Abstract: Provided is a use of methylated locus in Sonic Hedgehog subgroup medulloblastoma, which relates to the technical field of tumor classification and detection. Specifically, the present disclosure provides a use of a reagent for detecting a methylation level of at least one genetic locus selected from ROBO4, OTX2OS1, AHRR, DKK4, or PART1 in a biological sample in the preparation of a diagnostic reagent or a diagnostic kit for Sonic Hedgehog subgroup medulloblastoma. Based on analysis and comparison of data from a large number of Sonic Hedgehog subgroup medulloblastoma samples and other medulloblastoma subgroups samples the methylation level of a genetic locus in the above genes can be used as a referenced indicator for the diagnosis of Sonic Hedgehog subgroup medulloblastoma. Therefore, only a few methylated loci are targeted and detected, and MB SHE can be classified and identified, thereby reducing diagnostic difficulty and cost of Sonic Hedgehog subgroup medulloblastoma.

Abstract: The present invention discloses a method for producing a nutritional microbial solids product while simultaneously producing clean water for multiples uses. The microbial solids product represents a form of single cell protein (SCP) that finds application most typically in formulated animal feeds, but may also be used in food, fertilizer, or soil amendment products. The treated water product can be used directly or polished further for subsequent industrial or agricultural use, including aquaculture and irrigation. The process described utilizes low-value by-products of industrial production for biochemical conversion into SCP. The by-products most suitable to this approach have high organic content that otherwise makes them difficult to dispose of responsibly via traditional methods such as biological wastewater treatment.

Abstract: A method for evaluating accuracy in positioning a receiver point, which is associated with at least one shot point, and for which a derived position data is obtained, wherein a pair of the receiver point and a respective shot point is associated with a characteristic parameter which includes an offset, a velocity of first arrival wave and a first arrival time, the method comprising: step S10, constructing a residual vector associated with the receiver point and the respective shot point based on the characteristic parameter; step S12, determining a characterization parameter of the derived position data based on the residual vector; and step S14, evaluating accuracy of the derived position data based on the characterization parameter. An apparatus for evaluating accuracy in positioning a receiver point is also provided.

Abstract: The present invention relates to a process for preparing a rodlike magnetic ferroferric oxide (Fe3O4) material and use thereof. The preparation includes the following steps: step 1: magnetic Fe3O4 nanoparticle preparation; and step 2: self-assembly of magnetic Fe3O4@SiO2 nanoparticles into a rodlike magnetic material. When in use, the rodlike magnetic Fe3O4 material prepared by the process according to claim 1 is used in micro- and nano-motors, which can implement rotation and deflection in an external magnetic field. The present invention provides a process for preparing a rodlike magnetic Fe3O4 material. The rodlike magnetic ferroferric oxide material prepared by the process is suitable for mass production on an industrial scale, featuring identifiable direction of the magnetic moment, strong magnetism, good magnetic response, simple process, and low cost.

Abstract: The present invention relates to a medical wristband with invisible information and a method for manufacturing the same. The conventional developed dyes or inks in the prior art can store information which, however, is visible. In the present invention, polystyrene (PS) microspheres are prepared by micro-emulsification: PS particles are dissolved in a toluene solution and a fluorescent dye is added to obtain a fluorescent solution; an SDS solution is added in and mixed with the fluorescent solution to obtain a system to be ultrasonically emulsified; and the system is ultrasonically emulsified and the toluene is completely volatilized. The ink can be used directly as an invisible ink. The information is written, as two-dimensional codes and by the ink, on a piece of non-fluorescent paper, and plastic-packaged onto a wristband of a patient. Information about a patient can be successfully scanned in the ease of UV on.

Abstract: The present invention belongs to the technical field of material fabrication, and particularly relates to an ultra-sensitive glucose sensor based on a graphene and carbon fiber substrate and a fabrication method thereof. The method includes fabricating a carbon fiber cloth with vertical graphene growth on a surface thereof, performing pretreatment to make the carbon fiber cloth hydrophilic, directly soaking the carbon fiber cloth in a PBS solution of glucose oxidase with the pH of 7.4, and then taking out and drying the carbon fiber cloth at room temperature to obtain a glucose sensor. According to the present invention, the lower limit of glucose detection reaches about 0.1 mM, and the glucose sensor also has multistage corresponding characteristics, so that different detection coefficients and capabilities can be achieved in different glucose concentration ranges. The application range and precision of the glucose sensor are greatly improved.

Abstract: A method for producing aerobic-type single cell protein using the autolysis process, comprising the following steps: precipitation and concentration, centrifugal dewatering, drying, sterilization, smashing and packaging. The materials with moisture content of 78%˜85% after centrifugal dewatering are dried after the autolysis. The present invention and its products employ the autolysis process. During the autolysis, macromolecular nutrients and cell walls are decomposed by autolytic enzymes, to produce high content of free amino acids, free nucleotides; besides, cell wall polysaccharides are decomposed and the cells produce permeability to ensure an active material can flow out of the cell which can be directly absorbed by animals.

Abstract: Methods to produce microbial biomass are provided. The methods involve the inoculation of a liquid growth medium including a controlled substrate with a microbial inoculum and incubation under conditions that are suitable for the production of biomass. The biomass and/or the liquid growth medium may be used to produce valuable products including food and feed products.

Abstract: Embodiments of the present disclosure disclose a display apparatus and a method of manufacturing the display apparatus. A display panel includes a liquid crystal cell, a lower polarization filter, and a layer of which at least a pair of edges protrude beyond the liquid crystal cell. Adhesive layers are disposed on side surfaces of the display module. In any one of the side surfaces of the display module, the adhesive layer is adhered to side surfaces of the backlight module, of the lower polarization filter, and of the liquid crystal cell, and a surface, facing towards the backlight module, of the edge of the layer protruding beyond the liquid crystal cell, and has a thickness in a direction perpendicular to the side surface of the liquid crystal cell to which the adhesive layer is adhered, and the thickness is less than or equal to a selected thickness.

Abstract: An affinity ligand peptide library of IgG constructed on the basis of Protein A affinity model and the application of a design method thereof. According to the Molecular Mechanics—Poisson-Boltzmann surface area (MM/PBSA) method and on the basis of the known human IgG-Protein A complex structure, the hot spots of Protein A that have high affinity for human IgG are obtained analytically, and a Protein A simplified affinity model is built thereof. An affinity peptide library of IgG is constructed including heptapeptide and octapeptide structural modes. On the basis of the peptide structural modes, the types of inserted amino acids that ‘X’ residues represent are further identified using amino acid location method. Then, molecular docking and molecular dynamics simulation methods are used to screen the candidate peptides successively. Finally, the affinity peptide ligands that can effectively purify IgG are identified using affinity chromatography.

Abstract: Embodiments of the present disclosure disclose a display apparatus and a method of manufacturing the display apparatus. A display panel includes a liquid crystal cell, a lower polarization filter, and a layer of which at least a pair of edges protrude beyond the liquid crystal cell. Adhesive layers are disposed on side surfaces of the display module. In any one of the side surfaces of the display module, the adhesive layer is adhered to side surfaces of the backlight module, of the lower polarization filter, and of the liquid crystal cell, and a surface, facing towards the backlight module, of the edge of the layer protruding beyond the liquid crystal cell, and has a thickness in a direction perpendicular to the side surface of the liquid crystal cell to which the adhesive layer is adhered, and the thickness is less than or equal to a selected thickness.

Abstract: An efficient combined advanced treatment method of electroplating wastewater is disclosed, which belongs to the technical field of electroplating wastewater treatment. The method includes: after pretreatments including cyanide breaking, dechromization and coagulating sedimentation, introducing the electroplating wastewater to a contact oxidation tank for biochemical treatment, and settling the effluent from the contact oxidation tank down in an inclined pipe of a secondary sedimentation tank to realize the separation of the sludge from water; charging the effluent to a coagulating sedimentation tank, and undergoing coagulating sedimentation with the aid of a flocculant and a coagulant aid added; feeding the effluent, as an influent, to a resin adsorption tank for adsorption with a magnetic resin; and after passing through a filter, flowing the effluent after adsorption to a fixed bed resin adsorption unit, so as to realize the discharge up to standard and recycle of the effluent.

Abstract: A method for producing aerobic-type single cell protein using the autolysis process, comprising the following steps: precipitation and concentration, centrifugal dewatering, drying, sterilization, smashing and packaging. The materials with moisture content of 78%˜85% after centrifugal dewatering are dried after the autolysis. The present invention and its products employ the autolysis process. During the autolysis, macromolecular nutrients and cell walls are decomposed by autolytic enzymes, to produce high content of free amino acids, free nucleotides; besides, cell wall polysaccharides are decomposed and the cells produce permeability to ensure an active material can flow out of the cell which can be directly absorbed by animals.

Abstract: An affinity ligand peptide library of IgG constructed on the basis of Protein A affinity model and the application of a design method thereof According to the Molecular Mechanics—Poisson-Boltzmann surface area (MM/PBSA) method and on the basis of the known human IgG-Protein A complex structure, the hot spots of Protein A that have high affinity for human IgG are obtained analytically, and a Protein A simplified affinity model is built thereof. An affinity peptide library of IgG is constructed including heptapeptide and octapeptide structural modes. On the basis of the peptide structural modes, the types of inserted amino acids that ‘X’ residues represent are further identified using amino acid location method. Then, molecular docking and molecular dynamics simulation methods are used to screen the candidate peptides successively. Finally, the affinity peptide ligands that can effectively purify IgG are identified using affinity chromatography.

Abstract: An efficient combined advanced treatment method of electroplating wastewater is disclosed, which belongs to the technical field of electroplating wastewater treatment. The method includes: after pretreatments including cyanide breaking, dechromisation and coagulating sedimentation, introducing the electroplating wastewater to a contact oxidation tank for biochemical treatment, and settling the effluent from the contact oxidation tank down in an inclined pipe of a secondary sedimentation tank to realize the separation of the sludge from water; charging the effluent to a coagulating sedimentation tank, and undergoing coagulating sedimentation with the aid of a flocculant and a coagulant aid added; feeding the effluent, as an influent, to a resin adsorption tank for adsorption with a magnetic resin; and after passing through a filter, flowing the effluent after adsorption to a fixed bed resin adsorption unit, so as to realize the discharge up to standard and recycle of the effluent.

Abstract: Systems and methods for monitoring and improving software development quality are described herein. In accordance with one aspect of the present disclosure, an occurrence of a monitoring task related to source code is monitored. The source code is compiled and tested to produce a test result. The test result is analyzed. The test result analysis includes quality analysis to assess the quality of the source code.

Abstract: A method of ultrasonic brazing metal matrix composite, which forms a reinforced composite bond without filling welding wire with reinforcement or adding alloy element to generate ceramic phase, includes the steps of setting a filler metal; introducing ultrasonic vibration to braze in air; dissolving the base materials, and introducing ultrasonic wave again. The method performs the aluminum brazing at low temperature. The periodic time of brazing is shorter and the cost is lower than the conventional brazing methods. The strength, service temperature and dimensional stability of the joint are close to the base article.

Abstract: A method of ultrasonic brazing metal matrix composite, which forms a reinforced composite bond without filling welding wire with reinforcement or adding alloy element to generate ceramic phase, includes the steps of setting a filler metal; introducing ultrasonic vibration to braze in air; dissolving the base materials, and introducing ultrasonic wave again. The method performs the aluminum brazing at low temperature. The periodic time of brazing is shorter and the cost is lower than the conventional brazing methods. The strength, service temperature and dimensional stability of the joint are close to the base article.

Abstract: The present invention comprises an apparatus and a method for measuring the first arrival time of seismic waves from detonation in seismic explorations, comprising a or several detectors for measuring seismic waves and converting them into electrical signals and a signal processing means for calculating an average energy of the electrical signals to determine the first arrival time of seismic waves and using a smooth filtering method to compute accurately the first arrival time backwards from the first maximum valve in the average energy curve.

Abstract: The present invention provides a apparatus and a method used for measuring the detonation time and the first arrival time of seismic waved caused in the seismic exploration field, wherein said apparatus includes a signal measuring means used for measuring current and voltage of the detonation circuit, a test signal generating means used for adding to the detonation circuit a &ohgr;-frequency sine wave test signal in order to smooth filter out noise and interference to enhance accuracy of measurement and a signal-processing means used for detecting and measuring current and voltage with same frequency as the &ohgr;-frequency test signal from current and voltage measured by the signal measuring means, and thus computing the curve of impedance changes and, in some extent to eliminate noise and interference and to determine accurately the detonation time TB.