Patents by Inventor Wen-Bin Lee

Wen-Bin Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220314222
    Abstract: An array microfluidic chip includes a chip mainbody, a transparent hydrophilic membrane, and a covering sheet. The chip mainbody includes a sample loading well and a plurality of reaction wells. The reaction wells are respectively connected to the sample loading well and arranged in an array form. The transparent hydrophilic membrane is disposed on the chip mainbody and covers the reaction wells. The transparent hydrophilic membrane includes a plurality of air pores and a first opening. The air pores are respectively connected to one of the reaction wells. The covering sheet covers the air pores and includes an adhesive element and a vent hole. The covering sheet, the adhesive element and the transparent hydrophilic membrane are stacked to form a vent space.
    Type: Application
    Filed: September 30, 2021
    Publication date: October 6, 2022
    Inventors: Wen-Bin Lee, Shu-Hsien Liao
  • Patent number: 11007524
    Abstract: The present disclosure provides an automatic microfluidic system for rapid personalized drug screening including a microfluidic chip. The microfluidic chip includes a fluid storage unit, a fluid driving unit, a reaction unit and a plurality of valve units. The fluid driving unit includes two mixing pumps. Each of the mixing pumps includes two pneumatic micro-pumps, a mixing chamber and a blocking structure. The blocking structure is disposed in the mixing chamber and is connected between the two pneumatic micro-pumps. When the two pneumatic micro-pumps are started alternately, the blocking structure is deflected alone with the operation of the two pneumatic micro-pumps.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: May 18, 2021
    Assignees: National Tsing Hua University, Kaohsiung Chang Gung Medical University
    Inventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Huey-Ling You
  • Publication number: 20200230597
    Abstract: The present disclosure provides an automatic microfluidic system for rapid personalized drug screening including a microfluidic chip. The microfluidic chip includes a fluid storage unit, a fluid driving unit, a reaction unit and a plurality of valve units. The fluid driving unit includes two mixing pumps. Each of the mixing pumps includes two pneumatic micro-pumps, a mixing chamber and a blocking structure. The blocking structure is disposed in the mixing chamber and is connected between the two pneumatic micro-pumps. When the two pneumatic micro-pumps are started alternately, the blocking structure is deflected alone with the operation of the two pneumatic micro-pumps.
    Type: Application
    Filed: January 18, 2019
    Publication date: July 23, 2020
    Inventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Huey-Ling You
  • Patent number: 10610863
    Abstract: An automatic microfluidic system for antibiotic susceptibility testing of the present disclosure at least includes a microfluidic chip. The microfluidic chip includes a fluid storage unit, a reaction unit, a pneumatic micro-pumping unit and a plurality of valve units. The fluid storage unit is provided for storing a bacterial suspension, a broth and an antibiotic solution. The reaction unit includes a first reaction chamber and at least two second reaction chambers. The pneumatic micro-pumping unit is adjacently disposed to the fluid storage unit and the reaction unit for selectively, repeatedly and quantitatively transporting the broth, the bacterial suspension and the antibiotic solution to the reaction unit to form a first mixing solution and at least two second mixing solutions. The valve units include a plurality of pneumatic micro-valves and a plurality of valve control air holes for controlling the opening and closing of the pneumatic micro-valves.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: April 7, 2020
    Assignees: NATIONAL TSING HUA UNIVERSITY, Kaohsiung Chang Gung Memorial Hospital
    Inventors: Gwo-Bin Lee, Shiuann-Sheng Lee, Wen-Bin Lee, Wen-Hsin Chang
  • Patent number: 10274497
    Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnnnnnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: April 30, 2019
    Assignee: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Patent number: 10107817
    Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: October 23, 2018
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180142279
    Abstract: An automatic microfluidic system for antibiotic susceptibility testing of the present disclosure at least includes a microfluidic chip. The microfluidic chip includes a fluid storage unit, a reaction unit, a pneumatic micro-pumping unit and a plurality of valve units. The fluid storage unit is provided for storing a bacterial suspension, a broth and an antibiotic solution. The reaction unit includes a first reaction chamber and at least two second reaction chambers. The pneumatic micro-pumping unit is adjacently disposed to the fluid storage unit and the reaction unit for selectively, repeatedly and quantitatively transporting the broth, the bacterial suspension and the antibiotic solution to the reaction unit to form a first mixing solution and at least two second mixing solutions. The valve units include a plurality of pneumatic micro-valves and a plurality of valve control air holes for controlling the opening and closing of the pneumatic micro-valves.
    Type: Application
    Filed: May 1, 2017
    Publication date: May 24, 2018
    Inventors: Gwo-Bin LEE, Shiuann-Sheng LEE, Wen-Bin LEE, Wen-Hsin CHANG
  • Publication number: 20180133713
    Abstract: A microfluidic in-vitro screening chip system including a first micromixer chamber, a plurality of first storage chambers, a second micromixer chamber and a plurality of second storage chambers. The first micromixer chamber includes a non-target disease tissue slide region. The plurality of first storage chambers are connected to the first micromixer chamber, wherein at least one first storage chamber is used for storing a library. The second micromixer chamber is connected to the first micromixer chamber, and the second micromixer chamber includes a target disease tissue slide region. The plurality of second storage chambers are connected to the second micromixer chamber.
    Type: Application
    Filed: February 14, 2017
    Publication date: May 17, 2018
    Applicant: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180136217
    Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnimnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 17, 2018
    Applicant: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180113136
    Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.
    Type: Application
    Filed: January 20, 2017
    Publication date: April 26, 2018
    Inventors: Gwo-Bin LEE, Lien-Yu HUNG, Chih-Hung WANG, Chien-Yu FU, Wen-Bin LEE
  • Patent number: 7128671
    Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: October 31, 2006
    Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Publication number: 20040238245
    Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.
    Type: Application
    Filed: July 6, 2004
    Publication date: December 2, 2004
    Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Patent number: 6663524
    Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a speed converter, a clutch, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.
    Type: Grant
    Filed: December 31, 2001
    Date of Patent: December 16, 2003
    Assignee: Industrial Technology Research Institute
    Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Patent number: 6659910
    Abstract: A hybrid power system with continuously variable speed, comprising a first power unit, a secondary shaft, a speed converter, a clutch, a second transmission device, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft and has a drum, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The second transmission device is connected with the drum of the clutch. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: December 9, 2003
    Assignee: Industrial Technology Research Institute
    Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Publication number: 20030098188
    Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a first transmission device, an auxiliary power unit, and a second transmission device. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The first transmission device is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The auxiliary power unit has an electric motor with a driving shaft, which is parallel to the primary shaft. The second transmission device is placed between the primary shaft and the driving shaft, transmitting torque from the electric motor to the primary shaft.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 29, 2003
    Inventors: Huan-Lung Gu, Chin-Tai Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Publication number: 20030092529
    Abstract: A hybrid power system with continuously variable speed, comprising a first power unit, a secondary shaft, a speed converter, a clutch, a second transmission device, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft and has a drum, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The second transmission device is connected with the drum of the clutch. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 15, 2003
    Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Publication number: 20030092525
    Abstract: A hybrid power system, comprising a first power unit, a secondary shaft, a speed converter, a clutch, and an electric motor. The first power unit has a primary shaft. The secondary shaft is driven by the primary shaft in a rotational movement. The speed converter is placed between the primary shaft and the secondary shaft, having a transmission belt, transmitting torque from the primary shaft to the secondary shaft. The clutch is set on the primary shaft or on the secondary shaft, allowing or interrupting transmission of torque from the first power unit to the secondary shaft. The electric motor is connected with the secondary shaft, either driving the secondary shaft or being driven by the secondary shaft to generate electricity or running idle.
    Type: Application
    Filed: December 31, 2001
    Publication date: May 15, 2003
    Inventors: Huan-Lung Gu, Chin-Taz Wu, Pan-Hsiang Hsieh, Wen-Bin Lee, Chun-Hsien Lu
  • Patent number: 4872401
    Abstract: An apparatus for improving the flavor of and removing the flavor of a fermented substance such as wine, sauce, tobacco or the like which includes a container including a surrounding side wall, and a plurality of elongated magnetic members mounted on an inner side of the surrounding side wall. Like poles of the magnetic pieces are placed adjacently so as to induce a high density magnetic field inside the container.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: October 10, 1989
    Inventor: Wen-bin Lee