curved lens (4), a second 45 degree phase delay sheet (5) and a reflective polarizing sheet (6) which are sequentially arranged.

Abstract: The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.

Abstract: A bi-sensing optical system capable of transmitting signals for eye and object tracking and/or detection, and/or capable of transmitting signals comprising visible light to an eye of a user and non-visible light for eye tracking and object detection and/or tracking is disclosed herein.

Abstract: Described is a method to make diindolylmethanes and indolyl/pyrrolylmethanes, The method includes the steps of contacting an ether comprising an arylpropargyl moiety and an amine-protected, substituted or unsubstituted aniline moiety with a substituted or unsubstituted indol or a substituted or unsubstituted pyrrole, in the presence of a metal-containing catalyst, for a time and at a temperature to cause an annulation/arylation cascade reaction that yields a diindolylmethane or a indolyl/pyrrolylmethane. The resulting compounds are effective to modulate activity of arylhydrocarbon receptors, to inhibit activity of PCSK9, and to stimulate secretion of glucagon-like peptide 1 in mammals.

Abstract: Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentiated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells.

Abstract: A bi-sensing optical system capable of transmitting signals for eye and object tracking and/or detection, and/or capable of transmitting signals comprising visible light to an eye of a user and non-visible light for eye tracking and object detection and/or tracking is disclosed herein.

Abstract: A stator, a motor and a compressor are provided. A stator applied to a motor includes: a stator iron core; a plurality of stator teeth extending inwards along a radial direction of the stator; stator slots distributed between the plurality of stator teeth; and a winding wound around the stator teeth to generate a rotating magnetic field, where at least one phase of winding or a coil forming the at least one phase of winding is formed by different wires, and the different wires are connected in a serial or serial-parallel manner to form the coil or the least one phase winding.

Abstract: The present invention provides a stator, a three-phase induction motor and a compressor. The stator is applied to a three-phase induction motor of a compressor. The stator includes: a stator iron core; a plurality of stator teeth extending inwards along a radial direction of the stator; stator slots distributed between the plurality of stator teeth; and three phases of windings wound around the stator teeth to generate a rotating magnetic field, where a coil of each phase of winding in the three phases of windings is made of a composite wire. The composite wire includes a wire core made of a first conductive metal material, and an outer layer wrapping an outer circumferential surface of the wire core and made of a second conductive metal material, wherein the first conductive metal material and the second conductive metal material have different electrical conductivities.

Abstract: Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentiated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells.

Abstract: In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.

Abstract: Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentiated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells.

Abstract: The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.

Abstract: Certain embodiments disclosed herein are directed to a method of producing endoderm cells, such as definitive endoderm cells by exposing stem cells such as embryonic stem cells or induced pluripotent stem (iPS) cells to an effective amount of at least one compound described herein to differentiate the stem cells into the endoderm cells such as definitive endoderm cells. Differentated endoderm cells produced by the methods disclosed herein can be differentiated into pancreatic epithelium, and other endoderm derivatives such as thymus, liver, stomach, intestine and lung. Another aspect of the present invention relates to a method of producing pancreatic progenitor cells, such as Pdx1-positive pancreatic progenitor cells by exposing endoderm cells, such as definitive endoderm cells to an effective amount of at least one compound described herein to differentiate the definitive endoderm cells into Pdx1-positive pancreatic progenitor cells.

Abstract: Multiple image projection apparatus are described. A cubic multi-prism beam splitter is provided having diagonal interfaces with one or more PBS elements and/or reflective elements positioned thereon. At least first and second spatial light modulators, such as LCoS SLMs, are positioned adjacent the beam splitter cube. The first and second LCoS spatial light modulators and first and second projection optics systems are configured to output a first modulated image from the first LCoS SLM to the first projection optics system and a second modulated image from the second LCoS spatial light modulator to the second projection optics system. In other embodiments, additional LCoS spatial light modulators and light sources produce 3-D images. Addition of sensors permits user interaction with a projected image which is fed back to a controller to optionally change current or future images displayed by the system.

Abstract: The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.

Abstract: An interactive projection device includes a light source configured to emit an input light beam, wherein the light source comprises a visible light emitting device; a first beam splitter configured to split the input light beam into first and second split light beams; a second beam splitter configured to split a scattered light beam received from a surface into third and fourth split light beams; an image forming device configured to produce an image light beam based on the first split light beam and emit the image light beam onto the surface through the first and second splitters, thereby generating a projection image on the surface; and a detector configured to detect the invisible light of the third split light beam, thereby acquiring a scattering image from the surface.

Abstract: In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.

Abstract: Multiple image projection apparatus are described. A cubic multi-prism beam splitter is provided having diagonal interfaces with one or more PBS elements and/or reflective elements positioned thereon. At least first and second spatial light modulators, such as LCoS SLMs, are positioned adjacent the beam splitter cube. The first and second LCoS spatial light modulators and first and second projection optics systems are configured to output a first modulated image from the first LCoS SLM to the first projection optics system and a second modulated image from the second LCoS spatial light modulator to the second projection optics system. In other embodiments, additional LCoS spatial light modulators and light sources produce 3-D images. Addition of sensors permits user interaction with a projected image which is fed back to a controller to optionally change current or future images displayed by the system.