Abstract: The present invention relates to a series of new fusidic acid derivatives and salts or easily hydrolysable esters thereof, to the preparation of these compounds and to pharmaceutical compositions containing the compounds. The new compounds have the general formula: ##STR1## in which R.sub.1 and R.sub.2 stand for an alkanoyl, aralkanoyl or aroyl radical and R.sub.2 also can be hydrogen; the dotted line between C-24 and C-25 indicates a double bond or a single bond, and the wavy line at C-3 indicates that OR.sub.1 is either .alpha.-oriented or .beta.-oriented. The compounds of the invention have a remarkable anti-inflammatory effect and cause a pronounced relief on patients suffering from arthritis.The invention also concerns intermediates which in themselves to some extent have an anti-inflammatory activity.

Abstract: The invention relates to a series of new compounds, to salts of these compounds and to methods for the preparation of the compounds. The new compounds have the general formula: ##EQU1## in which n is an integer from 0 to 5; and A is selected from the group consisting of an unsubstituted or substituted aliphatic, alicyclic, aromatic and heterocyclic radical.The compounds of the invention are broad-spectrum antibiotics especially usable for oral administration.

Abstract: New penicillin esters and their salts together with methods for, and intermediates in the preparation thereof, the esters having the formula: ##EQU1## in which formula the asterisk indicates the possibility of an asymmetric carbon atom, n indicates an integer from 0 to 5, R.sup.1 represents a group, which together with --CO-- forms the side chain of any of the known semisynthetic, biosynthetic, and natural penicillins; R.sup.2 has any of the following meanings: hydrogen, an aliphatic, an aromatic, a heterocyclic group, and an aromatically substituted aliphatic group; each of R.sup.3, R.sup.4, and R.sup.5 represents hydrogen, or a lower aliphatic group with the provision that R.sup.2 and R.sup.5 together with the carbon atom between them can form a 5-, 6-, or 7-membered carbocyclic ring, and either R.sup.3 and R.sup.4, or R.sup.4 and R.sup.5 together with the nitrogen atom can form a ring system.