Abstract: The present disclosure provides a cyclic Gd (III) complex with a chemical structure shown in formula I, where a ring structure of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is used as a parent ring, lipophilic groups R? and R? in formula I are respectively introduced to a ?-position of phenylacetic acid (PAA) and a benzene ring structure, and a chiral group R in formula I is introduced to a DOTA macrocycle position. The chiral group R can increase the rigidity of a macrocyclic structure and improve the stability of the complex, and the lipophilic groups R? and R? can bind to hepatocellular organic anion transporting polypeptides (OATPs), thereby greatly improving the distribution of the cyclic Gd (III) complex as a contrast agent in the liver and gallbladder, that is, thereby providing excellent targetability.

Abstract: A tool with a driver, a structure, a motor assembly and a bumper. The driver has a plurality of bumper tabs, each of the bumper tabs having an arcuate first contact surface that is formed about a tab axis, each tab axis being generally perpendicular to a translation axis about which the driver translates. The motor assembly is coupled to the structure and configured to selectively translate the driver along the translation axis. The bumper abuts the structure and includes a plurality of bumper members. Each bumper member is located in-line with an associated one of the bumper tabs and includes an arcuate second contact surface that is formed about an axis that is generally orthogonal to the translation axis and the tab axis.

Abstract: A tool with a driver, a structure, a motor assembly and a bumper. The driver has a plurality of bumper tabs, each of the bumper tabs having an arcuate first contact surface that is formed about a tab axis, each tab axis being generally perpendicular to a translation axis about which the driver translates. The motor assembly is coupled to the structure and configured to selectively translate the driver along the translation axis. The bumper abuts the structure and includes a plurality of bumper members. Each bumper member is located in-line with an associated one of the bumper tabs and includes an arcuate second contact surface that is formed about an axis that is generally orthogonal to the translation axis and the tab axis.