Patents by Inventor Weixue Tian

Weixue Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11608334
    Abstract: The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for the treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 21, 2023
    Assignee: THE NATIONAL INSTITUTES OF PHARMACEUTICAL R&D CO., LTD.
    Inventors: Huijun Yin, Xu Yan, Libin Zong, Weixue Tian, Li Zheng, Haoshuai Dou, Yan Yang
  • Publication number: 20220041616
    Abstract: The present invention relates to a spiro compound and medical uses thereof. Specifically, the present invention relates to a spiro compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the same, and is used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor and is used for treating diseases associated with ACC activity. Each substituent in the general formula (I) is as defined in description.
    Type: Application
    Filed: November 20, 2019
    Publication date: February 10, 2022
    Inventors: Huijun YIN, Xu YAN, Junge WEN, Weixue TIAN, Qiyong MOU, Ning FU, Jingqian JIANG, Yao WU, Guosheng WU, Xueying FENG, Su QIAN
  • Publication number: 20200062749
    Abstract: The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for the treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description.
    Type: Application
    Filed: December 26, 2017
    Publication date: February 27, 2020
    Applicant: The National Institutes of Pharmaceutical Research and Development (NIP)
    Inventors: Huijun YIN, Xu YAN, Libin ZONG, Weixue TIAN, Li ZHENG, Haoshuai DOU, Yan YANG
  • Patent number: 10518829
    Abstract: A track pin may comprise a body that includes a generally cylindrical configuration defining an axis of rotation, a circumferential direction and a radial direction, the body defining a first end, a second end and a peripheral surface extending from the first end to the second end. The peripheral surface may include a first lobed portion spaced axially away from the first end and the second end and including a series of convex arcuate segments and concave arcuate segments joined to each other tangentially, forming an undulating surface.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: December 31, 2019
    Assignee: Caterpillar Inc.
    Inventors: Timothy Allen McKinley, Zhiyong Hu, Weixue Tian, William Henry Baar, III
  • Publication number: 20180370583
    Abstract: A track pin may comprise a body that includes a generally cylindrical configuration defining an axis of rotation, a circumferential direction and a radial direction, the body defining a first end, a second end and a peripheral surface extending from the first end to the second end. The peripheral surface may include a first lobed portion spaced axially away from the first end and the second end and including a series of convex arcuate segments and concave arcuate segments joined to each other tangentially, forming an undulating surface.
    Type: Application
    Filed: June 26, 2017
    Publication date: December 27, 2018
    Applicant: Caterpillar Inc.
    Inventors: Timothy Allen McKinley, Zhiyong Hu, Weixue Tian, William Henry Baar, III
  • Patent number: 9970523
    Abstract: A torque converter includes a housing, and an impeller shell disposed within the housing. The impeller shell has a back wall, and a plurality of fins radially arranged and extending outwardly from the back wall. The torque converter further includes a backing hub rigidly coupled to the back wall of the impeller shell. The backing hub has a barrier element extending therefrom. A free end of the barrier element is disposed proximal to the housing to restrict a flow of fluid therebetween.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: May 15, 2018
    Assignee: Caterpillar Inc.
    Inventors: Valerie Annette Ross, Xuekui Lan, Jim Wu, Qinyang Rao, Timothy M. Waters, Weixue Tian
  • Publication number: 20170059022
    Abstract: A torque converter includes a housing, and an impeller shell disposed within the housing. The impeller shell has a back wall, and a plurality of fins radially arranged and extending outwardly from the back wall. The torque converter further includes a backing hub rigidly coupled to the back wall of the impeller shell. The backing hub has a barrier element extending therefrom. A free end of the barrier element is disposed proximal to the housing to restrict a flow of fluid therebetween.
    Type: Application
    Filed: August 28, 2015
    Publication date: March 2, 2017
    Applicant: Caterpillar Inc.
    Inventors: Valerie Annette Ross, Xuekui Lan, Jim Wu, Qinyang Rao, Timothy M. Waters, Weixue Tian
  • Patent number: 8960227
    Abstract: A tank for a hydraulic fluid has a housing with opposed end walls and side walls defining an interior chamber. A primary baffle is disposed inside the housing and divides the interior chamber into an inlet chamber and an outlet chamber, with a primary gap between the primary baffle and the housing fluidly communicating between the inlet chamber and the outlet chamber. The primary baffle further defines a contact surface facing the inlet chamber and has first and second weirs which extend into the inlet chamber. A first fluid inlet fluidly communicates with the inlet chamber and is oriented along a first inlet axis that intersects the contact surface, while a fluid outlet communicates with the outlet chamber. The tank produces an interior flow that mixes and deaerates the fluid as it travels from the first fluid inlet to the fluid outlet.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: February 24, 2015
    Assignee: Caterpillar SARL
    Inventors: Sage Frederick Smith, Brian Franklin Taggart, Xuekui Lan, Weixue Tian
  • Publication number: 20130240069
    Abstract: A tank for a hydraulic fluid has a housing with opposed end walls and side walls defining an interior chamber. A primary baffle is disposed inside the housing and divides the interior chamber into an inlet chamber and an outlet chamber, with a primary gap between the primary baffle and the housing fluidly communicating between the inlet chamber and the outlet chamber. The primary baffle further defines a contact surface facing the inlet chamber and has first and second weirs which extend into the inlet chamber. A first fluid inlet fluidly communicates with the inlet chamber and is oriented along a first inlet axis that intersects the contact surface, while a fluid outlet communicates with the outlet chamber. The tank produces an interior flow that mixes and deaerates the fluid as it travels from the first fluid inlet to the fluid outlet.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 19, 2013
    Applicant: CATERPILLAR, INC.
    Inventors: Sage Frederick Smith, Brian Franklin Taggart, Xuekui Lan, Weixue Tian