Abstract: The present invention discloses a drug for the augmentation treatment of myocardial infarction with stem cells and its application, specifically the application of 2-deoxy-D-glucose in the preparation of drugs for the augmentation treatment of myocardial infarction with stem cells. Animal experiments have confirmed that the injection of 2-deoxy-D-glucose increased the survival rate of injected mesenchymal stem cells and enhanced the therapeutic effect of mesenchymal stem cells.

Abstract: A stem cell agent for anti-hypoxia injury and its preparation method, and its application in the drugs for the therapy of acute myocardial infarction. The preparation method for the stem cell agent for anti-hypoxia injury comprises mixed stem cells and a liquid of lentivirus with Fstl1 over-expression in a medium to obtain the stem cell agent for anti-hypoxia injury. The Fstl1 modified MSCs provided by the present invention have anti-hypoxia injury capability, can improve transplant survival rate, and can improve the cardiac function after infarction by means of direct injection into the cardiac muscle.