Patents by Inventor Welfhard Engel

Welfhard Engel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-ones substituted in the 11-position for treating bradycardia and bradyarrhythmia in human and veterinary medicine
    Patent number: 5026699
    Abstract: 5,11-Dihydro-6H-pyrido[2,3-b][1,4]-benzo-diazepinones substituted in the 11-position corresponding to general formula I ##STR1## wherein R.sup.1 and R.sup.2 represent hydrogen atoms or alkyl groups having 1 to 3 carbon atoms, A.sup.1 is a straight-chained or branched alkylene group with 1 to 5 carbon atoms, A.sup.2 is a methylene group or, if R.sup.1 is hydrogen and R.sup.2 is methyl, A.sup.2 may also be an ethylene group, and the physiologically acceptable acid addition salts thereof are suitable for treating bradycardia and bradyarrhythmia and spasm in the colon, bladder and bronchi.
    Type: Grant
    Filed: June 15, 1989
    Date of Patent: June 25, 1991
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Gerhard Mihm, Wolfgang Eberlein, Welfhard Engel, Gunter Trummlitz, Norbert Mayer, Henri Doods, Rudolf Hammer