Patents by Inventor Wen-Bin Lee
Wen-Bin Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220314222Abstract: An array microfluidic chip includes a chip mainbody, a transparent hydrophilic membrane, and a covering sheet. The chip mainbody includes a sample loading well and a plurality of reaction wells. The reaction wells are respectively connected to the sample loading well and arranged in an array form. The transparent hydrophilic membrane is disposed on the chip mainbody and covers the reaction wells. The transparent hydrophilic membrane includes a plurality of air pores and a first opening. The air pores are respectively connected to one of the reaction wells. The covering sheet covers the air pores and includes an adhesive element and a vent hole. The covering sheet, the adhesive element and the transparent hydrophilic membrane are stacked to form a vent space.Type: ApplicationFiled: September 30, 2021Publication date: October 6, 2022Inventors: Wen-Bin Lee, Shu-Hsien Liao
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Patent number: 11007524Abstract: The present disclosure provides an automatic microfluidic system for rapid personalized drug screening including a microfluidic chip. The microfluidic chip includes a fluid storage unit, a fluid driving unit, a reaction unit and a plurality of valve units. The fluid driving unit includes two mixing pumps. Each of the mixing pumps includes two pneumatic micro-pumps, a mixing chamber and a blocking structure. The blocking structure is disposed in the mixing chamber and is connected between the two pneumatic micro-pumps. When the two pneumatic micro-pumps are started alternately, the blocking structure is deflected alone with the operation of the two pneumatic micro-pumps.Type: GrantFiled: January 18, 2019Date of Patent: May 18, 2021Assignees: National Tsing Hua University, Kaohsiung Chang Gung Medical UniversityInventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Huey-Ling You
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Publication number: 20200230597Abstract: The present disclosure provides an automatic microfluidic system for rapid personalized drug screening including a microfluidic chip. The microfluidic chip includes a fluid storage unit, a fluid driving unit, a reaction unit and a plurality of valve units. The fluid driving unit includes two mixing pumps. Each of the mixing pumps includes two pneumatic micro-pumps, a mixing chamber and a blocking structure. The blocking structure is disposed in the mixing chamber and is connected between the two pneumatic micro-pumps. When the two pneumatic micro-pumps are started alternately, the blocking structure is deflected alone with the operation of the two pneumatic micro-pumps.Type: ApplicationFiled: January 18, 2019Publication date: July 23, 2020Inventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Huey-Ling You
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Patent number: 10610863Abstract: An automatic microfluidic system for antibiotic susceptibility testing of the present disclosure at least includes a microfluidic chip. The microfluidic chip includes a fluid storage unit, a reaction unit, a pneumatic micro-pumping unit and a plurality of valve units. The fluid storage unit is provided for storing a bacterial suspension, a broth and an antibiotic solution. The reaction unit includes a first reaction chamber and at least two second reaction chambers. The pneumatic micro-pumping unit is adjacently disposed to the fluid storage unit and the reaction unit for selectively, repeatedly and quantitatively transporting the broth, the bacterial suspension and the antibiotic solution to the reaction unit to form a first mixing solution and at least two second mixing solutions. The valve units include a plurality of pneumatic micro-valves and a plurality of valve control air holes for controlling the opening and closing of the pneumatic micro-valves.Type: GrantFiled: May 1, 2017Date of Patent: April 7, 2020Assignees: NATIONAL TSING HUA UNIVERSITY, Kaohsiung Chang Gung Memorial HospitalInventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Wen-Hsin Chang
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Patent number: 10274497Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnnnnnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.Type: GrantFiled: February 6, 2017Date of Patent: April 30, 2019Assignee: National Tsing Hua UniversityInventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
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Patent number: 10107817Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.Type: GrantFiled: January 20, 2017Date of Patent: October 23, 2018Assignee: NATIONAL TSING HUA UNIVERSITYInventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
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Publication number: 20180142279Abstract: An automatic microfluidic system for antibiotic susceptibility testing of the present disclosure at least includes a microfluidic chip. The microfluidic chip includes a fluid storage unit, a reaction unit, a pneumatic micro-pumping unit and a plurality of valve units. The fluid storage unit is provided for storing a bacterial suspension, a broth and an antibiotic solution. The reaction unit includes a first reaction chamber and at least two second reaction chambers. The pneumatic micro-pumping unit is adjacently disposed to the fluid storage unit and the reaction unit for selectively, repeatedly and quantitatively transporting the broth, the bacterial suspension and the antibiotic solution to the reaction unit to form a first mixing solution and at least two second mixing solutions. The valve units include a plurality of pneumatic micro-valves and a plurality of valve control air holes for controlling the opening and closing of the pneumatic micro-valves.Type: ApplicationFiled: May 1, 2017Publication date: May 24, 2018Inventors: Gwo-Bin LEE, Shiuann-Sheng LEE, Wen-Bin LEE, Wen-Hsin CHANG
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Publication number: 20180133713Abstract: A microfluidic in-vitro screening chip system including a first micromixer chamber, a plurality of first storage chambers, a second micromixer chamber and a plurality of second storage chambers. The first micromixer chamber includes a non-target disease tissue slide region. The plurality of first storage chambers are connected to the first micromixer chamber, wherein at least one first storage chamber is used for storing a library. The second micromixer chamber is connected to the first micromixer chamber, and the second micromixer chamber includes a target disease tissue slide region. The plurality of second storage chambers are connected to the second micromixer chamber.Type: ApplicationFiled: February 14, 2017Publication date: May 17, 2018Applicant: National Tsing Hua UniversityInventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
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Publication number: 20180136217Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnimnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.Type: ApplicationFiled: February 6, 2017Publication date: May 17, 2018Applicant: National Tsing Hua UniversityInventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
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Publication number: 20180113136Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.Type: ApplicationFiled: January 20, 2017Publication date: April 26, 2018Inventors: Gwo-Bin LEE, Lien-Yu HUNG, Chih-Hung WANG, Chien-Yu FU, Wen-Bin LEE
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Patent number: 7128671Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.Type: GrantFiled: July 6, 2004Date of Patent: October 31, 2006Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Publication number: 20040238245Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.Type: ApplicationFiled: July 6, 2004Publication date: December 2, 2004Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Patent number: 6663524Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a speed converter, a clutch, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.Type: GrantFiled: December 31, 2001Date of Patent: December 16, 2003Assignee: Industrial Technology Research InstituteInventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Patent number: 6659910Abstract: A hybrid power system with continuously variable speed, comprising a first power unit, a secondary shaft, a speed converter, a clutch, a second transmission device, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft and has a drum, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The second transmission device is connected with the drum of the clutch. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.Type: GrantFiled: December 20, 2001Date of Patent: December 9, 2003Assignee: Industrial Technology Research InstituteInventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Publication number: 20030098188Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.Type: ApplicationFiled: December 20, 2001Publication date: May 29, 2003Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Publication number: 20030092529Abstract: A hybrid power system with continuously variable speed, comprising a first power unit, a secondary shaft, a speed converter, a clutch, a second transmission device, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft and has a drum, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The second transmission device is connected with the drum of the clutch. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.Type: ApplicationFiled: December 20, 2001Publication date: May 15, 2003Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Publication number: 20030092525Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a speed converter, a clutch, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.Type: ApplicationFiled: December 31, 2001Publication date: May 15, 2003Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
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Patent number: 4872401Abstract: An apparatus for improving the flavor of and removing the flavor of a fermented substance such as wine, sauce, tobacco or the like which includes a container including a surrounding side wall, and a plurality of elongated magnetic members mounted on an inner side of the surrounding side wall. Like poles of the magnetic pieces are placed adjacently so as to induce a high density magnetic field inside the container.Type: GrantFiled: July 5, 1988Date of Patent: October 10, 1989Inventor: Wen-bin Lee