Abstract: The provided herein are methods and compositions for eliciting an immune response to an antigen, such as cancer and microbial antigens.

Abstract: Method for determining parameter of a passive impedance adapter applicable to VSC-HVDC, including: S1. obtaining VSC-HVDC impedance and VSC-HVDC impedance curve X(f) based on VSC-HVDC impedance; S2. estimating upper limit value of the main capacitor in the passive impedance adapter; S3. calculating adapter parameter curve Xadapter(f); S4. determining value of the main capacitor and varying value of the main resistor until min[X(f)?Xadapter(f)] is maximized; determining whether min[X(f)?Xadapter(f)]>k holds; S5. If min[X(f)?Xadapter(f)]>k does not hold, increasing the value of the main capacitor and performing steps S2-S4 until min[X(f)?Xadapter(f)]>k holds when the value of the main capacitor is within the range of the value of the main capacitor, storing the parameters in an available parameter set; S6. reducing the value of the main capacitor, and storing the parameters when min[X(f)?Xadapter(f)]>k holds in the available parameter set; S7.

Abstract: Process for obtaining a milk fraction enriched in immunoglobulins, preferably enriched in IgA and IgM, comprising the steps of (a) subjecting skimmed milk to microfiltration, resulting in an MF retentate rich in micellar casein and an MF permeate rich in whey proteins, (b) subjecting the MF retentate to a casein precipitation or cheese-making process, thereby creating a casein-rich fraction and a whey fraction, (c) subjecting the whey fraction obtained in step b) to microfiltration and/or anion exchange chromatography, thereby obtaining a milk fraction enriched in immunoglobulins.

Abstract: An interdental brush with a replaceable brush body with a core and a manufacturing method thereof are provided, and relate to the technical field of tooth cleaning tools. The interdental brush includes a handle, a screw cap, a fixing block and a brush body. One end of the handle is provided with an external thread, an interior of the screw cap is provided with an internal thread mating with the external thread of the one end of the handle. One end of the fixing block abuts against the handle, and an other end extends out of the screw cap. The brush body includes a core and bristles, the core is twisted by an amorphous alloy wire, one end of the core is clamped in the fixing block, and a periphery of an other end is connected to the bristles.

Abstract: An organic light-emitting diode display device is provided by the present application, including an anode layer, a cathode layer, and a light-emitting layer disposed between the anode layer and the cathode layer, wherein the light-emitting layer includes a first light-emitting layer and a second light-emitting layer stacked. The first light-emitting layer includes a first color light-emitting part, a second color light-emitting part, and a third color light-emitting part arranged in a same layer. The second light-emitting layer is configured to emit light of a first color, and the second light-emitting layer is disposed at a side of the first light-emitting layer and covers the first light-emitting layer.

Abstract: The present disclosure provides a parameter design method for a series passive impedance adapter applicable to a VSC-HVDC transmission system, to resolve the technical problem that high-frequency resonance may occur when impedance of a VSC-HVDC transmission system is mismatched with that of a sending-end or receiving-end grid. A parameter design goal of the present disclosure is that reactive power consumed by a series passive impedance adapter is not more than A times rated power of a converter, and a loss of the series passive impedance adapter in a fundamental wave is B times the rated power of the converter. The parameter design method for a series passive impedance adapter applicable to a VSC-HVDC transmission system in the present disclosure can realize a positive impedance characteristic within a concerned frequency band and completely eliminate a risk of harmonic resonance.

Abstract: The disclosed systems, structures, and methods are directed to optimizing address calculations in a computer. This is achieved in a compiler that identifies an address calculation in code that is being compiled and transforms the code by splitting the address calculation into a first portion in which an offset is determined and a second portion, in which the offset is combined with a base pointer to generate an address. The address and the base pointer have a first bit-length, and the offset has a second bit-length shorter than the first bit-length. The offset is determined using an operation performed at the second bit-length. In some implementations the first bit-length is 64 bits and the second bit-length is 32 bits.

Abstract: This application discloses a multi-sound area-based speech detection method and related apparatus, and a storage medium, which is applied to the field of artificial intelligence. The method includes: obtaining sound area information corresponding to N sound areas including multiple users speaking simultaneously; generating a control signal corresponding to each target detection sound area according to user information corresponding to the target detection sound area; processing multi-user speech input signals by using the control signals, to obtain a speech output signal corresponding to each target detection sound area; generating a speech detection result of the target detection sound area according to the speech output signal corresponding to the target detection sound area; and selecting, among the multiple users, a main speaker based on the user information, the speech output signals and speech detection results of multiple users in the N sound areas.

Abstract: This application discloses a method for positioning a target audio signal by a computer device. The method includes: performing echo cancellation on the audio signals collected in a plurality of directions in a space, the audio signals comprising a target-audio direct signal; obtaining weights of a plurality of time-frequency points in the echo-canceled audio signals, a weight of each time-frequency point indicating a relative proportion of the target-audio direct signal in the echo-canceled audio signals at the time-frequency point; obtaining a weighted audio signal energy distribution of the audio signals in the plurality of directions by using the weights of the plurality of time-frequency points in the echo-canceled audio signals; and obtaining a sound source azimuth corresponding to the target-audio direct signal in the audio signals by using the weighted audio signal energy distribution of the audio signals in the plurality of directions.

Abstract: The present invention relates to the field of medical technology, in particular to a composition for treating cancer and use and medicament thereof. The composition comprises an SGLT1 inhibitor and a VEGFR2 inhibitor. The present invention finds that SGLT1 interacts with VEGFR2 to promote the development and progression of tumors; the present invention also finds that a composition of a VEGFR2 targeting inhibitor and an SGLT1 inhibitor has a synergistic anti-tumor effect, and the composition of the VEGFR2 targeting inhibitor and the SGLT1 targeting inhibitor can be used in cancer treatment.

Abstract: The present disclosure provides a parameter design method for a series passive impedance adapter applicable to a VSC-HVDC transmission system, to resolve the technical problem that high-frequency resonance may occur when impedance of a VSC-HVDC transmission system is mismatched with that of a sending-end or receiving-end grid. A parameter design goal of the present disclosure is that reactive power consumed by a series passive impedance adapter is not more than A times rated power of a converter, and a loss of the series passive impedance adapter in a fundamental wave is B times the rated power of the converter. The parameter design method for a series passive impedance adapter applicable to a VSC-HVDC transmission system in the present disclosure can realize a positive impedance characteristic within a concerned frequency band and completely eliminate a risk of harmonic resonance.

Abstract: A welcoming slide rail, mounted at the bottom of a seat, the welcoming slide rail including: a slide rail assembly, including a left slide rail and a right slide rail, the left slide rail including a left upper rail and a left lower rail, the right slide rail including a right upper rail and a right lower rail, the left upper rail and the left lower rail being in sliding connection by a left motor, and the right upper rail and the right lower rail being in sliding connection by a right motor; and a rotating mechanism, including a wall plate, first, second and third main rotation points, and first and second auxiliary supporting points, the wall plate being fixedly connected to the bottom of the seat.

Abstract: Process for producing a whey protein-containing product enriched in immunoglobulins, said process comprising the steps of: (i) cross-flow filtration of casein-reduced milk using a membrane with a molecular weight cut-off (MWCO) of 500-1000 kDa, preferably 500-800 kDa, or a pore size of 50-100 nm, preferably 50-80 nm, thereby obtaining a permeate enriched in lactose, salts, ?-lactalbumin and ?-lactoglobulin, and an UF retentate, and (ii) subjecting said UF retentate to mixed mode chromatography, wherein immunoglobulins adhere to a resin and are subsequently eluted to form said whey protein-containing product enriched in immunoglobulins.

Abstract: Provided are a nanocomposite dielectric film material for energy storage prepared by vertical self-assembly of lead zirconate titanate (PZT) and magnesium oxide (MgO), and a preparation method thereof. The method includes: 1, preparing a PZT powder; 2, mixing the PZT powder with an MgO powder to obtain a uniformly mixed PM composite powder; and mixing the PM composite powder with a binder, and subjecting a resulting mixture to tableting and cold isostatic pressing to obtain a PM composite target blank; 3, sintering the PM composite target blank at a temperature of not higher than 900° C. to obtain a PM composite target; and 4, subjecting the PM composite target to pulsed laser deposition to form an epitaxial vertical self-assembly composite dielectric film; and subjecting the epitaxial vertical self-assembly composite dielectric film to annealing to obtain the film material.

Abstract: An electronic device obtains audio signals collected by different microphones in a microphone array. The device filters the audio signals using a first filter to obtain a first target beam. The first filter is configured to suppress an interference speech in the audio signals and enhance a target speech in the audio signals. The device filters the audio signals using a second filter to obtain a first interference beam. The second filter is configured to suppress the target speech and enhance the interference speech. The device a second interference beam of the first interference beam using a third filter. The device determines a difference between the first target beam and the second interference beam as a first audio processing output. The device adaptively updates at least one of the second filter and the third filter, and updates the first filter according to the updated second filter and/or third filter.

Abstract: Embodiments of this application disclose method and apparatus for positioning a target audio signal by an audio interaction device, and an audio interaction device The method includes: obtaining audio signals in a plurality of directions in a space, and performing echo cancellation on the audio signal, the audio signal including a target-audio direct signal; obtaining weights of a plurality of time-frequency points in the audio signals, a weight of each time-frequency point indicating, at the time-frequency point, a relative proportion of the target-audio direct signal in the audio signals; weighting time-frequency components of the audio signal at the plurality of time-frequency points separately for each of the plurality of directions by using the weights of the plurality of time-frequency points, to obtain a weighted audio signal energy distribution; and obtaining a sound source azimuth corresponding to the target-audio direct signal in the audio signals accordingly.

Abstract: The use of a negative regulator AtRTP5 for increasing the plant resistance to Phytophthora is disclosed. The AtRTP5 gene negatively regulates the plant resistance to Phytophthora by interfering with a plant hormone immune signaling pathway. The AtRTP5 gene has a nucleotide sequence shown as SEQ ID NO: 1 or a homologous sequence having more than 50% homology with the sequence. The use of a protein encoded by a negative regulator AtRTP5 for increasing the plant resistance to Phytophthora is also disclosed. The plant resistance to Phytophthora is enhanced by reducing the expression of the protein encoded by the AtRTP5 gene with genetic engineering. The protein has an amino acid sequence shown as SEQ ID NO: 2 or a homologous sequence having more than 50% homology with the sequence.

Abstract: An organic light-emitting diode display device is provided, including an anode layer, a cathode layer, a first light-emitting layer, and a second light-emitting layer disposed between the anode layer and the cathode layer, wherein the first light-emitting layer comprises a first light-emitting part, a second light-emitting part, and a third light-emitting part arranged side-by-side, the second light-emitting layer is configured to emit light of a same color as light emitted from the first light-emitting part, and the organic light-emitting diode display device further includes a charge generating layer disposed between the second light-emitting layer and the first light-emitting part.

Abstract: An organic light emitting diode device and a display panel are provided. The display panel includes the organic light emitting diode device. The organic light emitting diode device includes an emitting material layer. The emitting material layer includes a first common blue-light light-emitting layer, a red-green-blue light emitting layer, and a second common blue-light light-emitting layer.

Abstract: An electrochemical device includes a positive electrode, the positive electrode including a positive electrode current collector, a protective coating disposed on a surface of one side of the positive electrode current collector close to a tab portion, and a positive electrode active material layer disposed on a surface of at least one side of the positive electrode current collector. The protective coating includes a first active material, and the positive electrode active material layer includes a second active material. According to embodiments of this application, by disposing the protective coating on the positive electrode current collector, lithium plating at the negative electrode of the electrochemical device is alleviated while ensuring the safety performance of the electrochemical device.