Abstract: A communication method, system, device and computer-readable storage medium are applicable to a Windows system. The method involves: determining a media file used when communicating through a message queue; acquiring identification information of a communication sender; and adding the identification information to an access control list of the media file, such that the communication sender can access the media file, so that the communication sender can communicate through the message queue. Identification information of the communication sender is added to the access control list of the media file, increasing the probability that the communication sender successfully accesses the media file, and thereby improving the success rate of the communication sender through the message queue, and improving the communication stability of the Windows system.

Abstract: A communication method, system, device and computer-readable storage medium are applicable to a Windows system. The method involves: determining a media file used when communicating through a message queue; acquiring identification information of a communication sender; and adding the identification information to an access control list of the media file, such that the communication sender can access the media file, so that the communication sender can communicate through the message queue. Identification information of the communication sender is added to the access control list of the media file, increasing the probability that the communication sender successfully accesses the media file, and thereby improving the success rate of the communication sender through the message queue, and improving the communication stability of the Windows system.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, and including a first coil portion extending around a first one of the plurality of teeth and a second coil portion extending around a second one of the plurality of teeth. The stator assembly further includes a plurality of connection portions including a first connection portion extending between the first coil portion and the second coil portion and electrically coupling the first coil portion and the second coil portion. The first coil portion, the second coil portion and the first connection portion are defined by a continuous length of winding wire.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, with each coil portion extending around a different one of the plurality of teeth. The stator assembly further includes a plurality of connection portions each extending between two adjacent ones of the plurality of coil portions. A first set of consecutive ones of the plurality of coil portions is defined by a first continuous length of winding wire having two wire ends. Second and third sets of consecutive ones of the plurality of coil portions are each defined by respective continuous lengths of winding wire each having two ends.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, and including a first coil portion extending around a first one of the plurality of teeth and a second coil portion extending around a second one of the plurality of teeth. The stator assembly further includes a plurality of connection portions including a first connection portion extending between the first coil portion and the second coil portion and electrically coupling the first coil portion and the second coil portion. The first coil portion, the second coil portion and the first connection portion are defined by a continuous length of winding wire.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, and including a first coil portion extending around a first one of the plurality of teeth and a second coil portion extending around a second one of the plurality of teeth. The stator assembly further includes a plurality of connection portions including a first connection portion extending between the first coil portion and the second coil portion and electrically coupling the first coil portion and the second coil portion. The first coil portion, the second coil portion and the first connection portion are defined by a continuous length of winding wire.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, with each coil portion extending around a different one of the plurality of teeth. The stator assembly further includes a plurality of connection portions each extending between two adjacent ones of the plurality of coil portions. A first set of consecutive ones of the plurality of coil portions is defined by a first continuous length of winding wire having two wire ends. Second and third sets of consecutive ones of the plurality of coil portions are each defined by respective continuous lengths of winding wire each having two ends.

Abstract: According to some aspects of the present disclosure, example stator assemblies for three phase dynamoelectric machines and related winding methods are disclosed. An example stator assembly generally includes a non-segmented stator core including a stator yoke and a plurality of teeth. The stator assembly also includes a plurality of coil portions electrically coupled in a delta winding pattern, and including a first coil portion extending around a first one of the plurality of teeth and a second coil portion extending around a second one of the plurality of teeth. The stator assembly further includes a plurality of connection portions including a first connection portion extending between the first coil portion and the second coil portion and electrically coupling the first coil portion and the second coil portion. The first coil portion, the second coil portion and the first connection portion are defined by a continuous length of winding wire.

Abstract: This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils and, optionally, a tau therapeutic or an inhibitor of amyloid beta production or aggregation.

Abstract: The present invention relates to antibodies that bind amyloid ?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention are selective for ADDLs, can penetrate the brain, and are useful in methods of detecting ADDLs and diagnosing Alzheimer's disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with ADDLs.

Abstract: This invention is a selective A? oligomer kit and immunoassay method capable of reliably and sensitively detecting A? oligomers in a biological sample of a patient. In one embodiment the inventive assay uses a pair of anti-A? oligomer antibodies, as capture and detection antibodies, to detect and quantify A? oligomers. The method can be used to differentiate Alzheimer's disease (AD) patients from non-AD patients and/or to stratify AD patients according to the severity of their disease.

Abstract: This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils, wherein the antibody is in combination with a tau therapeutic or an inhibitor of amyloid beta production or aggregation.

Abstract: This invention is a selective A? oligomer kit and immunoassay method capable of reliably and sensitively detecting A? oligomers in a biological sample of a patient. In one embodiment the inventive assay uses a pair of anti-A? oligomer antibodies, as capture and detection antibodies, to detect and quantify A? oligomers. The method can be used to differentiate Alzheimer's disease (AD) patients from non-AD patients and/or to stratify AD patients according to the severity of their disease.

Abstract: This invention is a selective A? oligomer kit and immunoassay method capable of reliably and sensitively detecting A? oligomers in a biological sample of a patient. In one embodiment the inventive assay uses a pair of anti-A? oligomer antibodies, as capture and detection antibodies, to detect and quantify A? oligomers. The method can be used to differentiate Alzheimer's disease (AD) patients from non-AD patients and/or to stratify AD patients according to the severity of their disease.

Abstract: The present invention relates to antibodies that bind amyloid ?-derived diffusible ligands, also known as ADDLs. The antibodies of the invention are selective for ADDLs, can penetrate the brain, and are useful in methods of detecting ADDLs and diagnosing Alzheimer's disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with ADDLs.

Abstract: Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.

Abstract: Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.

Abstract: Disclosed are antibodies that bind amyloid beta-derived diffusible ligands, also known as ADDLs. The antibodies are selective for ADDLs, can penetrate the brain, and are useful in methods of detecting ADDLs and diagnosing Alzheimer's disease. The antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with ADDLs.

Abstract: Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.

Abstract: Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure.