Patents by Inventor Weizhu An
Weizhu An has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110213763Abstract: Described herein is technology for, among other things, mining pair-based data on the web. The technology involves an online pair-based data mining system as well as an offline SVM training system. By subjecting a pair-based input data to the systems, one may grow a pool of pair-based data which share characteristics of the pair-based input data in more efficient manner.Type: ApplicationFiled: May 4, 2011Publication date: September 1, 2011Applicant: MICROSOFT CORPORATIONInventors: Weizhu Chen, Long Jiang, Ming Zhou, Benyu Zhang, Zheng Chen, Jian Wang
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Publication number: 20110201627Abstract: A stable freeze-dried powder preparation of tetrodotoxin and the producing method thereof. The freeze-dried powder preparation has tetrodotoxin as the main active ingredient, and comprises solubilizer, excipient and stabilizer. The said solubilizer is citric acid. The excipient is sodium chloride, mannitol or their composite. The stabilizer is dextran, trehalose or their composite. The ratio of tetrodotoxin, excipient and stabilizer is 1:150-3000:50-500 or 50-6000. Preferably, the preparation comprises lidocaine hydrochloride as function modulator. The preparation of the present invention can be used for avoiding the dependent abstinence syndrome of drugs such as opiates and cannabis.Type: ApplicationFiled: September 17, 2009Publication date: August 18, 2011Inventors: Ruizao Yi, Hui Chen, Bihong Hong, Rongwei Xie, Weizhu Chen, Zhuan Hong, Shuzhen Xu
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Patent number: 7962507Abstract: Described herein is technology for, among other things, mining pair-based data on the web. The technology involves an online pair-based data mining system as well as an offline SVM training system. By subjecting a pair-based input data to the systems, one may grow a pool of pair-based data which share characteristics of the pair-based input data in more efficient manner.Type: GrantFiled: November 19, 2007Date of Patent: June 14, 2011Assignee: Microsoft CorporationInventors: Weizhu Chen, Long Jiang, Ming Zhou, Benyu Zhang, Zheng Chen, Jian Wang
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Patent number: 7873904Abstract: Systems and methods are described for an Internet visualization system and related user interfaces. In one implementation, the system analyzes Internet search logs to determine most popular search queries across the world at a current time. A user interface displays a keyword of each of the most popular queries in a single visual display that relates each query to a geographical location of greatest popularity. The system can also filter queries according to demographics. In one implementation the user interface provides a 3-dimensional Internet visualization that adopts an ocean or seascape theme. The ocean floor displays a map of the world, and query bubbles rise from geographical locations on the map. The size and duration of each query bubble denotes the relative popularity of a given query.Type: GrantFiled: January 10, 2008Date of Patent: January 18, 2011Assignee: Microsoft CorporationInventors: Min Wang, Weizhu Chen, Benyu Zhang, Zheng Chen, Jian Wang
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Patent number: 7870132Abstract: The claimed subject matter is directed to constructing query hierarchies in response to a query request. To construct a query hierarchy, a list of related candidate queries is generated in response to the received query request. The list of related candidate queries is generated by determining the relative coverage of information shared by the candidate queries and the query request. Relationships between the submitted query request and the candidate queries in the list are determined based upon the extent of relative coverage of information shared by the candidate queries and the query request. A query hierarchy is then constructed to reflect the determined relationships between the query request and the candidate queries.Type: GrantFiled: January 28, 2008Date of Patent: January 11, 2011Assignee: Microsoft CorporationInventors: Weizhu Chen, Benyu Zhang, Zheng Chen, Jian Wang, Dou Shen
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Publication number: 20100311955Abstract: The present invention provides a humanized anti-human CD34 antibody and the preparation method thereof. The humanized anti-human CD34 antibody retains the affinity and specificity of its original murine-derived antibody. The antibody can be conjugated with magnetic nano materials to prepare immunomagnetic beads to screen marrow hemopoietic stem cells. It can effectively reduce the incidence rate of HAMA and improve the security of clinical transplantation of hemopoietic stem cells and can be used in treatment of certain malignant hematologic diseases and solid tumors.Type: ApplicationFiled: December 3, 2008Publication date: December 9, 2010Applicant: Shanhai Guojian Bio-Tech InstituteInventors: Yajun Guo, Weizhu Qian, Sheng Hou, Bohua Li, Hao Wang, Jing Ma
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Publication number: 20100239588Abstract: The present invention discloses the functional epitope of osteopontin; the anti-osteopontin monoclonal antibody and immune conjugate raising against the functional epitope and their use for preparing anti-tumor drug. The present invention also discloses the DNA sequence encoding the monoclonal antibody, the vector and host cell containing the DNA sequence. The monoclonal antibody and immune conjugate of present invention can also be used to detect OPN. Through inhibiting OPN, the monoclonal antibody or immune conjugate of present invention can remedy or respite autoimmune diseases and protect correlative tissues, so they can be used to remedy autoimmune diseases.Type: ApplicationFiled: March 25, 2008Publication date: September 23, 2010Applicant: Shanghai National Engineering Research Center of Antibody Medicine Co.Inventors: Yajun Guo, Jianxin Dai, Hao Wang, Geng Kou, Shang Hou, Weizhu Qian, Kexing Fan
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Publication number: 20100161642Abstract: Methods and technologies providing translations of web queries based on an analysis of user behavior in click-through data. These methods and technologies generates large-scale and timely query translation pairs guided by a small set of seed word pairs from a dictionary, without relying on additional knowledge or complex models.Type: ApplicationFiled: December 23, 2008Publication date: June 24, 2010Applicant: Microsoft CorporationInventors: Zheng Chen, Weizhu Chen
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Publication number: 20100151486Abstract: Provided are functional epitopes of osteopontin (OPN), monoclonal antibodies that specifically bind to the epitopes, immunoconjugates comprising the monoclonal antibodies and use of the monoclonal antibodies or immunoconjugates for manufacturing a medicament for the treatment of tumor. Also provided are nucleotide sequences encoding the monoclonal antibodies and vectors and host cells comprising the sequences. The monoclonal antibodies or immunoconjugates can be used for detecting the OPN, blocking the promoting metastasis-signaling pathway mediated by OPN and preventing the development and metastasis of tumor, thereby inhibiting the tumor.Type: ApplicationFiled: March 25, 2008Publication date: June 17, 2010Applicant: SHANGHAI NATIONAL ENGINEERING RESEARCH CENTER OF AInventors: Yajun Guo, Jianxin Dai, Hao Wang, Geng Kou, Shang Hou, Weizhu Qian, Ling Peng
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Publication number: 20100088303Abstract: Described is a technology in which new words (including a phrase or set of Chinese characters) are mined from a query log. The new words may be added to (or otherwise supplement) an IME dictionary. A set of candidate queries may be selected from the log based upon market (e.g., the Chinese market) and/or by language. From this set, various filtering steps are performed to locate only new words that are frequently in used. For example, only frequent queries are kept for further processing, which may include filtering out queries based on length (e.g., less than two or greater than eight Chinese characters), and/or filtering out queries based on too many stop-words in the query. Processing may also include filtering out a query that is a substring of a larger query, or Vice-versa. Also described is Pinyin-based clustering and filtering, and filtering out queries already handled in the dictionary.Type: ApplicationFiled: October 3, 2008Publication date: April 8, 2010Applicant: MICROSOFT CORPORATIONInventors: Weizhu Chen, Qian Xun Li, Li Ju, Zheng Chen, Dong LI, Zhikai Fan
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Publication number: 20090193047Abstract: The claimed subject matter is directed to constructing query hierarchies in response to a query request. To construct a query hierarchy, a list of related candidate queries is generated in response to the received query request. The list of related candidate queries is generated by determining the relative coverage of information shared by the candidate queries and the query request. Relationships between the submitted query request and the candidate queries in the list are determined based upon the extent of relative coverage of information shared by the candidate queries and the query request. A query hierarchy is then constructed to reflect the determined relationships between the query request and the candidate queries.Type: ApplicationFiled: January 28, 2008Publication date: July 30, 2009Applicant: MICROSOFT CORPORATIONInventors: Weizhu Chen, Benyu Zhang, Zheng Chen, Jian Wang, Dou Shen
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Publication number: 20090132530Abstract: Described herein is technology for, among other things, mining pair-based data on the web. The technology involves an online pair-based data mining system as well as an offline SVM training system. By subjecting a pair-based input data to the systems, one may grow a pool of pair-based data which share characteristics of the pair-based input data in more efficient manner.Type: ApplicationFiled: November 19, 2007Publication date: May 21, 2009Applicant: MICROSOFT CORPORATIONInventors: Weizhu Chen, Long Jiang, Ming Zhou, Benyu Zhang, Zheng Chen, Jian Wang
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Publication number: 20080256444Abstract: Systems and methods are described for an Internet visualization system and related user interfaces. In one implementation, the system analyzes Internet search logs to determine most popular search queries across the world at a current time. A user interface displays a keyword of each of the most popular queries in a single visual display that relates each query to a geographical location of greatest popularity. The system can also filter queries according to demographics. In one implementation the user interface provides a 3-dimensional Internet visualization that adopts an ocean or seascape theme. The ocean floor displays a map of the world, and query bubbles rise from geographical locations on the map. The size and duration of each query bubble denotes the relative popularity of a given query.Type: ApplicationFiled: January 10, 2008Publication date: October 16, 2008Applicant: Microsoft CorporationInventors: Min Wang, Weizhu Chen, Benyu Zhang, Zheng Chen, Jian Wang
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Publication number: 20070243308Abstract: A stable trans fat free emulsifier composition is provided that may have other functional ingredients incorporated to form a base for a flour-based dough preparation to hold the ingredients together. A glyceride emulsifier is heated above its melting point and blended with a non-hydrogenated vegetable oil, or a quantity of glyceride emulsifier is blended with non-hydrogenated vegetable oil and the mixture then heated to a temperature above its melting point. The ratio of emulsifier to vegetable oil is selected to cause the composition, upon cooling, to form a solid plastic mass. The hardness value of the plastic mass is within a range especially applicable to bakery dough applications.Type: ApplicationFiled: April 13, 2006Publication date: October 18, 2007Inventors: Weizhu Yu, Richard Jackson
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Publication number: 20060286212Abstract: New caramel compositions suitable for use with crisp bases such as cookies and crackers are provided. The new caramel compositions are able be packaged over long periods of storage in direct contact with a crisp base comprised of a cookie or cracker without adversely affecting the texture of either the crisp base or the caramel. They comprise a cooked mixture prepared from: liquid triglyceride, monosaccharide, disaccharide, polyol, milk solids, and emulsifier. The caramel exhibits an Aw of less than 0.42. Processing entails: mixing ingredients comprising liquid triglyceride, monosaccharide, disaccharide, polyol, milk solids, and emulsifier in a heating vessel; heating the ingredients to form a uniform heated mixture while scraping the vessel during heating to prevent scorching; and increasing the heat to boil the ingredients to a temperature and for a time to achieve caramelization.Type: ApplicationFiled: June 7, 2005Publication date: December 21, 2006Inventor: Weizhu Yu
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Patent number: 6905720Abstract: A savory, smooth-textured, bakeable and shelf-stable product is prepared as a three-phase formulation, including an aqueous liquid phase, a dispersed fat phase and a solids phase, preferably containing cheese in significant proportion. The liquid phase is present in sufficient quantity to suspend and disperse the fat and solids phases. The dispersed fat must have sufficiently small droplet size raise the viscosity for this phase sufficiently to result in a creamy texture for the final product. The savory flavor ingredients are present as undissolved solids of sufficiently small particle size to provide the proper flavor release for the flavor and a texture consistent with the savory flavor. Preferred cheese products will have a lubricous, slippery, smooth mouthfeel and a flavor release that endures until the palate is essentially clean. The product can be applied to unbaked doughs prior to baking and retain their desired properties after baking.Type: GrantFiled: January 30, 2002Date of Patent: June 14, 2005Assignee: Kraft Foods Holdings, Inc.Inventors: Chii-Fen Wang, Weizhu Yu, Harry Levine, Ramanathan Santhanagopalan, Louise Slade, Zhen-Yi Yan
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Patent number: 6863911Abstract: A creamy product with a lubricious mouthfeel is bake-stable and suitable as a filler or topping for baked goods. In a preferred form, it comprises: at least 30% by weight of a discontinuous fat portion; at least 20% of a continuous aqueous liquid component for providing sweetness and stability, comprising liquid sugar and liquid polyol, wherein the combined weight of liquid sugars and liquid polyols amounts to from 40 to 95% solids by weight of the aqueous liquid component, and the continuous aqueous liquid component preferably contains less than 20% water. An optional suspended solids portion can be employed. The creamy product, wherein the moisture content is from 2 to 10% by weight of the total composition, and the combined amount of the sugar, polyol and other soluble solids comprises from about 25 to 65% of the total product and is sufficient to provide an Aw of less than 0.5 for the total product, can be combined with a bakeable dough and baked.Type: GrantFiled: July 10, 2003Date of Patent: March 8, 2005Assignee: Kraft Foods Holdings, Inc.Inventors: Jeanny Zimeri, Chii-Fen Wang, Zhen-Yi Yan, Harry Levine, Louise Slade, Weizhu Yu, Julia Leigh DesRochers
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Publication number: 20040126464Abstract: A creamy product with a lubricious mouthfeel is bake-stable and suitable as a filler or topping for baked goods. In a preferred form, it comprises: at least 30% by weight of a discontinuous fat portion; at least 20% of a continuous aqueous liquid component for providing sweetness and stability, comprising liquid sugar and liquid polyol, wherein the combined weight of liquid sugars and liquid polyols amounts to from 40 to 95% solids by weight of the aqueous liquid component, and the continuous aqueous liquid component preferably contains less than 20% water. An optional suspended solids portion can be employed. The creamy product, wherein the moisture content is from 2 to 10% by weight of the total composition, and the combined amount of the sugar, polyol and other soluble solids comprises from about 25 to 65% of the total product and is sufficient to provide an Aw of less than 0.5 for the total product, can be combined with a bakeable dough and baked.Type: ApplicationFiled: July 10, 2003Publication date: July 1, 2004Inventors: Jeanny Zimeri, Chii-Fen Wang, Zhen-Yi Yan, Harry Levine, Louise Slade, Weizhu Yu, Julia Leigh DesRochers
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Publication number: 20020155198Abstract: A savory, smooth-textured, bakeable and shelf-stable product is prepared as a three-phase formulation, including an aqueous liquid phase, a dispersed fat phase and a solids phase, preferably containing cheese in significant proportion. The liquid phase is present in sufficient quantity to suspend and disperse the fat and solids phases. The dispersed fat must have sufficiently small droplet size raise the viscosity for this phase sufficiently to result in a creamy texture for the final product. The savory flavor ingredients are present as undissolved solids of sufficiently small particle size to provide the proper flavor release for the flavor and a texture consistent with the savory flavor. Preferred cheese products will have a lubricous, slippery, smooth mouthfeel and a flavor release that endures until the palate is essentially clean. The product can be applied to unbaked doughs prior to baking and retain their desired properties after baking.Type: ApplicationFiled: January 30, 2002Publication date: October 24, 2002Inventors: Chii-Fen Wang, Weizhu Yu, Harry Levine, Ramanathan Santhanagopalan, Louise Slade, Zhen-Yi Yan
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Patent number: 6461657Abstract: A process is provided for making a prepared mustard product having reduced tendency for syneresis. A slurry is prepared to contain ground mustard seed, water, vinegar, salt and an amount of type JMJ pectin effective to reduce the tendency toward syneresis, e.g., from about 0.1 to 0.5% by weight. The resulting slurry is then homogenized sufficiently to provide a viscosity of from 7,000 to 25,000 centipoises after setting. Upon packaging, the product will have less tendency to suffer separation of water to form a free phase.Type: GrantFiled: July 19, 2000Date of Patent: October 8, 2002Inventors: Douglas H. Philipsen, Weizhu Yu, Koo H. Chung, William Richard Drummond