Patents by Inventor Weixang Dai

Weixang Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of proliferation and fibrotic response of activated corneal stromal cells
    Patent number: 8815946
    Abstract: Provided herein are methods of preventing a fibrotic response and/or scarring in a wound, comprising administering to a subject a composition comprising an amount of an amide or ester of an alpha-ketoalkanoic acid effective to inhibit a proliferative and/or fibrotic response in the wound. In one instance, the wound is to a subject's cornea, such as a wound resulting from refractive surgery. In one embodiment, the amide or ester of an alpha-ketoalkanoic acid is ethyl pyruvate.
    Type: Grant
    Filed: January 26, 2009
    Date of Patent: August 26, 2014
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Weixang Dai, James L. Funderburgh, Joel S. Schuman, Nirmala SundarRaj
  • Inhibition of proliferation and fibrotic response of activated corneal stromal cells
    Publication number: 20090239947
    Abstract: Provided herein are methods of preventing a fibrotic response and/or scarring in a wound, comprising administering to a subject a composition comprising an amount of an amide or ester of an alpha-ketoalkanoic acid effective to inhibit a proliferative and/or fibrotic response in the wound. In one instance, the wound is to a subject's cornea, such as a wound resulting from refractive surgery. In one embodiment, the amide or ester of an alpha-ketoalkanoic acid is ethyl pyruvate.
    Type: Application
    Filed: January 26, 2009
    Publication date: September 24, 2009
    Inventors: Weixang Dai, James L. Funderburgh, Joel S. Schuman, Nirmala SundarRaj