Patents by Inventor Weizhou Chen

Weizhou Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted benzyl or phenyl aromatic sulfamides compounds and the use thereof
    Patent number: 6605635
    Abstract: N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)benzyl aromatic sulfonamides and N-(3,5-bis-disubstituted aminomethyl-4-hydroxy)phenyl aromatic sulfonamides compounds in accordance with the animal test, are active in the prevention and the treatment of cardiac arrhythmia. These compounds are prepared as corresponding diamines by the condensation of optionally substituted aromatic sulfochlorides with p-hydroxybenzylamine, p-aminophenol, or the like, which followed by the Mannich reaction of the resulted corresponding aromatic sulfamides with formaldehyde and secondary amines; or directly obtained by the reaction of the aromatic sulfamides with 4-amino-2,6-bis-disubstituted aminomethylphenol. Subsequently, the diamines are reacted with various acids to provide their salts.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: August 12, 2003
    Assignee: Shanghai Institute of Materia Medica Chinese Academy of Science
    Inventors: Donglu Bai, Weizhou Chen, Yunxin Bu, Yiping Wang, Yueli Dong, Aili Kang