Patents by Inventor Weixu MENG

Weixu MENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANTIBODIES AND ANTIBODY CONJUGATES FOR THE TREATMENT OF METABOLIC DISORDERS
    Publication number: 20250163168
    Abstract: Disclosed herein are novel antibodies, novel agonist peptides, and novel dual agonist peptides. Further disclosed herein are novel antibody conjugates comprising the novel antibodies, novel agonist peptides, and/or novel dual agonist peptides disclosed herein. In some embodiments, the antibodies or antibody conjugates of the invention may be used to treat metabolic diseases.
    Type: Application
    Filed: November 14, 2024
    Publication date: May 22, 2025
    Applicant: PFIZER INC.
    Inventors: James Reasoner APGAR, Robert Gregory DULLEA, Jean-Philippe FORTIN, Allison Nicole LAU, Laura LIN LOHSE, Weixu MENG, Lidia MOSYAK
  • ANTI-IL1RAP ANTIBODIES
    Publication number: 20230081443
    Abstract: Provided herein are, inter alia, antibodies capable of binding Interleukin-1 receptor accessory protein (IL1RAP). The antibodies provided herein include novel light chain and heavy chain sequences and bind IL1RAP with high efficiency and specificity. The anti-IL1RAP antibodies provided herein are, inter alia, useful for the treatment of IL1RAP-expressing cancers such as AML.
    Type: Application
    Filed: June 28, 2022
    Publication date: March 16, 2023
    Inventors: Weixu MENG, Guido MARCUCCI
  • IL1RAP ANTIBODIES
    Publication number: 20220306750
    Abstract: Provided herein are, inter alia, Interleukin-1 receptor accessory protein (IL1RAP) antibodies and fragments thereof which may form part of chimeric antigen receptors or bispsecific antibodies and are useful for treating IL1RAP-expressing cancers.
    Type: Application
    Filed: August 12, 2020
    Publication date: September 29, 2022
    Inventors: Bin Zhang, Weixu Meng, Guido Marcucci
  • Anti-IL1RAP antibodies
    Patent number: 11370842
    Abstract: Provided herein are, inter alia, antibodies capable of binding Interleukin-1 receptor accessory protein (IL1RAP). The antibodies provided herein include novel light chain and heavy chain sequences and bind IL1RAP with high efficiency and specificity. The anti-IL1RAP antibodies provided herein are, inter alia, useful for the treatment of IL1RAP-expressing cancers such as AML.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: June 28, 2022
    Assignee: CITY OF HOPE
    Inventors: Weixu Meng, Guido Marcucci
  • MODULATION OF WNT SIGNALING IN GASTROINTESTINAL DISORDERS
    Publication number: 20220195053
    Abstract: The present invention provides methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway. Also provided are methods of dosing and pharmaceutical compositions.
    Type: Application
    Filed: March 11, 2020
    Publication date: June 23, 2022
    Applicant: Surrozen Operating Inc.
    Inventors: Yang LI, Chenggang LU, Hélène BARIBAULT, Wen-Chen YEH, Liqin XIE, I-Chieh WANG, Weixu MENG
  • ANTI-IL1RAP ANTIBODIES
    Publication number: 20200247893
    Abstract: Provided herein are, inter alia, antibodies capable of binding Interleukin-1 receptor accessory protein (IL1RAP). The antibodies provided herein include novel light chain and heavy chain sequences and bind IL1RAP with high efficiency and specificity. The anti-IL1RAP antibodies provided herein are, inter alia, useful for the treatment of IL1RAP-expressing cancers such as AML.
    Type: Application
    Filed: August 1, 2018
    Publication date: August 6, 2020
    Inventors: Weixu MENG, Guido MARCUCCI