Patents by Inventor Weiqin Jiang

Weiqin Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives as selective androgen receptor modulator (SARMS)
    Patent number: 7288553
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 30, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Indole derivatives as selective androgen receptor modulators (SARMS)
    Patent number: 7282507
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 16, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: James C. Lanter, Zhihua Sui, James J. Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • 11-PHOSPHOROUS STEROID DERIVATIVES USEFUL AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20070232570
    Abstract: The present invention is directed to novel 11-phosphorous steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by a progesterone or glucocorticoid receptor.
    Type: Application
    Filed: February 16, 2007
    Publication date: October 4, 2007
    Inventors: James Fiordeliso, Weiqin Jiang, Zhihua Sui
  • 17-PHOSPHOROUS STEROID DERIVATIVES USEFUL AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20070207982
    Abstract: The present invention is directed to novel 17-phosphorous steroid derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by a progesterone or glucocorticoid receptor.
    Type: Application
    Filed: February 16, 2007
    Publication date: September 6, 2007
    Inventors: Weiqin Jiang, Zhihua Sui
  • INDOLE DERIVATIVES USEFUL AS PROGESTERONE RECEPTOR MODULATORS
    Publication number: 20070135511
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.
    Type: Application
    Filed: January 16, 2007
    Publication date: June 14, 2007
    Inventors: Weiqin Jiang, James Fiordeliso, Zhihua Sui
  • Indole derivatives useful as progesterone receptor modulators
    Patent number: 7183309
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: February 27, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • Indole derivatives useful as progesterone receptor modulators
    Publication number: 20060111427
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical uses of these compounds are related to contraception, the treatment and/or prevention of secondary amenorrhea, dysfunctional bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon, prostate, or minication of side effects of cyclid menstrual bleeding. Additional uses of the invention include stimulation of food intake.
    Type: Application
    Filed: October 21, 2005
    Publication date: May 25, 2006
    Inventors: Weiqin Jiang, James Fiordeliso, Zhihua Sui
  • Pyridine imidazoles and aza-indoles as progesterone receptor modulators
    Publication number: 20060111391
    Abstract: The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatment of disorders associated with the depletion of estrogen such as hot flashes, vaginal dryness, osteopenia and osteoporosis; hormone sensitive cancers and hyperplasia of the breast, endometrium, cervix and prostate; endometriosis, uterine fibroids, osteoarthritis and as contraceptive agents, alone or in combination with a progestogen or progestogen antagonist.
    Type: Application
    Filed: October 21, 2005
    Publication date: May 25, 2006
    Inventors: Weiqin Jiang, James J. Fiordeliso, Zhihua Sui
  • Trisubstituted thiophenes as progesterone receptor modulators
    Publication number: 20060106047
    Abstract: The present invention is directed to novel trisubstituted thiophene derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these compounds are related to hormonal contraception, the treatment and/or prevention of secondary dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon or prostate. Additional uses of the invention include stimulation of food intake.
    Type: Application
    Filed: October 21, 2005
    Publication date: May 18, 2006
    Inventors: Weiqin Jiang, James Fiordeliso, Zhihua Sui
  • Novel indole derivatives as selective androgen receptor modulators (SARMS)
    Publication number: 20050250741
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: April 1, 2005
    Publication date: November 10, 2005
    Inventors: James Lanter, Zhihua Sui, James Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Novel indole derivatives as selective androgen receptor modulator (SARMS)
    Publication number: 20050250740
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: April 1, 2005
    Publication date: November 10, 2005
    Inventors: James Lanter, Zhihua Sui, James Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Novel indole derivatives as selective androgen receptor modulators (SARMS)
    Publication number: 20050245485
    Abstract: The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
    Type: Application
    Filed: April 1, 2005
    Publication date: November 3, 2005
    Inventors: James Lanter, Zhihua Sui, James Fiordeliso, Weiqin Jiang, Xuqing Zhang
  • Substituted 2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one derivatives useful as phosphodiesterase inhibitors
    Patent number: 6800625
    Abstract: The invention relates to novel 2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one derivatives of the formula (I) and (IV): wherein all variables are as herein defined, pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: October 5, 2004
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Weiqin Jiang, Zhihua Sui
  • Substituted tetracyclic pyrroloquinolone derivatives useful as phosphodiesterase inhibitors
    Patent number: 6686349
    Abstract: The invention relates to novel tetracyclic pyrroloquinolone derivatives of the formula (I) or (II): wherein all variables are as herein defined, pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: February 3, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Weiqin Jiang, Zhihua Sui
  • SUBSTITUTED 2,4-DIHYDRO-PYRROLO[3,4-B]QUINOLIN-9-ONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20040006079
    Abstract: The invention relates to novel 2,4-dihydro-pyrrolo[3,4-b]quinolin-9-one derivatives of the formula (I) and (IV): 1
    Type: Application
    Filed: June 17, 2003
    Publication date: January 8, 2004
    Inventors: Weiqin Jiang, Zhihua Sui
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Patent number: 6635638
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): pharmaceutical compositions containing the compounds and their use for the treatment of sexual dysfunction.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: October 21, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weiqin Jiang, James C. Lanter
  • Substituted tetracyclic pyrroloquinolone derivatives useful as phosphodiesterase inhibitors
    Publication number: 20030144268
    Abstract: The invention relates to novel tetracyclic pyrroloquinolone derivatives of the formula (I) or (II): 1
    Type: Application
    Filed: November 12, 2002
    Publication date: July 31, 2003
    Inventors: Weiqin Jiang, Zhihua Sui
  • Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
    Publication number: 20020010183
    Abstract: The invention relates to novel pyrrolopyridinone derivatives of the formula (I) or (II): 1
    Type: Application
    Filed: May 2, 2001
    Publication date: January 24, 2002
    Inventors: Zhihua Sui, Mark J. Macielag, Jihua Guan, Weiqin Jiang, James C. Lanter