Abstract: Embodiments of present disclosure relate to a system for lidding a container and a method for lidding a container. The system for lidding a container includes a conveying device configured to convey a container, the container having a non-circular opening. The system includes a lid retaining assembly configured to retain a lid in a fixed orientation, and a container adjustment device configured to adjust a posture of the container to be lidded on the conveying device, so that the opening of the container is aligned with the lid.

Abstract: A method including contacting a target molecule in a sample with a probe, the probe containing a target molecule binding domain capable of specifically binding to the target molecule and at least one reaction blocking modification, carrying out a first processing on a first region of the sample to cause the probe in the first region to be attached to a first tag sequence, carrying out a second processing on a second region that is different from the first region in the sample to cause the probe in the second region to be attached to a second tag sequence, the second tag sequence being different from the first tag sequence, and determining a composition of the probe attached to the first tag sequence and the probe attached to the second tag sequence.

Abstract: A method for analyzing a target molecule from a sample, including contacting at least one target molecule in the sample with at least one probe, where the at least one probe contains a target molecule binding domain, and the target molecule binding domain is capable of specifically recognizing the at least one target molecule in the sample, attaching the at least one probe to a sample-specific barcode to obtain a barcoded probe, determining a composition of the barcoded probe, and determining a presence and/or content of the at least one target molecule in the sample from the composition of the barcoded probe.

Abstract: A method for analyzing target nucleic acid from a cell, including: 1) providing a discrete partition: target nucleic acid derived from a single cell and added with an oligonucleotide adaptor sequence, and a solid support with at least one oligonucleotide tag attached, wherein each oligonucleotide tag includes a first and second strand, the first strand includes a barcode sequence and a hybridization sequence located at the 3?-end of the barcode sequence, the second strand includes a first portion, complementary to the hybridization sequence of the first strand, and a second portion, complementary to the oligonucleotide adaptor sequence attached to the target nucleic acid, and the first and second strand form a partial double-strand, or the second strand and target nucleic acid attached form a partial double-strand; and (2) in the discrete partition, the oligonucleotide tag is linked to the target nucleic acid attached, thereby producing barcoded target nucleic acid.